ABSTRACT
Godinho investigates the role centrosomes play in cancer cell biology.
Subject(s)
Cell Biology/trends , Centrosome , Neoplasms/genetics , Spindle Apparatus/genetics , Cell Biology/history , History, 21st Century , Humans , Microtubules/geneticsABSTRACT
Song investigates the mechanisms that control stem cell fate in development and disease.
Subject(s)
Cell Differentiation , Cell Lineage , Drosophila Proteins/metabolism , Drosophila melanogaster/growth & development , Neural Stem Cells/cytology , Animals , Drosophila Proteins/genetics , Drosophila melanogaster/genetics , History, 21st Century , Humans , Neural Stem Cells/metabolism , Time-Lapse ImagingABSTRACT
Lazarou investigates the relationship between mitochondria and autophagy.
Subject(s)
Autophagy/physiology , Biology/history , Mitochondria/physiology , Animals , Australia , History, 21st Century , HumansABSTRACT
Maeshima investigates the higher order structures and dynamics of chromatin.
Subject(s)
Chromatin/metabolism , Humans , Microscopy , Nucleosomes/metabolismABSTRACT
Tripathi investigates how the tumor suppressor DLC1 is regulated by oncogenic kinases.
Subject(s)
Antineoplastic Agents/pharmacology , GTPase-Activating Proteins/antagonists & inhibitors , Neoplasms/drug therapy , Phosphotransferases/antagonists & inhibitors , Translational Research, Biomedical , Tumor Suppressor Proteins/antagonists & inhibitors , GTPase-Activating Proteins/genetics , GTPase-Activating Proteins/metabolism , Humans , Neoplasms/metabolism , Neoplasms/pathology , Phosphotransferases/metabolism , Tumor Suppressor Proteins/genetics , Tumor Suppressor Proteins/metabolismABSTRACT
Rivera-Serrano investigates the host cell genes that support viral infection.
Subject(s)
Research Personnel , Virology/history , History, 20th Century , History, 21st Century , HumansABSTRACT
Alushin investigates the structural biology of biomechanical processes in the cytoskeleton.
Subject(s)
Actin Cytoskeleton/ultrastructure , Actins/ultrastructure , Cytoskeleton/ultrastructure , Microfilament Proteins/ultrastructure , Actins/chemistry , Biomechanical Phenomena , Cryoelectron Microscopy , Cytoskeleton/chemistry , Humans , Microfilament Proteins/chemistry , Molecular StructureABSTRACT
Saito studies the mechanisms that control secretion of collagen from the ER.
Subject(s)
Biomedical Research/history , Collagen/metabolism , Endoplasmic Reticulum/physiology , History, 21st Century , Humans , JapanABSTRACT
Gihana investigates how cells coordinate their shape and polarity with chromosome segregation.
Subject(s)
Biomedical Research/history , Cell Biology/history , Chromosome Segregation , History, 21st Century , Humans , Interprofessional Relations , RwandaABSTRACT
Fritz-Laylin studies the evolution of complex protein networks associated with cell movement.
Subject(s)
Biological Evolution , Biomedical Research/history , Cell Biology/history , Cell Movement , Biomedical Research/economics , Career Choice , Cell Biology/education , History, 20th Century , History, 21st Century , Humans , MentorsABSTRACT
Silva investigates how ribosomal protein complexes are regulated by K63 ubiquitination.
Subject(s)
Proteostasis/genetics , Ribosomes/genetics , Ubiquitin/genetics , History, 21st Century , Humans , Lysine/metabolism , Neurons/cytology , Neurons/metabolism , Protein Biosynthesis , Proteolysis , Ribosomes/metabolism , Ubiquitin/history , Ubiquitin/metabolism , UbiquitinationABSTRACT
McLaughlin studies how neurons respond to acute and chronic stress.
Subject(s)
Neuroprotection , Neurosciences/history , Stress, Physiological , Women, Working/history , Female , History, 20th Century , History, 21st Century , Humans , Neurons , Portraits as TopicABSTRACT
Igaki explores how cell-cell communication directs tissue and tumor development.
Subject(s)
Caspase 1 , Drosophila Proteins , Membrane Proteins , Neurodegenerative Diseases , Animals , Caspase 1/genetics , Caspase 1/history , Caspase 1/metabolism , Drosophila Proteins/genetics , Drosophila Proteins/history , Drosophila Proteins/metabolism , Drosophila melanogaster , History, 20th Century , History, 21st Century , Humans , Membrane Proteins/genetics , Membrane Proteins/history , Membrane Proteins/metabolism , Neurodegenerative Diseases/genetics , Neurodegenerative Diseases/history , Neurodegenerative Diseases/metabolism , Neurodegenerative Diseases/pathology , Portraits as TopicABSTRACT
Chipuk studies the interaction between mitochondrial dynamics and cell death in cancer.
Subject(s)
Mitochondria , Humans , New YorkABSTRACT
Pearce investigates how metabolism is tailored to immune cell function.
Subject(s)
Immunity/genetics , Metabolism/genetics , HumansABSTRACT
Sanz-Moreno investigates how the cytoskeleton controls tumor biology.
Subject(s)
Biomedical Research , Neoplasms/metabolism , rho GTP-Binding Proteins/metabolism , History, 20th Century , History, 21st CenturyABSTRACT
Balla investigates how phosphoinositides control trafficking and signaling.
Subject(s)
Biomedical Research/history , Cell Biology/history , Phosphatidylinositols/history , Second Messenger Systems , Career Choice , History, 20th Century , History, 21st Century , Humans , Leadership , Mentors , Phosphatidylinositols/metabolismABSTRACT
Lackner investigates the tethering processes that position mitochondria.
Subject(s)
Escherichia coli/genetics , Escherichia coli/metabolism , Mitochondria/genetics , Mitochondria/metabolism , Biochemistry/history , History, 20th Century , History, 21st Century , Humans , Portraits as TopicABSTRACT
Song studies the trafficking and biological activities of cholesterol.