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1.
PRiMER ; 3: 26, 2019.
Article in English | MEDLINE | ID: mdl-32537597

ABSTRACT

INTRODUCTION: Medical schools have an enduring need to provide ongoing faculty development and to foster educational alliances between teachers and learners, so that feedback provided to learners is both frequent and of high quality. We hypothesized that medical students trained as academic detailers with a mission to increase the emphasis on feedback could serve in this role during our clerkship, while still being evaluated as students in our clerkship rotation. METHODS: The family medicine clerkship at Mayo Clinic School of Medicine launched a revised curriculum in 2016 in which students were taught how they might build an educational alliance with preceptors, were taught characteristics of high-quality feedback, and practiced requesting more useful feedback when initial quality was poor. After utilizing a clerkship-specific curriculum with small group sessions on receiving feedback, and training students and preceptors on the SNAPPs model, students were then directed to request feedback from their preceptors and model successful feedback conversations for preceptors. The study evaluated the medical students' summative evaluations to compare the rate from the preintervention year (2015-2016) and the intervention year (2016-2017) at which preceptors added comments on students' use of feedback. RESULTS: Preceptors' written comments about students seeking feedback increased at about a four-fold rate (74.4% vs 18.8%, P<.001) after implementing a suite of changes to our clerkship curriculum. CONCLUSIONS: Using medical students to change preceptor behaviors was an important part of our suite of interventions. This intervention directed preceptor attention toward our instructional goal of increased medical student feedback.

2.
J Hum Lact ; 34(2): 331-336, 2018 May.
Article in English | MEDLINE | ID: mdl-29596761

ABSTRACT

BACKGROUND: The American Academy of Pediatrics and the National Academy of Medicine recommend vitamin D supplementation for breastfeeding infants. However, compliance with this recommendation is poor. Maternal supplementation with vitamin D is a safe and effective alternative to achieving vitamin D sufficiency in breastfeeding infants, and mothers have indicated a preference for self-supplementation over infant supplementation. Research aim: We sought to explore Family Medicine clinicians' knowledge, attitudes, and practices regarding vitamin D supplementation recommendations for breastfeeding dyads. METHODS: Fifty-six Family Medicine clinicians (including faculty physicians, resident physicians, and nurse practitioners/physician assistants) completed an online, anonymous survey regarding their knowledge and practices concerning vitamin D supplementation for breastfeeding infants. RESULTS: The vast majority of clinicians (92.9%) correctly identified the American Academy of Pediatrics' 2008 recommended dose for vitamin D supplementation in breastfeeding infants and estimated recommending vitamin D supplementation of exclusively breastfeeding infants 70.1% of the time. If all options were equivalent, clinicians would prefer to offer maternal or infant supplementation (50%) or maternal supplementation (37.5%) over infant supplementation (12.5%). Most (69.6%) preferred daily over monthly supplementation regimens. CONCLUSION: Family Medicine clinicians are knowledgeable regarding current recommendations for vitamin D supplementation in breastfeeding infants. They are also open to recommending maternal supplementation or offering parents a choice of maternal or infant vitamin supplementation.


Subject(s)
Breast Feeding , Clinical Competence/standards , Health Knowledge, Attitudes, Practice , Health Personnel/standards , Vitamin D Deficiency/complications , Adult , Aged , Chi-Square Distribution , Clinical Competence/statistics & numerical data , Cross-Sectional Studies , Dietary Supplements , Family Practice/methods , Family Practice/organization & administration , Female , Health Personnel/psychology , Humans , Infant , Infant, Newborn , Middle Aged , Milk, Human/chemistry , Milk, Human/metabolism , Surveys and Questionnaires , Vitamin D Deficiency/metabolism
3.
Bone ; 110: 321-325, 2018 05.
Article in English | MEDLINE | ID: mdl-29486367

