ABSTRACT
The impairment of the nervous system is the main clinical presentation of chronic Lyme borreliosis. Frequency and characteristics of neuroborreliosis in Russia are still under-investigated. The article contains the analysis of 160 cases of chronic Lyme borreliosis with detailed descriptions of different neurologic syndromes - radiculopathy, polyneuropathy, encephalopathy and encephalomyelitis. Epidemiology of this disease as well as its laboratory and instrumental diagnosis are discussed. Extraneural signs and symptoms of late stages of neuroborreliosis are presented. The results of antibacterial treatment of different forms of chronic neuroborreliosis are outlined.
Subject(s)
Lyme Neuroborreliosis/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Chronic Disease , Encephalomyelitis/diagnosis , Encephalomyelitis/drug therapy , Encephalomyelitis/physiopathology , Female , Humans , Lyme Neuroborreliosis/drug therapy , Lyme Neuroborreliosis/physiopathology , Male , Middle Aged , Polyneuropathies/diagnosis , Polyneuropathies/drug therapy , Polyneuropathies/physiopathology , Radiculopathy/diagnosis , Radiculopathy/drug therapy , Radiculopathy/physiopathology , Syndrome , Young AdultABSTRACT
A total of 111 patients with myocardial infarction were studied in the early, period of the disease. Exercise and information load tests, impedance plethysmography, electrocardiography, and large-framed fluorography were performed. Among the patients with myocardial infarction who responded to information load by exhibiting transient silent ischemia, vasospastic reactions were demonstrated to be diagnosed mainly in those with posterior myocardial infarction. The patients with anterior myocardial infarction responded to psychoemotional stress mainly by showing ischemia formed under the conditions of higher myocardial oxygen uptake due to increased blood minute volume. In most patients, the area of silent psychogenic vasospastic ischemia coincided with that of infarct-related myocardium, whereas ischemic changes were largely located in the anterior left ventricular wall despite the area of myocardial necrosis when psychogenic ischemia developed with increased myocardial oxygen uptake.
Subject(s)
Myocardial Infarction/physiopathology , Myocardial Ischemia/psychology , Adult , Humans , Middle Aged , Myocardial Infarction/pathology , Myocardial Ischemia/physiopathology , Oxygen Consumption/physiology , Stress, Psychological/physiopathologyABSTRACT
When restorative treatment was performed in 51 patients with myocardial infarction, 3 groups were identified, each including 17 persons. The main group comprised those whose rehabilitation had been achieved by early physical trainings with coronary active agents; the first control consisted of those who had gone in for physical exercises and received antianginal drugs, the second control group included those whose rehabilitation had been conducted by the well-known procedures (therapeutical exercises, graded walking, nitrates, beta-blockers, calcium antagonists). The treatment resulted in improvement in the functional status of patients from the main and the first control groups as compared to those from the second control group. It is concluded that in patients with myocardial infarction without pain syndrome in the subacute period of the disease the efficiency of restorative treatment may be enhanced by using early individualized physical trainings without application of coronary active drugs.
