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Am J Obstet Gynecol ; 179(5): 1261-6, 1998 Nov.
Article in English | MEDLINE | ID: mdl-9822512

ABSTRACT

OBJECTIVE: Our purpose was to determine whether the continuation of antibiotics postoperatively after cesarean section in patients whose labors were complicated by chorioamnionitis would reduce the incidence of endometritis. STUDY DESIGN: Patients with a clinical diagnosis of chorioamnionitis treated with ampicillin during labor and who required cesarean delivery for obstetric indications received preoperative intravenous clindamycin and gentamicin and were randomized into 2 groups. Group 1 received no scheduled postoperative antibiotics and group 2 continued to receive clindamycin 900 mg every 8 hours and gentamicin 1.5 mg/kg every 8 hours until afebrile for a minimum of 24 hours (temperature

Subject(s)
Anti-Bacterial Agents/therapeutic use , Cesarean Section , Chorioamnionitis/drug therapy , Adult , Ampicillin/therapeutic use , Clindamycin/administration & dosage , Clindamycin/therapeutic use , Drug Administration Schedule , Endometritis/epidemiology , Female , Gentamicins/administration & dosage , Gentamicins/therapeutic use , Humans , Incidence , Infections/drug therapy , Injections, Intravenous , Penicillins/therapeutic use , Pregnancy , Preoperative Care , Puerperal Disorders/drug therapy
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