ABSTRACT

OBJECTIVE: Supplementing lactating mothers with high doses of vitamin D3 can adequately meet vitamin D requirements of the breastfed infant. We compared the effect of bolus versus daily vitamin D3 dosing in lactating mothers on vitamin D3 catabolism. We hypothesized that catabolism of 25(OH)D3 to 24,25(OH)2D3 would be greater in the bolus than in the daily dose group. DESIGN, SETTING AND PATIENTS: Randomized controlled trial (clinicaltrials.govNCT01240265) in 40 lactating women. INTERVENTIONS: Subjects were randomized to receive vitamin D3 orally, either a single dose of 150,000IU or 5000IU daily for 28days. Vitamin D metabolites were measured in serum and breast milk at baseline, 1, 3, 7, 14 and 28days. MAIN OUTCOME MEASURE: Temporal changes in the serum 24,25(OH)2D3/25(OH)D3 ratio. RESULTS: The concentration of serum 24,25(OH)2D3 was directly related to that of 25(OH)D in both groups (r2=0.63; p<0.001). The mean (±SD) 24,25(OH)2D3/25(OH)D3 ratio remained lower at all time points than baseline values in the daily dose group (0.093±0.024, 0.084±0.025, 0.083±0.024, 0.080±0.020, 0.081±0.023, 0.083±0.018 at baseline, 1, 3, 7, 14, and 28days, respectively). In the single dose group, the increase in 24,25(OH)2D3 lagged behind that of 25(OH)D, but the 24,25(OH)2D3/25(OH)D3 values (0.098±0.032, 0.067±0.019, 0.081±0.017, 0.092±0.024, 0.103±0.020, 0.106±0.024, respectively) exceeded baseline values at 14 and 28days and were greater than the daily dose group at 14 and 28days (p=0.003). The 24,25(OH)2D3/25(OH)D3 ratio remained in the normal range with both dosing regimens. Greater breast milk vitamin D3 values in the single dose group were inversely associated with the 24,25(OH)2D3/25(OH)D3 ratio (r2=0.14, p<0.001), but not with daily dosing. CONCLUSIONS: After a 14-day lag, a single high dose of vitamin D led to greater production of 24,25(OH)2D3, presumably via induction of the 24-hydroxylase enzyme (CYP24A1), relative to the 25(OH)D3 value than did daily vitamin D supplementation, and this effect persisted for at least 28days after vitamin D administration. A daily dose of vitamin D may have more lasting effectiveness in increasing 25(OH)D3 with lesser diversion of 25(OH)D3 to 24,25(OH)2D3 than does larger bolus dosing.


Subject(s)
24,25-Dihydroxyvitamin D 3/blood , Calcifediol/blood , Vitamin D/administration & dosage , Adult , Chromatography, Liquid , Dietary Supplements , Female , Humans , Infant , Lactation/drug effects , Tandem Mass Spectrometry , Young Adult
4.
Ann Fam Med ; 15(1): 68-70, 2017 01.
Article in English | MEDLINE | ID: mdl-28376463

ABSTRACT

Daily vitamin D supplementation is recommended for breastfed infants, but alternative methods include enriching breast milk with vitamin D through maternal supplementation or intermittent high-dose vitamin D. We determined maternal preferences for vitamin D supplementation in 140 mothers with exclusively breastfed infants, and 44 who used both breast and formula milk. Only 101 (55%) supplemented their infants with vitamin D. One hundred sixty (88%) preferred supplementing themselves rather than their infants, and 102 (57%) preferred daily to monthly supplementation. Safety was most important in choosing a method of supplementation. Taking maternal preferences into consideration may improve adequate intakes of vitamin D in breastfed infants.


