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1.
World J Clin Oncol ; 13(6): 485-495, 2022 Jun 24.
Article in English | MEDLINE | ID: mdl-35949432

ABSTRACT

The management of patients with advanced non-small cell lung carcinoma (NSCLC) has undergone major changes in recent years. On the one hand, improved sensitivity of diagnostic tests, both radiological and endoscopic, has altered the way patients are staged. On the other hand, the arrival of new drugs with antitumoral activity, such as targeted therapies or immunotherapy, has changed the prognosis of patients, improving disease control and prolonging survival. Finally, the development of radiotherapy and surgical and interventional radiology techniques means that radical ablative treatments can be performed on metastases in any location in the body. All of these advances have impacted the treatment of patients with advanced lung cancer, especially in a subgroup of these patients in which all of these treatment modalities converge. This poses a challenge for physicians who must decide upon the best treatment strategy for each patient, without solid evidence for one optimal mode of treatment in this patient population. The aim of this article is to review, from a practical and multidisciplinary perspective, published evidence on the management of oligometastatic NSCLC patients. We evaluate the different alternatives for radical ablative treatments, the role of primary tumor resection or radiation, the impact of systemic treatments, and the therapeutic sequence. In short, the present document aims to provide clinicians with a practical guide for the treatment of oligometastatic patients in routine clinical practice.

7.
JACC Case Rep ; 3(10): 1339-1342, 2021 Aug 18.
Article in English | MEDLINE | ID: mdl-34471891
8.
Cir. Esp. (Ed. impr.) ; 98(10): 574-581, dic. 2020. tab
Article in Spanish | IBECS | ID: ibc-194163

ABSTRACT

La expansión de la pandemia producida por el nuevo coronavirus SARS-CoV-2 ha obligado a focalizar casi toda la asistencia sanitaria en pacientes con enfermedad COVID-19, obligando a suspender la mayoría de intervenciones quirúrgicas electivas programadas. La cirugía torácica es eminentemente oncológica, por lo que resulta obligada una adecuada priorización de los pacientes para ser intervenidos lo antes posible y en condiciones de máxima seguridad. Por otra parte, la afectación pulmonar grave COVID-19 presenta complicaciones que con frecuencia requieren procedimientos quirúrgicos torácicos urgentes en un contexto nuevo. La Sociedad Española de Cirugía Torácica (SECT) ha desarrollado este documento para establecer unas recomendaciones básicas para mantener la actividad quirúrgica electiva imprescindible y para orientar a los cirujanos que deban afrontar urgencias torácicas en este nuevo y desconocido entorno


Expansion of the pandemic produced by new coronavirus SATS-CoV-2 has made healthcare focused on patients with COVID-19 disease, leading to discontinue most of elective surgical procedures. Being thoracic surgery eminently oncological, an optimal triage of patients amenable to be safely operated on is mandatory. Moreover, severe pulmonary involvement by COVID-19 causes complications frequently needing urgent thoracic surgical procedures under a new context. The Spanish Society of Thoracic Surgery (SECT) has developed this document to establish basic recommendations to keep up essential elective surgical activity and to guide surgeons facing thoracic urgencies in this new and unknown environment


Subject(s)
Humans , Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Pandemics , Elective Surgical Procedures/standards , Thoracic Surgery/standards , Societies, Medical , Spain/epidemiology
9.
Cir Esp (Engl Ed) ; 98(10): 574-581, 2020 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-33040975

ABSTRACT

Expansion of the pandemic produced by new coronavirus SATS-CoV-2 has made healthcare focused on patients with COVID-19 disease, leading to discontinue most of elective surgical procedures. Being thoracic surgery eminently oncological, an optimal triage of patients amenable to be safely operated on is mandatory. Moreover, severe pulmonary involvement by COVID-19 causes complications frequently needing urgent thoracic surgical procedures under a new context. The Spanish Society of Thoracic Surgery (SECT) has developed this document to establish basic recommendations to keep up essential elective surgical activity and to guide surgeons facing thoracic urgencies in this new and unknown environment.


Subject(s)
COVID-19/prevention & control , COVID-19/transmission , Elective Surgical Procedures , Emergencies , Risk Management , Thoracic Surgical Procedures , COVID-19/epidemiology , Chest Tubes , Hospital Units , Humans , Infection Control , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Lung Transplantation , Pandemics , Risk Assessment , SARS-CoV-2 , Spain , Tracheostomy , Triage
10.
Innovations (Phila) ; 14(1): 5-16, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30848708

