ABSTRACT
The most sensitive indices of the blood system at EMF exposure (disorders of megakaryocytes differentiation, unspecific reactions, repopulation of the blasts cells a. al.) have been determined by the cytologic investigations. At has been revealed that allowable UVF levels effect are situated below the threshold of activisation of adaptive reactions (less than 0.01 mV/cm2), for occupational conditions--at the level of compensatory processes (0.05-0.1 mV/cm2). The intensities higher than 0.5 mV/cm2 were estimated as critical. Involution of megakaryocytes, polimorphism and disturbances the structure of leucocytes a. al. were revealed as EMF markers which allow to carry out an express-diagnostic.
Subject(s)
Cells/radiation effects , Electromagnetic Fields , Immune System/radiation effects , Adaptation, Physiological , Animals , Cytophotometry , DNA/radiation effects , Leukocytes/radiation effects , Male , Megakaryocytes/radiation effects , Polymorphism, Genetic , Radiation Dosage , Rats , Rats, Inbred F344 , Rats, Wistar , Spleen/radiation effects , Thymus Gland/radiation effects , Time FactorsSubject(s)
Air Pollution/analysis , Coal Tar , Environmental Exposure , Volatilization , Animals , Humans , Lethal Dose 50 , Maximum Allowable Concentration , Mice , Mice, Inbred CBA , Rabbits , RatsABSTRACT
DNA content of nondifferentiated and blast bone marrow cells was studied cytophotometrically after single exposure to SHF-radiation. It is supposed that cell adaptive reactions in blood system are responsible for phase changes in DNA quantity, the passage of cells through the mitotic cycle and their proliferative activity.
Subject(s)
Bone Marrow/radiation effects , DNA/radiation effects , Microwaves/adverse effects , Animals , Bone Marrow Cells , Cell Cycle/radiation effects , Cytophotometry , Male , Mitosis/radiation effects , Rats , Rats, Inbred Strains , Time FactorsABSTRACT
Changes in mitotic activity of myelocaryocytes exposed to super-high frequency field (2375 MHz) of 10, 50 and 500 microW/cm2 for a month show the influence of this factor on the DNA synthesis, premitotic processes and cell reproduction biorhythms depending on the radiation intensity.