Air-filled SIW technology for mass-manufacturable and energy-efficient terahertz systems.

To accommodate the ever-growing data requirements in densely populated areas and address the need for high-resolution sensing in diverse next-generation applications, there is a noticeable trend towards utilizing large unallocated frequency bands above 100 GHz. To overcome the harsh propagation conditions, large-scale antenna arrays are crucial and urge the need for cost-effective, mass-manufacturable technologies. A dedicated Any-Layer High Density Interconnect PCB technology for highly efficient wireless D-band (110-170 GHz) systems is proposed. Specifically, the adapted stack accommodates broadband air-filled substrate-integrated-waveguide components for efficient long-range signal distribution and low-loss passives. The viability of the suggested technology platform is demonstrated by designing, fabricating and measuring several essential low-loss air-filled substrate-integrated-waveguide components, such as a dual rectangular filter, with a minimal insertion loss of 0.87 dB and 10 dB-matching within the (132.8-139.2 GHz) frequency band, and an air-filled waveguide with a routing loss of only 0.08 dB/mm and a flat amplitude variation within 0.01 dB/mm over the (115-155 GHz) frequency range. A broadband transition towards stripline, with a limited loss of 1.1 dB, is described to interface these waveguides with compactly integrated chips. A tolerance analysis is included as well as a comparison to the state of the art.

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively.

In this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz. At high frequencies (from tens of MHz to GHz), the electromagnetic signal passes through the membrane and allows probing the cytoplasm. This enables several applications, such as cell classification, and viability analysis. Additionally, the use of conventional microfabrication techniques reduces the cost and complexity of analysis, compared to other non-invasive methods. We demonstrated the potential of this set-up by identifying two different populations of T-lymphocytes not distinguishable through visual assessment. We also assessed the effect of calcein on cell cytoplasmic properties and used it as a controlled experiment to demonstrate the possibility of this method to detect changes happening predominantly in the cytoplasm.

Improving the Accuracy of Spiking Neural Networks for Radar Gesture Recognition Through Preprocessing.

Event-based neural networks are currently being explored as efficient solutions for performing AI tasks at the extreme edge. To fully exploit their potential, event-based neural networks coupled to adequate preprocessing must be investigated. Within this context, we demonstrate a 4-b-weight spiking neural network (SNN) for radar gesture recognition, achieving a state-of-the-art 93% accuracy within only four processing time steps while using only one convolutional layer and two fully connected layers. This solution consumes very little energy and area if implemented in event-based hardware, which makes it suited for embedded extreme-edge applications. In addition, we demonstrate the importance of signal preprocessing for achieving this high recognition accuracy in SNNs compared to deep neural networks (DNNs) with the same network topology and training strategy. We show that efficient preprocessing prior to the neural network is drastically more important for SNNs compared to DNNs. We also demonstrate, for the first time, that the preprocessing parameters can affect SNNs and DNNs in antagonistic ways, prohibiting the generalization of conclusions drawn from DNN design to SNNs. We demonstrate our findings by comparing the gesture recognition accuracy achieved with our SNN to a DNN with the same architecture and similar training. Unlike previously proposed neural networks for radar processing, this work enables ultralow-power radar-based gesture recognition for extreme-edge devices.

Automatic radar-based 2-D localization exploiting vital signs signatures.

In light of the continuously and rapidly growing senior and geriatric population, the research of new technologies enabling long-term remote patient monitoring plays an important role. For this purpose, we propose a single-input-multiple-output (SIMO) frequency-modulated continuous wave (FMCW) radar system and a signal processing technique to automatically detect the number and the 2-D position (azimuth and range information) of stationary people (seated/lying down). This is achieved by extracting the vital signs signatures of each single individual, separating the Doppler shifts caused by the cardiopulmonary activities from the unwanted reflected signals from static reflectors and multipaths. We then determine the number of human subjects present in the monitored environment by counting the number of extracted vital signs signatures while the 2-D localization is performed by measuring the distance from the radar where the vital signs information is sensed (i.e., locating the thoracic region). We reported maximum mean absolute errors (MAEs) of 0.1 m and 2.29[Formula: see text] and maximum root-mean-square errors (RMSEs) of 0.12 m and 3.04[Formula: see text] in measuring respectively the ranges and azimuth angles. The experimental validation demonstrated the ability of the proposed approach in monitoring paired human subjects in a typical office environment.

