ABSTRACT
UNLABELLED: Pathological skeletal muscle weakness is an axial clinical symptom of myasthenia (MG). Diminished respiratory muscular force can be manifested by decreased peak expiratory flow (PEF) value. MATERIAL AND METHODS: Patients aged 13-77 years were studied at which according to Osserman classification ocular form (the type I) or generalized form (the type II) was diagnosed (n = 68). PEF and FVC values such as % of predicted value (PV) obtained in "flow-volume" measure were analysed. The trunk and extremities muscles force was estimated according to Besinger. RESULTS: Weakness of lower extremities muscles was found at all examined subjects. Positive result of trunk muscle test was found in 69% of patients with type I and 89% with type II. In type II upper extremities muscles (UEM) weakness was observed more often than in type I (74% subjects vs. 31%). In both types of MG the mean value of PEF was lower in patients with UEM weakness and amounted 89.5% vs. 112.4% in type I and 87.4% vs. 100.4% in type II. In type I the mean value of FVC was lower in patients with UEM weakness than in patients without symptoms (83.7% vs. 106.2%), with trunk muscles weakness (93.8% vs. 111.7%) and in patients with decreased muscles force up to 15% (87.5% vs. 106.7%). In this type of MG decreased value of FVC < 80% PV was observed in 50% of patients with UEM weakness and in 40% of patients with decreased muscles force up to 15%, but at none of subjects without symptoms in above tests. CONCLUSIONS: In patients with myasthenia of type I and II the weakness of upper extremities muscles correlates with decreased PEF value in spirometry. In addition in ocular myasthenia decreased FVC value was observed more often in patients with positive results of test of the functional muscles estimation.
Subject(s)
Exercise , Myasthenia Gravis/diagnosis , Myasthenia Gravis/physiopathology , Spirometry , Adolescent , Adult , Aged , Female , Forced Expiratory Volume , Humans , Male , Middle Aged , Muscle, Skeletal/physiopathology , Peak Expiratory Flow Rate , Predictive Value of Tests , Respiratory Muscles/physiopathology , Severity of Illness Index , Vital CapacityABSTRACT
This paper overviews the problem of the clinical basis, diagnosis and available therapy modalities for lymphoedema. Regarding diagnostics, the measurement of circumference, volume and thickness of the limb are presented, as well as diagnostic imaging modalities. These include direct and indirect lymphography, MRI, CT, ultrasound imaging and lymphoscintigraphy, which is currently considered the leading technique in primary diagnosis of lymphoedema and its follow-up. This paper discusses the treatment of lymphoedema and the role of lymphoscintigraphy in the follow-up of patents with lymphoedema.
Subject(s)
Lymphedema/diagnostic imaging , Lymphedema/diagnosis , Radionuclide Imaging/methods , Diagnostic Imaging/methods , Electric Impedance , Female , Follow-Up Studies , Humans , Lymph Nodes/pathology , Lymphography/methods , Magnetic Resonance Imaging/methods , Male , Physical Therapy Modalities , Tomography, X-Ray Computed/methods , Ultrasonics , WaterABSTRACT
Myasthenia Gravis (MG) is a primary disorder of neuromuscular transmission, and patients suffering from this disease manifest specific, progressive weakness of several groups of skeletal muscles. Myoadenylate deaminase deficiency (MADD) is an inborn disease of skeletal muscles, the clinical symptoms of which may mimic symptoms observed in MG. Preliminary results of studies presented in this paper suggest that simultaneous occurrence of MG and MADD may modify energetic metabolism of skeletal muscle.
Subject(s)
AMP Deaminase/deficiency , Exercise , Muscle, Skeletal/enzymology , Myasthenia Gravis/enzymology , Adolescent , Adult , Exercise Test , Female , Humans , Male , Muscle, Skeletal/pathology , Myasthenia Gravis/genetics , Myasthenia Gravis/physiopathology , Neuromuscular Diseases/enzymologyABSTRACT
The aim of this study was to evaluate the results of surgical treatment of cubital tunnel syndrome (CTS) and asses the efficiency of surgical techniques implemented in our Department. Fifty-one patients with CTS were treated with 3 different surgical techniques: submuscular transposition, anterior transposition, and ulnar nerve decompression (UND). Thirty-one patients were evaluated post-op: 4 patients after ST, 21 patients after AT and 7 after UND. UND relieves the pain, but numbness, paresthaesia, and decreased muscle power were observed post-op. Post-op tenderness and hyperaesthesia of the medial epicondyle were noted after AT procedures. A decrease in nerve conduction in EMG studies is probably the best quantitation method of ulnar nerve neuropathies. Our study did not indicate which surgical technique was most effective in the treatment of CTS.
