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Molecular detection and characterization of noroviruses from children in Botswana.
Mattison, Kirsten; Sebunya, Teresa K; Shukla, Anu; Noliwe, Lebani N; Bidawid, Sabah.
J Med Virol ; 82(2): 321-4, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20029818

ABSTRACT

Stool specimens were collected from 100 children in Botswana. RT-PCR analysis detected noroviruses (NoVs) in 24% of samples tested. Genogroup I and genogroup II strains were identified. There was no association between NoV detection and age or gender. This study is the first indication that NoVs circulate widely in Botswana.


Subject(s)
Caliciviridae Infections/virology , Norovirus/genetics , Norovirus/isolation & purification , Botswana , Child , Child, Preschool , Cluster Analysis , Feces/virology , Female , Genotype , Humans , Infant , Infant, Newborn , Male , Molecular Sequence Data , Norovirus/classification , RNA, Viral/genetics , Reverse Transcriptase Polymerase Chain Reaction , Sequence Analysis, DNA , Sequence Homology
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