Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Publication year range
2.
BMJ Open ; 4(11): e005798, 2014 Nov 26.
Article in English | MEDLINE | ID: mdl-25428629

ABSTRACT

OBJECTIVE: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disability pension in young patients with chronic fatigue syndrome (CFS). DESIGN: Longitudinal cohort study. INTERVENTION: A written self-management programme including a description of active coping strategies for daily life was provided. SETTING, PARTICIPANTS: Patients with CFS after mononucleosis were evaluated at Department of Neurology, Haukeland University Hospital during 1996-2006 (contact 1). In 2009 self-report questionnaires were sent to all patients (contact 2). PRIMARY AND SECONDARY OUTCOME MEASURES: Primary measure was employment status at contact 2. Secondary measures included clinical symptoms, and Fatigue Severity Scale (FSS) scores on both contacts, and Work and Social Adjustment Scale (WSAS) at contact 2. RESULTS: Of 111 patients at contact 1, 92 (83%) patients returned the questionnaire at contact 2. Mean disease duration at contact 1 was 4.7 years and at contact 2 11.4 years. At contact 1, 9 (10%) were part-time or full-time employed. At contact 2, 49 (55%) were part-time or full-time employed. Logical regression analysis showed that FSS≥5 at contact 2 was associated with depression, arthralgia and long disease duration (all at contact 1). CONCLUSIONS: About half of younger patients with CFS with long-term incapacity for work experienced marked improvement including full-time or part-time employment showing better outcomes than expected. Risk factors for transition to permanent disability were depression, arthralgia and disease duration.


Subject(s)
Employment/statistics & numerical data , Fatigue Syndrome, Chronic/epidemiology , Infectious Mononucleosis/epidemiology , Return to Work/statistics & numerical data , Activities of Daily Living , Adaptation, Psychological , Adult , Cohort Studies , Comorbidity , Disabled Persons/statistics & numerical data , Female , Follow-Up Studies , Humans , Longitudinal Studies , Male , Norway/epidemiology , Risk Factors , Self Care/statistics & numerical data , Severity of Illness Index , Socioeconomic Factors , Surveys and Questionnaires , Young Adult
3.
BMC Gastroenterol ; 12: 13, 2012 Feb 08.
Article in English | MEDLINE | ID: mdl-22316329

ABSTRACT

BACKGROUND: A waterborne outbreak of Giardia lamblia gastroenteritis led to a high prevalance of long-lasting fatigue and abdominal symptoms. The aim was to describe the clinical characteristics, disability and employmentloss in a case series of patients with Chronic Fatigue Syndrome (CFS) after the infection. METHODS: Patients who reported persistent fatigue, lowered functional capacity and sickness leave or delayed education after a large community outbreak of giardiasis enteritis in the city of Bergen, Norway were evaluated with the established Centers for Disease Control and Prevention criteria for CFS. Fatigue was self-rated by the Fatigue Severity Scale (FSS). Physical and mental health status and functional impairment was measured by the Medical Outcome Severity Scale-short Form-36 (SF-36). The Hospital Anxiety and Depression Scale (HADS) was used to measure co-morbid anxiety and depression. Inability to work or study because of fatigue was determined by sickness absence certified by a doctor. RESULTS: A total of 58 (60%) out of 96 patients with long-lasting post-infectious fatigue after laboratory confirmed giardiasis were diagnosed with CFS. In all, 1262 patients had laboratory confirmed giardiasis. At the time of referral (mean illness duration 2.7 years) 16% reported improvement, 28% reported no change, and 57% reported progressive course with gradual worsening. Mean FSS score was 6.6. A distinctive pattern of impairment was documented with the SF-36. The physical functioning, vitality (energy/fatigue) and social functioning were especially reduced. Long-term sickness absence from studies and work was noted in all patients. CONCLUSION: After giardiasis enteritis at least 5% developed clinical characteristics and functional impairment comparable to previously described post-infectious fatigue syndrome.


Subject(s)
Absenteeism , Disability Evaluation , Enteritis/complications , Enteritis/parasitology , Fatigue Syndrome, Chronic/epidemiology , Giardia/isolation & purification , Giardiasis/complications , Adult , Anxiety/epidemiology , Anxiety/psychology , Depression/epidemiology , Depression/psychology , Fatigue Syndrome, Chronic/psychology , Female , Humans , Incidence , Male , Norway , Retrospective Studies , Severity of Illness Index , Time Factors
SELECTION OF CITATIONS
SEARCH DETAIL
...