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Sud Med Ekspert ; 49(1): 20-4, 2006.
Article in Russian | MEDLINE | ID: mdl-16509206

ABSTRACT

It was found possible to use fluorescence-polarization immunoassay (FPIA) in screening of opium drugs in blood and blood serum as a preliminary test. The results of the study of blood and serum samples by FPIA and chromato-mass-spectroscopy were compared. As a criterion of assessment of the preliminary study results we propose to use a cutoff point by serial production of the analysed blood samples of the threshold morphine concentrations (20 ng/ml for living subjects and 40 ng/ml--for corpses). The method of opiates screening in blood proposed is characterized by fast conduction, high specificity and precision, small amounts of the expert material.


Subject(s)
Fluorescence Polarization Immunoassay , Forensic Medicine/methods , Morphine/blood , Cadaver , Humans , Sensitivity and Specificity
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