ABSTRACT
The comparative study of the main characteristics of immune status in patients with urogenital chlamydiosis, furunculosis, urogenital herpes (38 patients) and in the members of the control group (21 subjects) was made. The analysis of the results obtained in this study revealed the numerical values of immunological characteristics, capable of being used as markers indicating transition into the chronic form. Thus, it showed a decrease in the population of cells with phenotype CD72+ in chlamydiosis; a fourfold increase in the population of cells with phenotype CD16+ in furunculosis; an increase in the population of cells with phenotype CD8+, a decrease in the immunoregulatory index and the population of cells with phenotype CD72+ in herpes. The data thus obtained may be used in prescribing immunocorrective therapy.
Subject(s)
Female Urogenital Diseases/immunology , Furunculosis/immunology , Immunity/physiology , Male Urogenital Diseases , Probability , Antigens, CD/blood , Biomarkers/blood , Chlamydia Infections/immunology , Chronic Disease , Herpes Genitalis/immunology , Humans , Phenotype , PrognosisABSTRACT
Changes in the values of the immune status during UV autohemotherapy were studied in 22 patients with surgical endotoxicosis of various genesis. Maximum tension of immunogenesis was found in all patients. The time course of changes in the general pool of rosette-forming and separate populations of neutrophils, as well as in the index of immunocompetent cell ratios are evidence of the high informativeness of these tests in determining the severity of the immune system dysfunctions.
Subject(s)
B-Lymphocytes/immunology , Blood/radiation effects , Cholecystitis/immunology , Endotoxins/blood , Peritonitis/immunology , T-Lymphocytes/immunology , Toxemia/immunology , Ultraviolet Therapy , Adult , Aged , B-Lymphocytes/radiation effects , Cholecystitis/blood , Cholecystitis/surgery , Endotoxins/radiation effects , Humans , Leukocyte Count/radiation effects , Middle Aged , Peritonitis/blood , Peritonitis/surgery , Preoperative Care , T-Lymphocytes/radiation effects , Toxemia/etiology , Toxemia/radiotherapySubject(s)
B-Lymphocytes/immunology , Immunoglobulins/analysis , Kidney Failure, Chronic/immunology , Adolescent , Adult , Female , Humans , Lymphopenia/etiology , Male , Middle AgedABSTRACT
A study was made of the effect of heparin on the capacity of the human blood lymphocytes to blast-transformation in response to the stimulation with antilymphocytic gamma-globulin and phytohemagglutinin. Heparin proved to inhibit more intensively the transformation of lymphocytes stimulated by the antilymphocytic gamma globulin. The depressive effect arose when heparin was injected one hour before the mitogen, simultaneously with it and one hour after it.
