Subject(s)
Analgesia/methods , Diabetes Mellitus, Type 2/complications , Diabetic Neuropathies/complications , Neuralgia/etiology , Neuralgia/therapy , Aged , Amitriptyline/administration & dosage , Analgesics, Non-Narcotic/administration & dosage , Bone and Bones , Combined Modality Therapy , Female , Humans , Male , Middle Aged , Neuralgia/drug therapy , SyndromeABSTRACT
AIM: To elucidate relationships brain-heart in hemorrhagic stroke depending on the size and location of hematoma and initial state of the heart. MATERIAL AND METHODS: Clinical and paraclinical methods were used in acute and rehabilitation periods in 160 patients with hemorrhagic stroke. RESULTS: Symptoms of cerebrocardial syndrome in hemorrhagic stroke include arrhythmias (tachycardia, bradycardia, extrasystole, cardiac fibrillation, sick sinus syndrome), blocks (transient bundle-branch block), myocardial dystrophy, in IHD--ischemic myocardial disorders up to subendocardial myocardial infarction. Its severity in massive hemispherical hematomas was due to compression of the brain trunk. CONCLUSION: Pathogenesis of cerebrocardial syndrome rests on impaired central autonomic regulation occurring in stroke.
Subject(s)
Cardiomyopathies/etiology , Intracranial Hemorrhages/complications , Intracranial Hypertension/etiology , Stroke/complications , Adult , Aged , Aged, 80 and over , Cardiomyopathies/pathology , Echocardiography , Electrocardiography , Electroencephalography , Female , Humans , Intracranial Hemorrhages/pathology , Intracranial Hemorrhages/physiopathology , Intracranial Hypertension/pathology , Magnetic Resonance Imaging , Male , Middle Aged , Stroke/pathology , Stroke/physiopathology , Tomography, X-Ray ComputedABSTRACT
AIM: To study nervous systems in chronic adrenal failure (CAF). MATERIAL AND METHODS: 262 patients with CAF were studied clinically, biochemically and electrophysiologically before and after treatment. RESULTS: The patients were found to have syndromes of vegetovascular dystonia by hypotonic type, syncopal paroxysms, myastenic, minor strokes, dyscirculatory-dysmetabolic encephalopathy, polyneuropathy. A direct correlation was established between the severity and duration of adrenal failure (AF), lowering of adrenal cortex hormones, coefficient Na/K and clinical manifestations of the neurological syndromes. Adequate hormone replacing and symptomatic therapy promoted a regress of neurological disorders in most of the patients especially in mild and moderate AF. CONCLUSION: Adequate therapy corrects neurological disturbances in patients with chronic NN.
Subject(s)
Adrenal Insufficiency/complications , Central Nervous System/physiopathology , Nervous System Diseases/physiopathology , Adolescent , Adrenal Cortex Hormones/blood , Adrenal Insufficiency/blood , Adrenal Insufficiency/physiopathology , Adult , Aged , Child , Chronic Disease , Disease Progression , Female , Humans , Male , Middle Aged , Nervous System Diseases/etiology , PrognosisABSTRACT
AIM: To study the role of autonomic nervous system (ANS) in pathogenesis and clinical symptoms of arterial hypertension (AH) in Icenko-Cushing disease (ICD). MATERIALS AND METHODS: Clinical and paraclinical parameters (vegetative reflexes, special tables, 10 words memory and Spilberg's tests, ECG, electroencephalography, computed tomography, MR-tomography, hormonal status) were studied in 48 ICD patients before and after treatment (adenomectomy, irradiation of the hypophysis, adrenalectomy, parlodel, chlotidin chemotherapy). RESULTS: 94.5% of patients with active ICD had blood hypertension and vegetovascular asthenia. There was a trend to cerebrovascular impairment. In spite of biochemical and clinical ICD remission lipothemia persisted in many patients. CONCLUSION: Pathogenesis of blood hypertension in ICD is related to hypersecretion of ACTH and corticosteroids but further progress of the disease depends on phenotypic features of autonomic nervous system and developing defects of CNS.
Subject(s)
Autonomic Nervous System , Cushing Syndrome/complications , Hypertension/etiology , Adolescent , Adult , Asthenia/complications , Asthenia/physiopathology , Autonomic Nervous System/physiopathology , Blood Pressure , Cushing Syndrome/blood , Cushing Syndrome/diagnosis , Electroencephalography , Female , Follow-Up Studies , Humans , Hydrocortisone/blood , Hypertension/physiopathology , Magnetic Resonance Imaging , Middle Aged , Reflex, Abnormal , Tomography, X-Ray ComputedABSTRACT
Biomicroscopy of bulbar conjuctiva as well as oencephalography were quite informative for discovery of subclinical manifestations of disorders of cerebral circulation (DCC). That conclusion resulted from the observation of 133 patients with early forms of vascular pathology of brain. Besides, to find the early signs, it was also worth while to perform some biochemical studies (coagulogram, studies of both rheologic properties and lipids of blood). In order to establish discirculatory encephalopathy it was also expedient to use ultrasonic dopplerography and electroencephalography. Efficiency of some medical-prophylactic measures (normalization of the diet, weight, muscular activity, administration of antiatherosclerotic drugs) that prevented the progression of aorta's stenosis was also demonstrated.
Subject(s)
Cerebrovascular Disorders , Adult , Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/prevention & control , Cerebrovascular Disorders/therapy , Female , Humans , Lipids/blood , Male , Middle Aged , Triglycerides/bloodABSTRACT
Neurological, clinical, biochemical examinations, electroencephalography, computer and magnetic resonance tomography of the brain of 336 patients with brain stem and para-brain stem tumors resulted in conclusion that nonspecific autonomic-endocrine reaction caused by disorders in central regulation was the main component of early postoperative period. The first type of such disorders included cases with rather stable indices of both hemodynamics and ionic-osmotic homeostasis characterized by favourable course. Unstable hemodynamics and tendency to increase of osmolarity and serum levels of sodium and glucose as well as unfavourable course of this period were typical for the second type.
