ABSTRACT
Condensing osteitis of the clavicle is a rare, benign, usually painful condition leading to sclerosis of the medial end of the clavicle. In the English language literature, this has only been reported in women since its original description by Brower et al. in 1974 [1]. We report a clavicular lesion occurring in a man that is clinically, radiographically, and histologically identical to described cases of condensing osteitis.
Subject(s)
Clavicle/diagnostic imaging , Osteitis/diagnostic imaging , Adult , Biopsy , Bone Remodeling , Clavicle/pathology , Humans , Male , Osteitis/pathology , Osteosclerosis/pathology , Osteotomy , Tomography, X-Ray ComputedABSTRACT
The inferolateral trunk arises from the internal carotid artery at C-4 and provides vascular supply to cranial nerves III to VI. We report a patient who developed neuropathies of cranial nerves III, V1-3, and VI, 48 hours after infusion of cisplatin into the right internal carotid artery for an anaplastic oligoastrocytoma. The clinical and radiographic findings implicated direct toxicity to nerves in the distribution of the inferolateral trunk. We found additional cases by review of published brain tumor chemotherapy trials, thus identifying a novel, toxic neurovascular mechanism for injury to cranial nerves III to VI.
