ABSTRACT
AIM: This study aimed to evaluate the effects of phyto-supplements on hyperlipidemia. METHODS: For this study 191 patients, affected by hyperlipidemia, attending the Outpatient Clinics of Clinical Medicine Department, were recruited. The patients were divided in two groups. The first group (80) has been treated with hypolipidic diet for six months (group D). The second one (111) has been administered with hypolipidic diet and supplement (red yeast, guggulsterones, flavonoid, sylimarin) (group E). Anthropometric measurements and bioimpedance analysis were evaluated before and after treatment. Moreover, total cholesterol, LDL, HDL, triglycerides (TG) and hepatic transaminases (AST, ALT) were measured before, after 3 and 6 months of treatment. RESULTS: D group showed a significant reduction in BMI (32.6 ± 0.7 vs. 34.3 ± 0.7 kg/m²), waist circumference (104.4 ± 1.6 vs. 108.3 ± 1.5 cm), hip circumference (107.9 ± 1.1 vs. 111.2 ± 1.1 cm), total cholesterol (214.2 ± 3.7 vs. 236.6 ± 2.2 mg/dL, -9.4 ± 68.2%), LDL cholesterol (133 ± 3 vs. 152.9 ± 2.8 mg/dL, -13 ± 7.1%). E group showed a significant reduction in BMI (30.2 ± 0.7 vs. 32.6 ± 0.6 kg/m²), waist circumference (94.5 ± 1.6 vs. 101.3 ± 1.3 cm), hip circumference (106.6 ± 1.1 vs. 110.5 ± 1 cm), total cholesterol (212.4 ± 3.7 vs. 256.9 ± 2.1 mg/dL, -17.3 ± 76.2%), LDL cholesterol (133.4 ± 3.4 vs. 168.4 ± 2.3 mg/dL, -20.8 ± 47.8%). CONCLUSION: Low fat diet, associated to phyto-substance supplement, have been proven useful to decrease serum cholesterol level and to improve nutritional status.
Subject(s)
Diet, Reducing , Dietary Supplements , Hypercholesterolemia/diet therapy , Hypercholesterolemia/drug therapy , Phytotherapy , Weight Loss , Body Mass Index , Cholesterol/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Electric Impedance , Female , Follow-Up Studies , Humans , Hypercholesterolemia/blood , Male , Middle Aged , Outpatients , Phytotherapy/methods , Transaminases/blood , Treatment Outcome , Triglycerides/blood , Waist CircumferenceABSTRACT
Deep Brain Stimulation (DBS) has revealed a convincing clinical efficacy in Parkinson's diseases and essential tremor. Unfortunately, to date no clear understanding of the therapeutic mechanisms has been achieved. Characterization of the distribution of the electrical quantities inside the target areas of the central nervous system is one fundamental step ahead. Starting from the studies that so far addressed this issue, aim of this work is to quantify the role of some parameters, such as dimensions of the conducting domain and of boundary conditions, on the distribution of the fundamental electric quantities inside the brain target area.
