Comparación de las causas de ingreso y la morbilidad hospitalaria según la identidad de género de las personas atendidas en la Comunidad de Madrid / Causes of hospital admission and morbidity according to gender identity in the Autonomous Community of Madrid

El objetivo fue identificar las diferencias en causas de ingreso y morbilidad entre las personas transgénero (trans) y cisgénero (cis) mediante el registro de altas hospitalarias de la Comunidad de Madrid. Se describieron sus características, causas de ingreso y morbilidades, comparándolas mediante razón de prevalencias e intervalo de confianza al 95% (IC95%). Las 112 altas trans se diferenciaron de las 1.043.621 altas cis en que más frecuentemente se atendieron en un solo centro (55,4 vs 9,3%), eran menores de 49 años (75,9 vs 37,1%) y se financiaron de forma privada (2,7 vs 0,4%). Los ingresos por salud mental (23,96; IC95%: 17,41-32,78), y la morbilidad por VIH (11,26; IC95%: 5,46-20,93) fueron más frecuentes entre las altas trans. La información es limitada más allá de la modificación corporal, la salud mental y el VIH. Es necesario ampliar el conocimiento respecto a la salud de este colectivo

The objective was to identify differences in health between transgender (trans) and cisgender (cis) people using the hospital discharge survey from the Autonomous Community of Madrid. Their characteristics, causes of admission and morbidities were described, comparing them by prevalence ratio and confidence interval (95% CI). One hundred and twelve trans vs 1,043,621 cis discharges were studied. The main differences were that more frequently trans people had been attended in a single center (55.4 vs. 9.3%), were under 49 years old (75.9 vs. 37.1%) and had used private health services (2.7 vs. 0.4%). Admissions related to mental health problems (23.96; 95% CI: 17.41-32.78) and HIV morbidity (11.26 95% CI: 5.46-20.93) were more frequent among trans discharges. Information is limited beyond body modification, mental health, and HIV. It is necessary to improve the knowledge about trans population's health

[Causes of hospital admission and morbidity according to gender identity in the Autonomous Community of Madrid].

The objective was to identify differences in health between transgender (trans) and cisgender (cis) people using the hospital discharge survey from the Autonomous Community of Madrid. Their characteristics, causes of admission and morbidities were described, comparing them by prevalence ratio and confidence interval (95% CI). One hundred and twelve trans vs 1,043,621 cis discharges were studied. The main differences were that more frequently trans people had been attended in a single center (55.4 vs. 9.3%), were under 49 years old (75.9 vs. 37.1%) and had used private health services (2.7 vs. 0.4%). Admissions related to mental health problems (23.96; 95% CI: 17.41-32.78) and HIV morbidity (11.26 95% CI: 5.46-20.93) were more frequent among trans discharges. Information is limited beyond body modification, mental health, and HIV. It is necessary to improve the knowledge about trans population's health.

Encefalopatía por hiperamoniemia en el adolescente / Encephalopathy by hyperammonemia in the teenager

Fundamento. La hiperamoniemia origina múltiples alteraciones,principalmente en el sistema nervioso central.Si el fallo hepático no es su causa, deberán investigarseotras etiologías menos frecuentes intentandollegar a un diagnóstico definitivo.Caso clínico. Presentamos el caso de un paciente de16 años que ingresó por encefalopatía aguda e hiperamoniemia.Tras realización de analítica, TAC cerebral,ecografía y Doppler abdominal, se inició tratamientoempírico de hiperamoniemia secundaria a un errorinnato del ciclo de la urea. Se trató el edema cerebraly se tomaron medidas para eliminación del amoniacosin resultado favorable, falleciendo a los cuatro días delingreso.Conclusiones. El complejo manejo de la hiperamoniemiay la alta morbi-mortalidad que conlleva requiere unmanejo multidisciplinar. La instauración de tratamientoprecoz e identificación de la causa son claves para mejorarlos resultados(AU)

Background. Hyperammonemia causes several alterations,mainly in the central nervous system. If hepaticfailure is not its etiology, other less frequent causesmust be investigated in the search for a definitive diagnosis.Clinical case. We report the case of a 16 year old patientadmitted for acute encephalopathy and hyperammonemia.After analysis, brain CT, ultrasound and abdominalDoppler, we began empirical treatment of hyperammoniemiasecondary to disorders of the urea cycle. Wetreated the brain edema and eliminated ammonia butwe did not obtain favourable results and the patientdied four days later.Conclusions. The complex management of hyperammonemiaand the high morbidity and mortality involvedrequire a multidisciplinary approach. Only earlytreatment and identification of the hyperammonemia`setiology can avoid high morbidity and mortality in thesepatients(AU)

[Encephalopathy by hyperammonemia in teenagers]. / Encefalopatía por hiperamoniemia en el adolescente.

BACKGROUND: Hyperammonemia causes several alterations, mainly in the central nervous system. If hepatic failure is not its etiology, other less frequent causes must be investigated in the search for a definitive diagnosis. CLINICAL CASE: We report the case of a 16 year old patient admitted for acute encephalopathy and hyperammonemia. After analysis, brain CT, ultrasound and abdominal Doppler, we began empirical treatment of hyperammonemia secondary to disorders of the urea cycle. We treated the brain edema and eliminated ammonia but we did not obtain favourable results and the patient died four days later. CONCLUSIONS: The complex management of hyperammonemia and the high morbidity and mortality involved require a multidisciplinary approach. Only early treatment and identification of the hyperammonemia's etiology can avoid high morbidity and mortality in these patients.

Rabdomiolisis de origen multifactorial en paciente con intoxicación acuosa / Rhabdomyolysis due to multifactorial causes in water intoxication patient

La rabdomiolisis es un síndrome caracterizado por necrosis muscular y liberación del contenido de las células musculares al torrente sanguíneo que presenta etiologías muy diversas, algunas sólo parcialmente explicadas. En la práctica clínica es preciso iniciar un rápido diagnóstico en aras de prevenir complicaciones tan severas como el fallo renal agudo. A continuación presentamos un caso de rabdomiolisis relacionada con el tratamiento con olanzapina (AU)

Rhabdomyolysis is a syndrome caused by injury to skeletal muscle and involves leakage of the intracellular contents into plasma. Rhabdomyolysis has many causes, some of them are more easily understood than others. The physician must be alert to the diagnosis of rhabdomyolysis and to its subtle presentation to prevent the most severe complication of acute renal failure. We report one case of rhabdomyolysis induced by treatment with olanzapine (AU)

Exoftalmos y ptosis palpebral en paciente inmunodeprimido / Exoftalmos and palpebral ptosis in non immunocompetent patient

La mucormicosis es una micosis oportunista que posee una alta tasa de mortalidad global, con mal pronóstico. En el presente caso clínico se muestra un paciente ingresado en UCI por insuficiencia respiratoria secundaria a neumonía; entre sus antecedentes figura carcinoma de laringe en remisión completa tras tratamiento con quimio y radioterapia. Desarrolla una lesión infrapalpebral que se extiende rápidamente de forma bilateral adquiriendo aspecto necrótico que inicialmente no poseía. Con dicha evolución se realiza tratamiento con anfotericina B liposomal y estimulantes de colonias previa biopsia de lesión, cuyo cultivo posterior muestra crecimiento de Mucor. Este tipo de patologías deben sospecharse inicialmente en todo paciente con antecedentes de neoplasia, su tratamiento debe ser agresivo y precoz. En el momento que se sospecha el diagnóstico existe una gran destrucción tisular, motivo por el que los pacientes suelen fallecer pese instauración de terapias agresivas (AU)