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Relationship between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn.

Archambault, Jamie L; Hernandez, Teri L; Nozik, Eva S; Palmer, Claire; Dillon, Mairead; Singh, Ravinder J; Galambos, Csaba; Delaney, Cassidy A.

J Pediatr ; 276: 114290, 2024 Sep 04.

Article in English | MEDLINE | ID: mdl-39242076

ABSTRACT

Urine serotonin (5-HT)/creatinine was lower at day of life 3 in newborns with pulmonary hypertension compared with controls, while the percent change in the 5-HT metabolite, 5-hydroxyindoleacetic acid (5-HIAA)/creatinine increased. We speculate that the changes in 5-HT and 5-HIAA reflect enhanced pulmonary 5-HT uptake and/or metabolism.

Implementation of a Rapid Evidence Assessment Infrastructure during the Coronavirus Disease 2019 (COVID-19) Pandemic to Develop Policies, Clinical Pathways, Stimulate Academic Research, and Create Educational Opportunities.

Rao, Suchitra; Kwan, Bethany M; Curtis, Donna J; Swanson, Angela; Bakel, Leigh Anne; Bajaj, Lalit; Boguniewicz, Juri; Lockwood, Justin M; Ogawa, Kaleigh; Pemberton, Katherine; Fuhlbrigge, Robert C; Brumbaugh, David; Givens, Patricia; Nozik, Eva S; Sills, Marion R.

J Pediatr ; 230: 4-8.e2, 2021 03.

Article in English | MEDLINE | ID: mdl-33091418

Subject(s)

Advisory Committees/organization & administration , COVID-19/epidemiology , Translational Research, Biomedical/organization & administration , Colorado/epidemiology , Critical Pathways , Humans , Information Dissemination , Interprofessional Relations , Needs Assessment , Pandemics , Program Evaluation , Quality Improvement

ABSTRACT

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