1.
Org Lett
; 24(19): 3445-3449, 2022 05 20.
Article
in English
| MEDLINE
| ID: mdl-35532542
ABSTRACT
Rhodium-catalyzed enantioselective addition of aryl and heteroaryl boron pinacol esters to pyridinium and quinolinium salts is developed for the synthesis of enantioenrichred dihydroheteroarenes. The methodology has enabled the synthesis of 2-heteroaryl-substituted dihydropyridines in high yield and ee, which provided efficient synthetic access to a nuphar alkaloid.