Subject(s)
Breast Feeding , Dietary Supplements , Patient Preference/statistics & numerical data , Vitamin D/administration & dosage , Adult , Female , Humans , Infant , Infant, Newborn , Milk, Human , Mothers , Surveys and Questionnaires , United States , Young Adult
5.
Psychosomatics ; 56(4): 354-61, 2015.
Article in English | MEDLINE | ID: mdl-26096322

ABSTRACT

BACKGROUND: Complex interrelationships appear to exist among depression, diabetes, and obesity, and it has been proposed that both diabetes and obesity have an association with depression. OBJECTIVE: The purpose of our study was to explore the effect of obesity and diabetes on response to the treatment of depression. Our hypothesis was that obesity and the diagnosis of diabetes in primary care patients with depression would have no effects on depression remission rates 6 months after diagnosis. METHODS: A retrospective chart review analysis of 1894 adult (age ≥18y) primary care patients diagnosed with major depressive disorder or dysthymia and a Patient Health Questionnaire-9 score ≥10 from January 1, 2008, through September 30, 2012. Multiple logistic regression modeling retaining all independent variables was performed for the outcome of remission (Patient Health Questionnaire-9 < 5) 6 months after diagnosis. RESULTS: The presence of obesity (odds ratio = 0.937, 95% CI: 0.770-1.140, p = 0.514) or the diagnosis of diabetes (odds ratio = 0.740, 95% CI: 0.535-1.022, p = 0.068) did not affect the likelihood of remission, while controlling for the other independent variables. CONCLUSIONS: In primary care patients treated for depression, the presence of diabetes or obesity at the time of diagnosis of depression does not appear to significantly affect remission of depressive symptoms 6 months after diagnosis.


Subject(s)
Depressive Disorder/epidemiology , Depressive Disorder/therapy , Diabetes Mellitus/epidemiology , Obesity/epidemiology , Primary Health Care , Adolescent , Adult , Aged , Aged, 80 and over , Comorbidity , Depressive Disorder/psychology , Diabetes Mellitus/psychology , Female , Humans , Male , Middle Aged , Obesity/psychology , Remission Induction , Retrospective Studies , Risk Factors , Young Adult
6.
Mayo Clin Proc ; 90(5): 577-86, 2015 May.
Article in English | MEDLINE | ID: mdl-25939935

ABSTRACT

OBJECTIVE: To determine the incidence trend of 25-hydroxyvitamin D (25(OH)D) values above 50 ng/mL and associated toxicity. PATIENTS AND METHODS: We conducted a retrospective population-based study in Olmsted County, Minnesota, in the 10-year period from January 1, 2002, through December 31, 2011, by using the Rochester Epidemiology Project. Individuals were eligible if they resided in Olmsted County during the study period and had a measured 25(OH)D value above 50 ng/mL. The date of the first 25(OH)D value above 50 ng/mL was considered the index date for incidence determination. Hypercalcemia, the primary vitamin D toxicity, was considered potentially associated with the 25(OH)D concentration if it was measured within 3 months of the 25(OH)D measurement, and such cases had a medical record review. RESULTS: Of 20,308 total 25(OH)D measurements, 1714 (8.4%), 123 (0.6%), and 37 (0.2%) unique persons had 25(OH)D values above 50, 80 and above, and 100 ng/mL and above, respectively. The age- and sex-adjusted incidence of 25(OH)D values above 50 ng/mL increased from 9 to 233 cases per 100,000 person-years from 2002 to 2011 (P<.001), respectively, and was greatest in persons aged 65 years and older (P<.001) and in women (P<.001). Serum 25(OH)D values were not significantly related to serum calcium values (P=.20) or with the risk of hypercalcemia (P=.24). A medical record review identified 4 cases (0.2%) in whom 25(OH)D values above 50 ng/mL were temporally associated with hypercalcemia, but only 1 case had clinical toxicity associated with the highest observed 25(OH)D value of 364 ng/mL. CONCLUSION: The incidence of 25(OH)D values above 50 ng/mL increased significantly between 2002 and 2011 without a corresponding increase in acute clinical toxicity.


