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1.
Stomatol DDR ; 27(10): 640-5, 1977 Oct.
Article in German | MEDLINE | ID: mdl-270851

ABSTRACT

The protein-producing function of the odontoblasts was studied in 120 Wistar rats with an initial weight ranging from 30 to 40 g determining the rate of the migration of radio-active isotopes (glycine-2-14C, lysine-1-14C) from the odontoblasts to the predentine. The odontoblasts exert a protein-synthetizing function and play an active part in predentine formation. Under the influence of a cariogenic saccharose-casein diet and the simultaneous induction of experimental caries, the intensity of the migration of the labelled amino acids from the odontoblasts to the predentine increases during the first and second stages of caries, which must be interpreted as an increase of the protein-synthetizing function of the odontoblasts associated with an intensification of dentinogenesis. During the third stage of caries, the protein-producing function of the odontoblasts decreases.


Subject(s)
Odontoblasts/metabolism , Protein Biosynthesis , Animals , Autoradiography , Dental Caries/metabolism , Dentinogenesis , Diet, Cariogenic , Rats
2.
Zahn Mund Kieferheilkd Zentralbl ; 65(2): 186-90, 1977.
Article in German | MEDLINE | ID: mdl-141180

ABSTRACT

Experimental animal studies were made in an attempt to determine by means of series of sections the anticarious properties and effects of a locally applied mineral solution in the presence and absence of fluorides


Subject(s)
Dental Caries/prevention & control , Fluorides, Topical/administration & dosage , Minerals/administration & dosage , Animals , Diet, Cariogenic , Fluoridation , Male , Rats
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