ABSTRACT
Bleeding, the most frightening adverse effect of anticoagulants,may occur in different parts of the body.When intracerebral hemorrhage in individuals used anticoagulant drugs is compared with normal coagulation function, the volume of bleeding is increased and the prognosis is worse. There are few studies in the literature regarding the presence of intracerebral hemorrhage and the volume and prognosis of bleeding associated with rivaroxaban, a new oral anticoagulant.Therefore, the clinical and radiologic findings and follow-up of an 80-year-old male patient with intracerebral hemorrhage who uses rivaroxaban for anticoagulation are presented in this article.
Subject(s)
Cerebral Hemorrhage/chemically induced , Factor Xa Inhibitors/adverse effects , Morpholines/adverse effects , Thiophenes/adverse effects , Aged, 80 and over , Humans , Male , RivaroxabanABSTRACT
Whiplash Associated Disorders (WAD) has been reported as an adult phenomenon. Whiplash injury has classically been described as a cervical soft tissue hyperextension- flexion injury after a trauma such as a rear end impact car crash, contact sport injuries, blows to the head from a falling object or a punch and shaken baby syndrome and is mostly seen in adults . It is important as it may cause severe disability due to spinal cord injury, decrease work productivity and even retropharyngeal hematoma resulting airway obstruction and mortality due to bleeding amongst deep cervical fascias. We describe a case of retropharyngeal hematoma after whiplash injury in a childhood.
Subject(s)
Hematoma/etiology , Pharynx/injuries , Whiplash Injuries/complications , Accidents, Traffic , Cervical Vertebrae/pathology , Child, Preschool , Edema/etiology , Edema/pathology , Hematoma/diagnostic imaging , Hematoma/pathology , Humans , Magnetic Resonance Imaging , Male , Neck Pain/etiology , Neurologic Examination , Pharynx/diagnostic imaging , Pharynx/pathology , Tomography, X-Ray Computed , Ultrasonography , Whiplash Injuries/diagnostic imaging , Whiplash Injuries/pathologyABSTRACT
INTRODUCTION: Aplasia cutis congenita (ACC), is a rare anomaly presenting with a solitary scalp lesion of skin abrasion. Lesions can be multiple and on different surfaces of the body but are mostly seen on the scalp (%70) as a solitary lesion. As it is a rare disease, we aimed to describe our case with ACC. CASE REPORT: Our case was a newborn infant with a large full thickness skin and skull defect on the scalp at birth. He also had hypoplasia on the fingers, omphalocele, ectopic anus, cleft lip and palate anomalies and multiple cardiac anomalies. We planned further evaluation but he died 23 hours after birth because of cardiac problems. DISCUSSION: Multiple factors have been described as etiological factors for ACC but the etiology is not clear yet. ACC may also be associated with some syndromes. Management strategies are based on the size, presence of an underlying skull defect and the child's physical condition.
Subject(s)
Ectodermal Dysplasia/complications , Nervous System Malformations/complications , Skull/abnormalities , Anal Canal/abnormalities , Fatal Outcome , Humans , Infant, Newborn , Male , Urinary Bladder/abnormalitiesABSTRACT
We conducted a study to determine the effectiveness of topically applied recombinant mouse fibroblast growth factor-2 (FGF-2) in healing the dura mater in a rat with dura mater injury and cerebrospinal fluid leakage. Laminectomies were performed in 32 rats at the level of the L2-L4 vertebrae, and a dura mater defect was created. Sixteen rats were treated postoperatively with locally applied recombinant mouse FGF-2, and 16 animals received normal saline. FGF-2 effects on dura mater healing, cerebrospinal fluid leakage, and wound healing were assessed at 3 and 6 weeks postoperatively. The extent of dura mater healing was evaluated by histological analysis. We found that dura mater healing was significantly increased (p<0.05) in rats treated with FGF-2 compared with rats in the control group. In this experimental model, locally applied FGF-2 effectively increased dura mater healing and induced no side effects.