Subject(s)
Hypercalcemia/blood , Hypercalcemia/epidemiology , Vitamin D/analogs & derivatives , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Incidence , Infant , Male , Middle Aged , Retrospective Studies , Time Factors , Vitamin D/blood , Young Adult
7.
Popul Health Manag ; 17(3): 180-4, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24495212

ABSTRACT

Depression symptoms contribute to significant morbidity and health care utilization. The aim of this study was to determine the impact of symptom improvement (to remission) on outpatient clinical visits by depressed primary care patients. This study was a retrospective chart review analysis of 1733 primary care patients enrolled into collaborative care management (CCM) or usual care (UC) with 6-month follow-up data. Baseline data (including demographic information, clinical diagnosis, and depression severity) and 6-month follow-up data (Patient Health Questionnaire scores and the number of outpatient visits utilized) were included in the data set. To control for individual patient complexity and pattern of usage, the number of outpatient visits for 6 months prior to enrollment also was measured as was the presence of medical comorbidities. Multiple logistic regression analysis demonstrated that clinical remission at 6 months was an independent predictor of outpatient visit outlier status (>8 visits) (odds ratio [OR] 0.609, confidence interval (CI) 0.460-0.805, P<0.01) when controlling for all other independent variables including enrollment into CCM or UC. The OR of those patients not in remission at 6 months having outpatient visit outlier status was the inverse of this at 1.643 (CI 1.243-2.173). The most predictive variable for determining increased outpatient visit counts after diagnosis of depression was increased outpatient visits prior to diagnosis (OR 4.892, CI 3.655-6.548, P<0.01). In primary care patients treated for depression, successful treatment to remission at 6 months decreased the likelihood of the patient having more than 8 visits during the 6 months after diagnosis.


Subject(s)
Ambulatory Care , Cooperative Behavior , Depression/therapy , Outcome Assessment, Health Care , Primary Health Care , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Medical Audit , Middle Aged , Odds Ratio , Retrospective Studies , Surveys and Questionnaires , Young Adult
8.
J Prim Care Community Health ; 5(1): 30-5, 2014 Jan 01.
Article in English | MEDLINE | ID: mdl-24327598

ABSTRACT

BACKGROUND: The inclusion of mental health issues in the evaluation of multimorbidity generally has been as the presence or absence of the condition rather than severity, complexity, or stage. The hypothesis for this study was that clinical outcome of the depression 6 months after enrollment into collaborative care management would have a role in predicting future complexity of care tier. METHODS: This study was a retrospective chart review of 1894 primary care patients who were diagnosed with major depressive disorder or dysthymia as of December 2012. Multiple logistic regression analysis was used to test the independent associations between each variable and the odds of being included in the higher tiers (HT) group. RESULTS: Age (odds ratio [OR] = 1.022, confidence interval [CI] = 1.013-1.030, P < .001), female gender (OR = 1.380, CI = 1.020-1.868, P = .037), being married (OR = 0.730, CI = 0.563-0.947, P = .018), and the presence of comorbidities (1, OR = 1.986, CI = 1.485-2.656, P < .001; ≥ 2, OR = 4.678, CI = 3.242-6.750, P < .001) were independently associated with future HT levels. The presence of persistent depressive symptoms (PHQ-9 ≥ 10) at 6 months conferred 2.280 (CI = 1.673-3.107, P < .001) times likely odds of HT level compared with clinical remission at 6 months. CONCLUSION: Patients with the diagnosis of major depression or dysthymia had greater odds of complex tier levels in the future, if depression was not treated to remission by 6 months. This study demonstrated the importance of the goal of significant improvement (ie, remission) of depression symptoms by 6 months (especially those older patients with more comorbidity) from entering into the higher complexity tiers.


