1.
J Chromatogr
; 273(2): 393-7, 1983 Apr 08.
Article
in English
| MEDLINE
| ID: mdl-6863451
2.
Clin Chim Acta
; 121(1): 79-86, 1982 May 06.
Article
in English
| MEDLINE
| ID: mdl-7083596
ABSTRACT
In order to develop a gas chromatographic method with flame ionization detection for the analysis of urinary 3-methoxy-4-hydroxyphenylethyleneglycol sulphate, a new procedure for its isolation has been introduced. The conjugated metabolite has been extracted by an ion-pair technique using tetrabutyl ammonium as counter ion and dichloromethane as organic solvent. Hydrolysis and derivatization of 3-methoxy-4-hydroxyphenylethyleneglycol sulphate have been finally performed by treatment with heptafluorobutyric anhydride. Each step of the procedure, applied to the analysis of urine samples both from normal subjects and from patients with neuroblastoma, has been discussed.