ABSTRACT

Robotic totally endoscopic coronary artery bypass grafting (TECAB) was introduced in 1998 and has over a period of two decades gradually emerged from single-vessel revascularization to multivessel bypass grafting. Dedicated centers have continuously evolved and further developed this minimally invasive method of coronary bypass surgery. A literature review was conducted to assess intra- and postoperative outcomes of TECAB. PubMed returned 19 comprehensive articles on TECAB. Investigation was focused on perioperative outcome parameters, i.e.: operative time, conversion to larger incision, revision for bleeding, atrial fibrillation, stroke, acute renal failure, and mortality. Outcome from the analysis of 2,397 reported cases showed an average operative time of 291 ± 57 minutes (range 112 to 1,050), conversion rate to larger incisions at 11.5%, and perioperative mortality at 0.8%. Pooled data demonstrated 4.2% operative revision rate due to postoperative hemorrhage, 1.0% stroke incidence, 1.6% acute renal failure, and 13.3% de novo atrial fibrillation. The mean length of hospital stay measured 5.8 ± 1.7 days. Conversion rates and operative times decreased over time. According to data in the literature, coronary bypass surgery carried out in completely endoscopic fashion utilizing robotic assistance can require relatively extensive operative times and conversion rates are somewhat higher than in other robotic cardiac surgery. However, major postoperative events lie in an acceptable range. TECAB remains the surgical revascularization method with the least tissue trauma and represents an opportunity for coronary artery bypass grafting via port access. Rates of major complications are at least similar to conventional surgical access procedures.


Subject(s)
Coronary Artery Bypass/methods , Coronary Artery Disease/surgery , Endoscopy/methods , Robotic Surgical Procedures/methods , Acute Kidney Injury/complications , Aged , Aged, 80 and over , Atrial Fibrillation/complications , Female , Humans , Length of Stay , Male , Middle Aged , Operative Time , Perioperative Period/mortality , Postoperative Complications/epidemiology , Postoperative Hemorrhage/complications , Stroke/complications , Treatment Outcome
11.
Asian Cardiovasc Thorac Ann ; 27(2): 93-97, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30525867

ABSTRACT

BACKGROUND: Pulmonary resection is, by far, the primary cause of bronchial fistula. This is a severe complication because of its morbidity and mortality and the related consumption of resources. Definitive closure continues to be a challenge with several therapeutic options, but none are optimal. We describe our experience in bronchoscopic application of ethanolamine and lauromacrogol 400 for the treatment of post-resection bronchial fistulas. METHODS: Clinical records of 8 patients treated using this technique were collected prospectively. The diagnosis of a fistula was confirmed by flexible bronchoscopy. Sclerosis was indicated in the context of multimodal treatment. Sclerosant injection was performed under general anesthesia with a Wang 22G needle through a flexible bronchoscope. The procedure was repeated at 2-week intervals until definitive closure of the fistula was confirmed. RESULTS: Fistula closure was achieved in 7 (87.5%) of the 8 patients, with persistence of the fistula in one patient who could not complete the treatment because of recurrence of his neoplastic pathology. No recurrence or complications related to the technique were registered. CONCLUSIONS: Bronchoscopic sclerosis by means of submucosal injection of lauromacrogol 400 or ethanolamine should be part of the multimodal treatment of bronchopleural fistula after lung resection, pending further studies that contribute to the accurate establishment of optimal indications for this procedure.


Subject(s)
Bronchial Fistula/therapy , Bronchoscopy , Ethanolamine/administration & dosage , Pneumonectomy/adverse effects , Polidocanol/administration & dosage , Sclerosing Solutions/administration & dosage , Sclerotherapy/methods , Aged , Bronchial Fistula/diagnostic imaging , Bronchial Fistula/etiology , Bronchoscopy/adverse effects , Ethanolamine/adverse effects , Humans , Male , Middle Aged , Polidocanol/adverse effects , Prospective Studies , Sclerosing Solutions/adverse effects , Sclerotherapy/adverse effects , Time Factors , Treatment Outcome
15.
Interact Cardiovasc Thorac Surg ; 26(5): 869-872, 2018 05 01.
Article in English | MEDLINE | ID: mdl-29325041

ABSTRACT

Catheter ablation for symptomatic and drug-resistant atrial fibrillation is considered as the main acquired cause of pulmonary vein stenosis in adults. Controversy currently exists about the optimal treatment approach of this entity. Stenting seems to achieve lower vessel restenosis rates than isolated balloon angioplasty. However, these techniques are not exempt from complications. We present a case of spontaneous massive haemothorax presenting as a late complication of stent implantation in a patient with pulmonary vein stenosis.


Subject(s)
Atrial Fibrillation/surgery , Catheter Ablation/adverse effects , Hemothorax/etiology , Postoperative Complications/etiology , Stenosis, Pulmonary Vein/surgery , Stents/adverse effects , Hemothorax/diagnosis , Hemothorax/surgery , Humans , Male , Middle Aged , Postoperative Complications/diagnosis
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