Quality assurance of electron beams using a Varian electronic portal imaging device.

The feasibility of utilizing an electronic portal imaging device (EPID) for the quality assurance of electron beams was investigated. This work was conducted on a Varian 2100iX machine equipped with an amorphous silicon (aS1000) portal imager. The linearity of the imager pixel response as a function of exposed dose was first confirmed. The short-term reproducibility of the EPID response to electron beams was verified. Low (6 MeV), medium (12 MeV) and high (20 MeV) energies were tested, each along with small (6 × 6 cm(2)), medium (10 × 10 cm(2)) and large (20 × 20 cm(2)) applicators. Acquired EPID images were analyzed using an in-house MATLAB code for radiation field size, penumbra, symmetry and flatness. Field sizes and penumbra values agreed with those from film dosimetry to within 1 mm. Field symmetry and flatness constancies were measured over a period of three weeks. The results indicate that EPID can be used for routine quality assurance of electron beams.

SU-E-T-94: Multileaf Collimator Performance and Validation of Quality Control Tolerances.

PURPOSE: The automated quality assurance system (AQUA) is a centralized quality control (QC) software designed to automate QC tests. Statistical analysis of AQUA results was performed to assess the geometric accuracy and long-term reproducibility of a commercially available multileaf collimator (MLC) and examine the applicability of the American Association of Physicists in Medicine (AAPM) tolerances for MLC QC. METHODS: The MLC was first calibrated with AQUA by minimizing leaf-positioning errors on megavoltage images for 5 different leaf-bank positions (-60 to 100 mm from radiation isocenter). Leaf-positioning accuracy and reproducibility was assessed by repeating the AQUA test 5 times/week. The range of leaf-positioning error over leaf-bank positions and time was reported. Measured leaf-positioning errors were then separated into systematic and random error components. The systematic error corresponds to the variation (standard deviation) in mean positioning errors between leaves over leaf-bank positions and time. The random error quantifies the leaf position variations around its mean and is calculated as the root-mean-square of the individual leaf position standard deviations. RESULTS: To date, 2 different MLCs have been calibrated using AQUA and 9-18 datasets have been acquired to assess performance. For the unit with the longest follow up, the range of leaf-positioning errors was -0.62 to 0.85 mm and 98% of the measured leaf positions (n=7200) were within ±0.5 mm of the nominal position. The systematic error was the main error component (±0.15 to ±0.2 mm) and was attributed to the residual errors after calibration. The random error was ±0.07 mm for both units and demonstrated good leaf-positioning reproducibility and limited uncertainty of the AQUA measurements. CONCLUSIONS: Preliminary results show that after MLC calibration with AQUA, leaf-positioning errors on two different units are well within the AAPM-recommended ±1 mm tolerances. Additional MLC performance improvement is possible if residual errors after calibration can be reduced further as the MLC demonstrated high reproducibility. Funded in part by Elekta Inc.

Poster - Thurs Eve-31: Clinical implementation and experience with EPID-based precision isocentre localization.

Modern linear accelerators contain multiple isocentres, defined by the mechanical motions of gantry, collimator and table. Isocentre localization for these motions has been performed using film and manual evaluations which have difficulty in relating the individual motions. To address these limitations, we have developed an EPID based technique to measure the isocentre position for each of the treatment unit motions. This technique uses the projected position of a radio-opaque marker at the isocentre in a series of MV images to determine the motion of the isocentre. This analytical procedure has been implemented in the clinic using a MatLab code to automatically analyze images and determine both the isocentre position and motion about the mean for each of gantry, collimator and table. Results of isocentre measurements for 18 machines from 2 different vendors at 2 separate clinics are reported. These measurements show that while the position of the mean isocentres are contained within a 2mm sphere, combinations of gantry, table and collimator rotations can be found that result in treatment isocentres more than 2mm apart. Results for a treatment unit, which underwent a recent equipment upgrade, are also presented that show a small change in the location of the gantry relative to the table isocentre. The implementation of this of isocentre localization technique has provided important clinical information which can be efficiently completed in less than an hour. This information is an important consideration in monitoring the changes and in assessing the treatment precision that can be obtained.

A novel four-dimensional radiotherapy method for lung cancer: imaging, treatment planning and delivery.

We present treatment planning methods based on four-dimensional computed tomography (4D-CT) to incorporate tumour motion using (1) a static field and (2) a dynamic field. Static 4D fields are determined to include the target in all breathing phases, whereas dynamic 4D fields are determined to follow the shape of the tumour assessed from 4D-CT images with a dynamic weighting factor. The weighting factor selection depends on the reliability of patient breathing and limitations of the delivery system. The static 4D method is compared with our standard protocol for gross tumour volume (GTV) coverage, mean lung dose and V20. It was found that the GTV delineated on helical CT without incorporating breathing motion does not adequately represent the target compared to the GTV delineated from 4D-CT. Dosimetric analysis indicates that the static 4D-CT based technique results in a reduction of the mean lung dose compared with the standard protocol. Measurements on a moving phantom and simulations indicated that 4D radiotherapy (4D-RT) synchronized with respiration-induced motion further reduces mean lung dose and V20, and may allow safe application of dose escalation and CRT/IMRT. The motions of the chest cavity, tumour and thoracic structures of 24 lung cancer patients are also analysed.

A dose-per-pulse monitor for a dual-mode medical accelerator.

On a radiotherapy accelerator, the dose monitoring system is the last level of protection between the patient and the extremely high dose rate which all accelerators are capable of producing. The risk of losing this level of protection is substantially reduced if two or more dose monitoring systems are used which are mechanically and electrically independent in design. This paper describes the installation of an independent radiation monitor in a dual-mode, computer-controlled accelerator with a moveable monitor chamber. The added device is fixed in the beam path, is capable of monitoring each beam pulse, and is capable of terminating irradiation within the pulse repetition period if any measured pulse is unacceptably high.