ABSTRACT
Piperacillin/tazobactam, at a dosage of 4 g/500 mg every 8 h, was administered intravenously to 217 patients with complicated urinary tract infections. The most common diagnosis was pyelonephritis. The most common pathogen was Escherichia coli (47%) followed by Pseudomonas aeruginosa (13%), and enterococci (8%). Among clinically evaluable patients, 86% (115/134) were cured or improved at the study endpoint and 14% (19/134) were clinical failures or relapsed. Among bacteriologically evaluable patients, 85% (95/112) had a favorable clinical response at endpoint. The bacteriological response rate was 73% (82/112) at endpoint. Overall, 82% of all pathogens were eradicated. Therapy was associated with a low incidence of side effects, and adverse experience were mild and of short duration.
Subject(s)
Bacterial Infections/drug therapy , Penicillanic Acid/analogs & derivatives , Piperacillin/therapeutic use , Urinary Tract Infections/drug therapy , beta-Lactamase Inhibitors , Bacterial Infections/complications , Drug Combinations , Female , Follow-Up Studies , Humans , Male , Middle Aged , Penicillanic Acid/adverse effects , Penicillanic Acid/therapeutic use , Piperacillin/adverse effects , Recurrence , Remission Induction , Tazobactam , Urinary Tract Infections/complicationsSubject(s)
Endoscopy , Ureteral Obstruction/diagnosis , Adult , Aged , Female , Humans , Methods , Middle Aged , Ureteral Obstruction/therapyABSTRACT
An inquiry organized by the Belgian Society of Surgery brought data on the mortality and morbidity of surgery on patients of 80 years and older for benign prostatic hypertrophy in a total number of 1,140 operations. Consensus exist to see this surgery as planned surgery. The mortality was 73 (6.3%) without statistical difference between endoscopic and open surgery. The morbidity of 824 patients was 165. This last figure relates to the big series in the literature. The mortality is in direct relation to the age of the patients. Evaluation of cardio-pulmonary risk (70.8% of the mortality), operation on indication at earlier diagnosis and prospective studies on the risk of operation in this population group are indicated.
Subject(s)
Prostatic Hyperplasia/surgery , Aged , Belgium , Humans , Male , Postoperative Complications/mortality , Prostatic Hyperplasia/mortality , Retrospective Studies , RiskSubject(s)
Urethral Stricture/surgery , Adult , Aged , Endoscopy , Follow-Up Studies , Humans , Male , Methods , Middle AgedSubject(s)
Castration , Prostatic Neoplasms/therapy , Aged , Humans , Male , Middle Aged , Testosterone/bloodABSTRACT
The superior diagnostic contribution of bladder washing as compared to routine urinary cytology was demonstrated in a prospective study. Random mucosal biopsies of normal-looking mucosa taken at the time of treatment or of the first control cystoscopy revealed the presence of multiple cancerous or precancerous lesions in a variety of patients. The heterogeneity of bladder cancer had to be recognized for adequate follow-up and treatment.
