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Ophthalmic Res ; 43(4): 169-72, 2010.
Article in English | MEDLINE | ID: mdl-20068368

ABSTRACT

PURPOSE: The objective of this study was to investigate the antioxidant/oxidant status of serum in patients with pseudoexfoliation syndrome (PEX). METHODS: Forty-seven patients with PEX and 32 healthy controls were included in the study. Serum total antioxidant capacity (TAC) and total oxidant status (TOS) levels were determined by using a novel automated method. RESULTS: A significant increase in serum TOS (p < 0.001) and a significant decrease in serum TAC (p < 0.0001) were observed in PEX patients compared to control subjects. CONCLUSION: TAC decreases while the oxidative stress increases in PEX.


Subject(s)
Antioxidants/metabolism , Biomarkers/blood , Exfoliation Syndrome/blood , Oxidants/blood , Oxidative Stress , Aged , Case-Control Studies , Female , Humans , Intraocular Pressure , Male , Prospective Studies , Tonometry, Ocular
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