Contribution of obesity in increasing type 2 diabetes prevalence in Iranian urban and rural adults during recent decade.

BACKGROUND AND OBJECTIVES: The prevalence of both obesity and type 2 diabetes has increased in recent years. In this study, we aimed to evaluate the prevalence of obesity and type 2 diabetes and to investigate the contribution of obesity to the increased prevalence of type 2 diabetes in urban and rural Iranian communities. METHODS: This study was based on four surveys from the Surveillance Survey of Risk Factors of Non-communicable Diseases (SuRFNCD), conducted in 2005, 2007, 2011, and 2016. The contribution of general and abdominal obesity to the prevalence of type 2 diabetes was determined based on the population attributable fraction (PAF). RESULTS: The mean (95% CI) age and body mass index (BMI) of the participants were 36.9 years (36.8-36.9) and 25.9 kg/m2 (25.9-26.0), respectively. The increasing rates of general obesity and diabetes were 37% and 80% among urban residents and 63% and 68% among rural residents, respectively. The PAF of general obesity and abdominal obesity to the prevalence of type 2 diabetes was 20.2% and 33.4% in urban residents and 11.8% and 21.0% in rural residents, respectively. CONCLUSION: The prevalence of both obesity and type 2 diabetes has increased over the past 12 years. Besides, general and abdominal obesity played a substantial role in increasing the prevalence of type 2 diabetes in both urban and rural populations.

Oral Health-Related Quality of Life in Patients with Rheumatoid Arthritis.

INTRODUCTION: The assessment of the quality of life (QOL) in rheumatoid arthritis (RA) patients is of great importance for health researchers, health planners, and clinical specialists. Thus, the present study aimed to evaluate the oral health-related quality of life in patients with RA. MATERIALS AND METHODS: In this case-control study, data were collected by two standard questionnaires filled by 80 patients with rheumatoid arthritis and 80 healthy individuals. They were analyzed using independent t-test, chi-square test, Mann-Whitney test, Pearson's correlation coefficient, and Kruskal-Wallis test in SPSS 21. RESULTS: The mean of Health Assessment Questionnaire (HAQ) score in RA patients and control groups was 1.17± 0.89 and 0.35±0.12, respectively, and the mean of General Oral Health Assessment Index (GOHAI) score in patients and control groups was 37.46±9.53 and 53.21±11.35, respectively; 62.5% of the patients got HAQ score more than or equal to 1 (≥1) and 91.2% got GOHAI score less than or equal to 50 (≤50). CONCLUSION: The results of the present study suggested that most of the patients with RA had a poor oral health quality of life. Deterioration of disease and aging decrease the GOHAI and the oral health quality of life of patients.

The comparison of the effect of curcumin with nystatin on inhibition level of Candida albicans.

BACKGROUND: Curcumin is a kind of medicinal plant, a member of the ginger family, Zingiberaceae. As the herbal medicine has been globally demanded in recent years and due to the anti-viral, anti-inflammatory, and antifungal properties of curcumin, the present study aimed to compare the inhibitory effect of curcumin with that of nystatin on Candida albicans growth. METHODS: In this experimental study, the antifungal effect of curcumin on Candida albicans was evaluated. Candida albicans is cultivated in Agar Sabuard medium containing chlorophenic, 10-series of curcumin extract, and one 10-series of a disc impregnated with nystatin. Inside of each plate, one disc of herbal extract, one disc of nystatin as a positive control, one disc of methanol and one empty disc as negative control were placed, after 24 hrs, the inhibitory zone diameter of the herbal extract was compared with that of positive control using Mann-Whitney. RESULTS: The mean of inhibitory zone diameter in nystatin and curcumin was 1.04±20.46 and 1.36±0.89 mm, respectively. Mann-Whitney test shows a significant difference between the inhibitory zone diameter of these materials (P<0.001). CONCLUSION: The results of this study suggested that curcumin extract did not have any effect on the inhibition of Candida albicans in laboratory environment.

The Effect of Health Promoting Programs on Patient's Life Style After Coronary Artery Bypass Graft-Hospitalized in Shiraz Hospitals.

BACKGROUND: Health promotion is an essential strategy for reduction of health disparities. Health promotion includes all activities that encourage optimum physical, spiritual, and mental functions. The aim of this study was to determine the impact of a Health Promotion Program (HPP) on behavior in terms of the dimensions of the Health Promoting Lifestyle Profile (HPLP) in patients after Coronary Artery Bypass Graft (CABG). METHODS & MATERIALS: In this clinical trial study, 80 patients who had undergone CABG surgery (2011-2012) were selected and randomly divided in two groups: Experimental and Control that investigated by (HPLP II). Then the experimental group was educated about diet, walking and stress management. The program process was followed up for three months and after tward whole variables were investigated again. The overall score and the scores for the six dimensions of the HPLP (self actualization, health responsibility, exercise, nutrition, interpersonal support and stress management) were measured in the pre- and post-test periods. Data were manually entered into SPSS version 21(IBM Corp, USA) by one the authors. Statistical analysis was performed using Student's t-test and paired t-test. Mean standard deviation and standard error of the mean (with 95% Confidence Interval) were generated for each item. RESULTS: Results showed that score of stress management (p=.036), diet (p=.002), Spiritual Growth (p=.001) and interrelationship (p=002) increase in experimental group after intervention. Average scores after three months in the control group had no significant changes; except responsibility for health (p<.05). Results of the study revealed that comparison the scores of the experimental group were significantly different from the control group in all lifestyle aspects except for spiritual growth. CONCLUSION: This study showed that HPP on lifestyle and health promotion in patients who suffered from Coronary Heart Disease (CAD) could improve the patient's awareness of healthy behaviors and well-being in the quality of life.

Insulin Resistance in Patients with Benign Thyroid Nodules.

OBJECTIVE: Recently, it has been questioned whether insulin resistance is associated with thyroid nodules. The aim of this study was to examine insulin resistance prevalence in a case-control study of patients with benign thyroid nodules in an iodine-sufficient area. METHODS: This was a single-center, case-control study on euthyroid patients with benign nodular diseases. Thirty newly diagnosed patients with benign thyroid nodules according to fine needle aspiration cytology were investigated for insulin resistance. As a control group, 30 euthyroid control subjects with normal thyroid sonography without nodule were recruited from the general population. The participants were matched in pairs by age, gender, and body mass index. The diagnosis of insulin resistance was made when the homeostasis model assessment of insulin resistance (HOMA-IR) index was more than 2.5. RESULTS: The mean of HOMA-IR value was significantly higher in patients compared to controls (1.32 ± 0.65 vs. 0.76 ± 0.36, P-value < 0.001). Insulin resistance was seen in two subjects with thyroid nodules (6.7%), but none in the control group. There was a positive significant correlation between HOMA-IR and thyroid nodule size (r-value: +0.38, P < 0.03). CONCLUSION: Patients with thyroid nodules have higher HOMA-IR value. There is an association between insulin resistance and benign thyroid nodules. More investigations are required to define the role of this factor in thyroid nodule formation.