ABSTRACT
A study has been made to determine the inhibitory action upon the progress of dental caries of two trace elements (fluorine and molybdenum) combined with chlorohexidine with the goal of increasing the efficiency of fluoride treatment. However, the results obtained show that the chosen combination of trace elements did not lead to a substantial increase in cariostatic action. Combined use of fluorides and chlorohexidine was seen to exert an inhibitory action on the progress of dental caries.
Subject(s)
Chlorhexidine/therapeutic use , Dental Caries/prevention & control , Fluorides/therapeutic use , Animals , Dental Enamel/analysis , Fluorides/analysis , Molybdenum/therapeutic use , Rats , Tooth/analysis , Tooth/metabolismABSTRACT
Experiments on fifty Wistar rats were conducted with the object of studying the incorporation of fluoride into the enamel of molars subsequent to the administration of amine-fluoride-containing caries preventives. - Use of two toothpastes with low fluoride contents of 0.125% and 0.18% F, respectively, and two higher-fluoride (1% F) solutions resulted in a marked increase in the concentration of fluoride in the superficial layers of dental enamel.
Subject(s)
Cariostatic Agents/therapeutic use , Dental Caries/prevention & control , Fluorides/analysis , Molar/analysis , Animals , Calcium/analysis , Dental Enamel/analysis , Diet, Cariogenic , Rats , Time FactorsSubject(s)
Bone and Bones/metabolism , Calcium/metabolism , Space Flight , Tooth/metabolism , Animals , Phosphorus/metabolism , Rats , Time Factors , USSRABSTRACT
Examinations of 37 rats flow for 22 days onboard the biosatellite Cosmos-605 revealed no changes in the mineralization coefficient or the Ca and P content in humerus and teeth of the animals on the 2nd and 26th postflight days. Radioisotope studies showed changes in the specific activity of Ca45 incorporation in humerus and incisors. In flight rats the parameter decreased by 37-44%, in synchroneous animals it increased by 102% in bones and by 20% in incisors as compared with the vivarium controls on the 2nd postflight day. The specific activity of Ca45 incorporation was 92.7% in humerus and 44.2% in incisors of flight rats and 72.9% in humerus and 94.7% in incisors of synchroneous rats as compared with the vivarium controls on the 26th postflight day.