Effect of Open-Ended Coaxial Probe-to-Tissue Contact Pressure on Dielectric Measurements.

Open-ended coaxial probes are widely used to gather dielectric properties of biological tissues. Due to the lack of an agreed data acquisition protocol, several environmental conditions can cause inaccuracies when comparing dielectric data. In this work, the effect of a different measurement probe-to-tissue contact pressure was monitored in the frequency range from 0.5 to 20 GHz. Therefore, we constructed a controlled lifting platform with an integrated pressure sensor to exert a constant pressure on the tissue sample during the dielectric measurement. In the pressure range from 7.74 kPa to 77.4 kPa, we observed a linear correlation of - 0 . 31 ± 0 . 09 % and - 0 . 32 ± 0 . 14 % per kPa for, respectively, the relative real and imaginary complex permittivity. These values are statistically significant compared with the reported measurement uncertainty. Following the literature in different biology-related disciplines regarding pressure-induced variability in measurements, we hypothesize that these changes originate from squeezing out the interstitial and extracellular fluid. This process locally increases the concentration of membranes, cellular organelles, and proteins in the sensed volume. Finally, we suggest moving towards a standardized probe-to-tissue contact pressure, since the literature has already demonstrated that reprobing at the same pressure can produce repeatable data within a 1% uncertainty interval.

Novel Fabrication Process for Integration of Microwave Sensors in Microfluidic Channels.

This paper presents a novel fabrication process that allows integration of polydimethylsiloxane (PDMS)-based microfluidic channels and metal electrodes on a wafer with a micrometer-range alignment accuracy. This high level of alignment accuracy enables integration of microwave and microfluidic technologies, and furthermore accurate microwave dielectric characterization of biological liquids and chemical compounds on a nanoliter scale. The microfluidic interface between the pump feed lines and the fluidic channels was obtained using magnets fluidic connection. The tube-channel interference and the fluidic channel-wafer adhesion was evaluated, and up to a pressure of 700 mBar no leakage was observed. The developed manufacturing process was tested on a design of a microwave-microfluidic capacitive sensor. An interdigital capacitor (IDC) and a microfluidic channel were manufactured with an alignment accuracy of 2.5 µm. The manufactured IDC sensor was used to demonstrate microwave dielectric sensing on deionized water and saline solutions with concentrations of 0.1, 0.5, 1, and 2.5 M.

A Microwave Platform for Reliable and Instant Interconnecting Combined with Microwave-Microfluidic Interdigital Capacitor Chips for Sensing Applications.

This work presents a novel platform conceived as an interconnect box (ICB) that brings high-frequency signals from microwave instruments to consumable lab-on-a-chip devices. The ICB can be connected to instruments with a standard coaxial connector and to consumable chips by introducing a spring-levered interface with elastomer conductive pins. With the spring-system, microwave-microfluidic chips can be mounted reliably on the setup in a couple of seconds. The high-frequency interface within the ICB is protected from the environment by an enclosure having a single slit for mounting the chip. The stability and repeatability of the contact between the ICB and inserted consumable chips are investigated to prove the reliability of the proposed ICB. Given the rapid interconnecting of chips using the proposed ICB, five different interdigital capacitor (IDC) designs having the same sensing area were investigated for dielectric permittivity extraction of liquids. The designed IDCs, embedded in a polydimethylsiloxane (PDMS) channel, were fabricated with a lift-off gold patterning technology on a quartz substrate. Water-Isopropanol (IPA) mixtures with different volume fractions were flushed through the channel over IDCs and sensed based on the measured reflection coefficients. Dielectric permittivity was extracted using permittivity extraction techniques, and fitted permittivity data shows good agreement with literature from 100 to 25 GHz.

