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1.
Khirurgiia (Sofiia) ; (6): 37-9, 2009.
Article in Bulgarian | MEDLINE | ID: mdl-20506778

ABSTRACT

UNLABELLED: Lung cancer is the leading cause for cancer mortality in the men and has an increasing prevalence in the women worldwide. There is growing evidence that the sex is an important prognostic factor for the patients with lung cancer. MATERIAL AND METHODS: We present 440 radically operated patients with non-small cell lung cancer between 1997 and 2004, age range: 23-82 years (378 male- 85.91% and 62 female14.09%). RESULTS: The 5-years survival rate was 26,19% for the men (99 patients) and 51.61% for the female patients (32 patients). CONCLUSIONS: Sex is a significant prognostic factor for the patients with non-small cell lung cancer. Female sex is a good prognostic factor for survival.


Subject(s)
Carcinoma, Non-Small-Cell Lung/diagnosis , Lung Neoplasms/diagnosis , Adult , Aged , Aged, 80 and over , Carcinoma, Non-Small-Cell Lung/surgery , Female , Humans , Lung Neoplasms/surgery , Male , Middle Aged , Prognosis , Sex Factors , Survival Rate , Young Adult
2.
Khirurgiia (Sofiia) ; 59(4): 24-7, 2003.
Article in Bulgarian | MEDLINE | ID: mdl-15641533

ABSTRACT

The mechanisms of development of benign thyroid disease are still not entirely clarified. Immune disorders are possibly engaged in the thyroid pathological conditions. The aim of this prospective study was to follow up the dynamics of serum levels of anti-thyroid antibodies in patients with benign thyroidal disease as well as the local lymphocytic reaction. The autoantibodies to thyroglobulin and thyroid microsomes were detected prior to the surgery and on the 12th month after it using microhemaglutination test. Thyroid resection was performed depending on changes in patients. Lymphocytic infiltration of the thyroid gland from surgical histological specimens was found in various degree in the patients. Serum titres of anti-thyroid antibodies tended to fall in the majority of the patients a year after the surgical treatment. Anti-thyroglobulin antibodies were found in 60% of the patients prior to the surgery and anti-microsomal--in 31.4%. A year after surgery they were detected in 4.3% and 1.4% of the patients respectively. The described changes show that the dynamics of anti-thyroid antibodies may correlate with the effect of surgical treatment and eventual prognosis of relapse.


Subject(s)
Autoantibodies/blood , Thyroid Diseases/immunology , Thyroid Diseases/surgery , Adult , Autoantibodies/immunology , Chemotaxis, Leukocyte , Female , Follow-Up Studies , Humans , Lymphocytes/physiology , Male , Middle Aged , Prospective Studies , Thyroidectomy
3.
Khirurgiia (Sofiia) ; 57(1-2): 54-5, 2001.
Article in Bulgarian | MEDLINE | ID: mdl-12024658

ABSTRACT

Hamartoma is one of the most common benign tumour of the lung. The authors report their results of the surgical treatment of 17 patients with lung hamartoma. Twelve of them underwent open thoracotomy and 5 video-assisted thoracoscopy. Lobectomy was performed in 6 patients, segmentectomy in 3 and patients atypical lung resection in 8. All of the patients did not have complications.


Subject(s)
Hamartoma/surgery , Lung Neoplasms/surgery , Aged , Biopsy , Bulgaria , Female , Humans , Male , Middle Aged , Retrospective Studies , Thoracic Surgery, Video-Assisted/methods , Thoracoscopy/methods , Thoracotomy/methods , Video Recording
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