Subject(s)
Case Management , Delivery of Health Care, Integrated , Depressive Disorder, Major/therapy , Dysthymic Disorder/therapy , Primary Health Care/methods , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Comorbidity , Female , Humans , Logistic Models , Male , Marital Status , Middle Aged , Retrospective Studies , Sex Factors , Young Adult
9.
Mayo Clin Proc ; 88(12): 1378-87, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24290111

ABSTRACT

OBJECTIVE: To determine whether a single monthly supplement is as effective as a daily maternal supplement in increasing breast milk vitamin D to achieve vitamin D sufficiency in their infants. PATIENTS AND METHODS: Forty mothers with exclusively breast-fed infants were randomized to receive oral cholecalciferol (vitamin D3) 5000 IU/d for 28 days or 150,000 IU once. Maternal serum, breast milk, and urine were collected on days 0, 1, 3, 7, 14, and 28; infant serum was obtained on days 0 and 28. Enrollment occurred between January 7, 2011, and July 29, 2011. RESULTS: In mothers given daily cholecalciferol, concentrations of serum and breast milk cholecalciferol attained steady levels of 18 and 8 ng/mL, respectively, from day 3 through 28. In mothers given the single dose, serum and breast milk cholecalciferol peaked at 160 and 40 ng/mL, respectively, at day 1 before rapidly declining. Maternal milk and serum cholecalciferol concentrations were related (r=0.87). Infant mean serum 25-hydroxyvitamin D concentration increased from 17±13 to 39±6 ng/mL in the single-dose group and from 16±12 to 39±12 ng/mL in the daily-dose group (P=.88). All infants achieved serum 25-hydroxyvitamin D concentrations of more than 20 ng/mL. CONCLUSION: Either single-dose or daily-dose cholecalciferol supplementation of mothers provided breast milk concentrations that result in vitamin D sufficiency in breast-fed infants. CLINICAL TRIAL REGISTRATION: clinicaltrials.gov NCT01240265.


Subject(s)
Breast Feeding , Cholecalciferol/administration & dosage , Cholecalciferol/metabolism , Dietary Supplements , Milk, Human/metabolism , Mothers , Vitamin D Deficiency/drug therapy , Vitamins/administration & dosage , Vitamins/metabolism , Adult , Cholecalciferol/blood , Cholecalciferol/urine , Dose-Response Relationship, Drug , Drug Administration Schedule , Female , Humans , Infant , Infant, Newborn , Lactation , Male , Time Factors , Treatment Outcome , Vitamin D Deficiency/prevention & control , Vitamins/blood , Vitamins/urine
10.
Qual Manag Health Care ; 22(2): 161-6, 2013.
Article in English | MEDLINE | ID: mdl-23542371

ABSTRACT

PURPOSE: To assess delays in response to patient secure e-mail messages in primary care. BACKGROUND: Secure electronic messages are initiated by primary care patients. Timely response is necessary for patient safety and quality. DATA SOURCE: A database of secure messages. SAMPLE: A random sample of 353 secure electronic messages initiated by primary care patients treated in 4 clinics. OUTCOME MEASURES: Message not opened after 12 hours or messages not responded to after 36 hours. RESULTS: A total of 8.5% of electronic messages were not opened within 12 hours, and 17.6% did not receive a response in 36 hours. Clinic location, being a clinic employee, and patient sex were not related to delays. Patients older than 50 years were more likely to receive a delayed response (25.7% delayed, P = .013). The risk of both kinds of delays was higher on weekends (P < .001 for both). CONCLUSION: The e-mail message system resulted in high rates of delayed response. Delays were concentrated on weekends (Friday-Sunday). Reducing delayed responses may require automatic rerouting of messages to message centers staffed 24-7 or other mechanisms to manage this after-hours work flow.


Subject(s)
Electronic Mail/standards , Primary Health Care/standards , Adolescent , Adult , Aged , Aged, 80 and over , Electronic Mail/organization & administration , Female , Humans , Male , Middle Aged , Primary Health Care/methods , Primary Health Care/organization & administration , Quality of Health Care/organization & administration , Quality of Health Care/statistics & numerical data , Retrospective Studies , Time Factors , Young Adult
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