Search | VHL Regional Portal

1.

A subchronic inhalation study with unleaded petrol in rats.

Vyskocil, A; Tusl, M; Obrsál, J; Zaydlar, K.

J Appl Toxicol ; 8(4): 239-42, 1988 Aug.

Article in English | MEDLINE | ID: mdl-3183289

ABSTRACT

The effect of intermittent 2 months' exposure to 2 g/m3 unleaded petrol on the hypothalamo-pituitary-thyroid-adrenal system was evaluated by measuring hypothalamic noradrenaline (NA), serum corticosterone (CS), thyroxine (T4) and adrenal catecholamine (CA) levels in male rats. Serum CS and adrenal CA were increased and hypothalamic NA was decreased by exposure. No changes were observed in serum T4. Exposure induced an increase in spleen, kidney, liver and lung weights; weights of adrenals and hypothalamus were not changed. All the petrol-induced effects depended on the length of exposure. Rats exposed to petrol gained less weight than controls. The results suggest a non-specific stress response in the rat.

Subject(s)

Gasoline/toxicity , Petroleum/toxicity , Administration, Inhalation , Adrenal Glands/analysis , Animals , Catecholamines/analysis , Corticosterone/blood , Hypothalamus/analysis , Hypothalamus/drug effects , Lead , Male , Norepinephrine/analysis , Organ Size/drug effects , Rats , Rats, Inbred Strains , Thyroxine/blood

2.

The effect of low CO concentrations on the organism.

Tusl, M; Vyskocil, A; Obrsál, J.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 30(4-5): 489-541, 1987.

Article in English | MEDLINE | ID: mdl-3329763

Subject(s)

Carbon Monoxide/pharmacology , Adrenal Glands/drug effects , Animals , Carbon Monoxide Poisoning/metabolism , Catecholamines/metabolism , Corticosterone/blood , Histamine/metabolism , Humans , Liver/drug effects , Lung/drug effects , Rats , Rats, Inbred Strains , Spleen/drug effects , Thyroid Hormones/metabolism

3.

[The effect of caffeine on performance in rats with radiation sickness]. / Ovlivnení výkonu u krys podáním kofeinu v prubehu nemoci z ozárení.

Tusl, M; Obrsál, J; Svorcová, S.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 28(1): 97-111, 1985.

Article in Czech | MEDLINE | ID: mdl-3879901

Subject(s)

Caffeine/pharmacology , Physical Exertion/drug effects , Radiation Injuries, Experimental/physiopathology , Animals , Male , Rats

4.

[Determination of carbon tetrachloride and its metabolites in the blood and liver of rats using gas chromatography]. / Stanovení tetrachlormetanu a jeho metabolitu v krvi a játrech potkanu uzitím plynové chromatografie.

Obrsál, J; Smejkalová, J.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 28(3-4): 341-7, 1985.

Article in Czech | MEDLINE | ID: mdl-3879919

Subject(s)

Carbon Tetrachloride/analysis , Chloroform/analysis , Chromatography, Gas/methods , Liver/analysis , Animals , Carbon Tetrachloride/blood , Chloroform/blood , Rats

5.

[Changes in the level of CCl4 and its toxic radical .CCl3 in the blood and liver in rats of both sexes]. / Zmeny koncentrace CCl4 a jeho toxického radikálu .CCl3 v krvi a játrech potkanu obou pohlaví.

Smejkalová, J; Obrsál, J; Tusl, M; Simek, J.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 28(3-4): 391-8, 1985.

Article in Czech | MEDLINE | ID: mdl-3879924

Subject(s)

Carbon Tetrachloride/metabolism , Chloroform/metabolism , Liver/metabolism , Animals , Carbon Tetrachloride/blood , Chloroform/blood , Female , Kinetics , Male , Rats , Rats, Inbred Strains

6.

The effect of phenmetrazine on performance of irradiated rats.

Tusl, M; Obrsál, J; Bergerová, M; Svorcová, S.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 28(1-2): 117-26, 1985.

Article in English | MEDLINE | ID: mdl-3870439

Subject(s)

Behavior, Animal/drug effects , Phenmetrazine/pharmacology , Radiation Injuries, Experimental/physiopathology , Animals , Female , Rats , Rats, Inbred Strains

7.

The effect of chronic exposure to 20 mg. per cubic meter NOx on the hormonal and enzymatic changes in rats.

Vyskocil, A; Obrsál, J; Tusl, M; Cerman, J; Suba, P.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 27(2): 253-7, 1984.

Article in English | MEDLINE | ID: mdl-6599641

Subject(s)

Lung/metabolism , Nitrous Oxide/toxicity , Animals , Corticosterone/metabolism , Histamine/metabolism , Lung/enzymology , Male , Rats , Rats, Inbred Strains , Superoxide Dismutase/metabolism , Thyroxine/metabolism , Time Factors

8.

[Methods of determining centrophenoxine and p-chlorphenoxyacetic acid]. / Metodika stanovení centrophenoxinu a kyseliny p-chlorfenoxyoctové.

Obrsál, J.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 26(3): 243-53, 1983.

Article in Czech | MEDLINE | ID: mdl-6442462

Subject(s)

2,4-Dichlorophenoxyacetic Acid/analogs & derivatives , Glycolates/analysis , Meclofenoxate/analysis , 2,4-Dichlorophenoxyacetic Acid/analysis , Chromatography, Gas

9.

The distribution of caffeine in rats after irradiation.

Obrsál, J; Tusl, M.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 26(5): 611-7, 1983.

Article in English | MEDLINE | ID: mdl-6599178

Subject(s)

Caffeine/radiation effects , Animals , Caffeine/metabolism , Female , Rats , Rats, Inbred Strains , Tissue Distribution , X-Rays

10.

The effect of irradiation on the distribution of phenmetrazine in rats.

Obrsál, J; Tusl, M.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 26(5): 619-29, 1983.

Article in English | MEDLINE | ID: mdl-6599179

Subject(s)

Phenmetrazine/radiation effects , Animals , Female , Phenmetrazine/metabolism , Rats , Rats, Inbred Strains , Time Factors , Tissue Distribution , X-Rays

11.

[Changes in the distribution of methylphenidate in rats after irradiation]. / Zmeny distribuce metylfenidátu u krys po ozárení.

Obrsál, J; Tusl, M.

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 26(3): 255-65, 1983.

Article in Czech | MEDLINE | ID: mdl-6335785

Subject(s)

Methylphenidate/radiation effects , Animals , Male , Methylphenidate/metabolism , Rats , Rats, Inbred Strains , Tissue Distribution , X-Rays

ABSTRACT

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

Subject(s)

SEND TO:

SELECTION OF CITATIONS

SEARCH DETAIL