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Am J Cardiol ; 96(3): 464-6, 2005 Aug 01.
Article in English | MEDLINE | ID: mdl-16054484

ABSTRACT

Three brothers with arthrogryposis multiplex congenita survived into adulthood. In their fourth decade, the clinical course for each brother became complicated by severe stenoses of their aortic and mitral valves. One brother died suddenly, and the remaining 2 developed heart failure. requiring valvular replacement.


Subject(s)
Aortic Valve Stenosis/genetics , Arthrogryposis/genetics , Mitral Valve Stenosis/genetics , Adult , Aortic Valve Stenosis/surgery , Fatal Outcome , Heart Valve Prosthesis Implantation , Humans , Male , Mitral Valve Stenosis/surgery
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