Histomorphometric study of dental pulp during orthodontic tooth movement.

Orthodontic tooth movement has been implicated in secondary changes to the dental pulp. The purpose of this study was to correlate the effects of orthodontic tooth movement on the dental pulp by histomorphometric parameters. Four groups, each consisting of 36 male adult Sprague-Dawley strain rats, were studied with differing force magnitudes. These included a sham group in addition to groups with bilaterally placed appliances activated to 20, 40, and 60 g of initial force designed to mesially tip the maxillary first molars. Six rats were killed at 1, 3, 5, 7, 10, and 14 days. Specimens were fixed, embedded, and stained with tetrachrome. Pulpal measurements were made with an image analyzer and included changes in predentin and vascularity. Findings indicated a significant increase (p < or = 0.05) relative to time and force magnitude in capillary number. An initial pulpal hyperemia was observed following activation of orthodontic force which was unrelated to force magnitude. A force-dependent increase in predentin width was measured at the peak of the tooth movement cycle.

Evaluation of three silicone-based materials as potential retrograde fillings in surgical endodontics.

Endodontic therapy has played an important role in maintaining the integrity of the natural dentition as a fully functional and esthetic masticatory apparatus. Although the sealing of the root canal system is usually accomplished by the conservative endodontic approach, cases which have failed or which involve perforations, broken instruments, or post-crown restorations are almost always treated surgically by using zinc-free amalgam as a retrograde filling material. However, the literature is controversial concerning the health risks and benefits of this material. For this reason, the study presented here was initiated to evaluate the potential of (a) a medical grade silicone-titanium mesh compound; (b) Endo-Fill (Lee Pharmaceuticals, El Monte, CA); and (c) an experimental expanding Endo-Fill (Lee Pharmaceuticals) as alternatives to amalgam. The three silicone-based materials and amalgam were compared for linear apical dye leakage. The leakage study involved 80 teeth which were instrumented, obturated, and prepared surgically for one of the four test materials. Either the teeth were placed immediately into 1% methylene blue dye or the material was allowed to set for 24 h before placement into the dye. Endo-Fill showed significantly less leakage than did the other materials in both the immediately placed and the 24-h set groups. On the other extreme, the experimental expanding Endo-Fill allowed significantly more dye penetration than did amalgam and the other silicone variations.