ABSTRACT
It has been suggested earlier that the serum Mg value cannot be considered as a reliable index indicating the body Mg status and that pigs may suffer from Mg deficiency despite the fact that the food Mg content is distinctly higher than the requirement level given by the Agricultural Research Council and National Research Council. In this study the effect of the food Mg level on the serum Mg value was more widely investigated and, simultaneously, the effect of the food Mg level on the serum Mg:Ca and K value was studied. Bone Mg contents were also determined to make sure in which groups the pigs had suffered from Mg deficiency.
Subject(s)
Animal Feed/analysis , Magnesium/blood , Swine/blood , Animals , Bone and Bones/analysis , Calcium/blood , Magnesium Deficiency/blood , Magnesium Deficiency/veterinary , Potassium/blood , Swine Diseases/bloodABSTRACT
1. Pigs were fed on semi-purified food. The magnesium content of the experimental diet was 1.0 and that of the control diet 1.9 g/kg. 2. In the low-Mg group serum triglycerides and blood lactate values were increased and base excess and standard bicarbonate values were decreased, indicating metabolic acidosis. 3. A significant positive dependence was found between blood pH and serum Mg:Ca value as well as between blood pH and serum Mg, and also between body temperature and blood lactate values in the low-Mg group. None of these dependences was significant in the control group with magesium acetate supplementation in the food. 4. No specific histopathological changes were found in heart, liver or kidney of the experimental animals. 5. The results indicate that an increase in serum triglycerides does not need to depend on the amount of quality of food fat. 6. The present study shows that, in pigs, a low-Mg diet may cause metabolic disturbances in instances with the food Mg content is distinctly higher than the normal values recommended by the (UK) Agricultural Research Council (1966) and (US) National Research Council (1968).
Subject(s)
Diet , Magnesium Deficiency/metabolism , Magnesium/administration & dosage , Animals , Carbon Dioxide/blood , Hydrogen-Ion Concentration , Lactates/blood , Magnesium/blood , Partial Pressure , Pyruvates/blood , Swine , Triglycerides/bloodABSTRACT
The interrelationships between serum Mg and HCR, and between serum Mg and K were investigated in pigs fed on a low Mg diet. A positive dependence was found between serum Mg and HCR, and between serum Mg and K. It was concluded, that in Mg-deficient pigs, Mg ions originating from soft tissues or erythrocytes can cause an increase of serum Mg level. The serum Mg value, consequently, can not be considered as a reliable parameter indicating the body Mg status. Some difficulties in diagnosing the body Mg status and the effects of the spontaneous increase of serum Mg level on Mg deficiency symptoms were discussed.
Subject(s)
Magnesium Deficiency/veterinary , Magnesium/blood , Swine Diseases/blood , Animals , Erythrocytes/metabolism , Magnesium Deficiency/blood , Potassium/blood , SwineABSTRACT
Studies were made to investigate the effect of food Mg level on ALAT, ASAT, LD and BASP values in pigs. The following conclusions were drawn:--a high food Mg level (0.31% in ordinary pig food) can cause an increase in serum BASP values.--leg weakness, at the primary stage, is hardly caused by disturbances in bone.--an ordinary diet low in Mg may cause an abnormal rise in ALAT values in pigs.--when feeding pigs on an ordinary diet, pigs may suffer from Mg deficiency despite the fact that the food Mg content is distinctly higher than that recommended by international norms for feeding.--a prompt lowering of food Mg level can cause a manifest increase in ASAT, LD and BASP values within 2 to 3 days in pigs. Heart and liver injuries caused by low Mg diets and the individual ability of pits to utilize magnesium were discussed.
