ABSTRACT
The causative agents of typhoid fever isolated in 1990 in the Soviet Union were mainly sensitive to ampicillin, tetracyclines and streptomycin and slightly sensitive to rifampicin and gentamicin. The number of the strains resistant to rifampicin and gentamicin is ever increasing. The strains of Salmonella typhi isolated in the Soviet Union were sensitive to chloramphenicol unlike the strains isolated in India which were characterized by high resistance to this antibiotic. The phage type pattern of the isolates was mainly represented by the phage types A1 (57.5 per cent) and B1 (30.8 per cent). No relation between separate phage types of S. typhi and their antibiotic resistance phenotypes was detected.
Subject(s)
Bacteriophage Typing , Salmonella typhi/drug effects , Drug Resistance, Microbial/genetics , Humans , India , Microbial Sensitivity Tests , Phenotype , Salmonella typhi/classification , Salmonella typhi/isolation & purification , Species Specificity , USSRABSTRACT
As many as 94 patients with yersiniosis were examined for the morphofunctional status of platelets (aggregation, disaggregation, endo-exocytosis and platelet forms). The data indicate that platelet from patients with yersiniosis possess a high ability for aggregation and a low ability for disaggregation. According to the experimental and clinical data, emoxipine can restore disturbed function of human platelets.
Subject(s)
Fibrinolytic Agents/therapeutic use , Picolines/therapeutic use , Platelet Aggregation Inhibitors/therapeutic use , Platelet Aggregation/physiology , Thrombosis/etiology , Yersinia Infections/blood , Yersinia enterocolitica , Yersinia pseudotuberculosis Infections/blood , Culture Media , Fibrinolytic Agents/pharmacology , Humans , In Vitro Techniques , Lipopolysaccharides/physiology , Picolines/pharmacology , Platelet Aggregation/drug effects , Platelet Aggregation Inhibitors/pharmacology , Thrombosis/drug therapy , Yersinia Infections/complications , Yersinia Infections/microbiology , Yersinia enterocolitica/metabolism , Yersinia pseudotuberculosis Infections/complicationsABSTRACT
Clinical and laboratory evaluation of arthritis in 36 children with diagnosed enteric yersiniosis is presented on seven-years' follow-up data. Twenty-eight patients were found to have an active course of the disease developing in cycles with a favourable outcome and no residual effects. In eight cases arthritis took a protracted (up to 8-10 months) or chronic (over 12 months) course which ended in clinical and laboratory remission; in three of the eight cases the clinical picture was similar to that of rheumatoid arthritis, in two of which the diagnosis was not excluded by the morphological study of the synovial biopsy sample.