An Interdigital Capacitor for Microwave Heating at 25 GHz and Wideband Dielectric Sensing of nL Volumes in Continuous Microfluidics.

This paper proposes a miniature microwave-microfluidic chip based on continuous microfluidics and a miniature interdigital capacitor (IDC). The novel chip consists of three individually accessible heaters, three platinum temperature sensors and two liquid cooling and mixing zones. The IDC is designed to achieve localized, fast and uniform heating of nanoliter volumes flowing through the microfluidic channel. The heating performance of the IDC located on the novel chip was evaluated using a fluorescent dye (Rhodamine B) diluted in demineralized water on a novel microwave-optical-fluidic (MOF) measurement setup. The MOF setup allows simultaneous microwave excitation of the IDC by means of a custom-made printed circuit board (connected to microwave equipment) placed in a top stage of a microscope, manipulation of liquid flowing through the channel located over the IDC with a pump and optical inspection of the same liquid flowing over the IDC using a fast camera, a light source and the microscope. The designed IDC brings a liquid volume of around 1.2 nL from room temperature to 100 °C in 21 ms with 1.58 W at 25 GHz. Next to the heating capability, the designed IDC can dielectrically sense the flowing liquid. Liquid sensing was evaluated on different concentration of water-isopropanol mixtures, and a reflection coefficient magnitude change of 6 dB was recorded around 8.1 GHz, while the minimum of the reflection coefficient magnitude shifted in the same frequency range for 60 MHz.

A Modeling Procedure of the Broadband Dielectric Spectroscopy for Ionic Liquids.

The dielectric spectroscopy (DS) measurement is an attractive noninvasive method to reveal the intrinsic information of biological materials and cell cultures. However, the presence of a double layer due to electrode polarization within the lower RF and microwave range significantly affects the accurate analysis of dielectric properties of ionic liquids. In this paper, we measure the broadband DS of five saline solutions with a microfluidic coplanar waveguide (CPW) transmission line sensor across the frequency range from 40 kHz to 110 GHz. Derived from a parallel-plate structure that is transformed from the quasi-TEM CPW sensor through a conformal mapping technique, a broadband spectroscopy modeling method is proposed, where a Cole-Cole function or a constant phase element formula is used depending on the ionic concentrations and the measurement window. Validation analysis on the five saline solutions demonstrates the capability of the modeling method in separating relaxation properties of the bulk sample from the double-layer effects.

A system-level simulator for indoor mmW SAR imaging and its applications.

Recently, the research interest in indoor active millimeter wave (mmW) imaging by applying the synthetic aperture radar (SAR) technique is increasing. However, there is a lack of proper computer-aided design (CAD) tools at the system level, and almost all the R&D activities rely on experiments solely. The high cost of such a system stops many researchers from investigating such a fascinating research topic. Moreover, the experiment-oriented studies may blind the researchers to some details during the imaging process, since in most cases they are only interested in the readout from the receivers and do not know how the waves perform in reality. To bridge such a gap, we propose a modeling approach at mmW frequencies, which is able to simulate the physical process during SAR imaging. We are not going to discuss about advanced image reconstruction algorithms, since they have already been investigated intensively for decades. To distinguish from previous work, for the first time, we model the data acquisition process in a SAR imaging system successfully at mmW frequencies. We show how to perform some system-level studies based on such a simulator via a common PC, including the influence of reflectivity contrast between object and background, sampling step, and antenna's directivity on image quality. The simulator can serve system design purposes and it can be easily extended to THz frequencies.

Millimeter wave imaging system modeling: spatial frequency domain calculation versus spatial domain calculation.

Active millimeter wave imaging systems have become a promising candidate for indoor security applications and industrial inspection. However, there is a lack of simulation tools at the system level. We introduce and evaluate two modeling approaches that are applied to active millimeter wave imaging systems. The first approach originates in Fourier optics and concerns the calculation in the spatial frequency domain. The second approach is based on wave propagation and corresponds to calculation in the spatial domain. We compare the two approaches in the case of both rough and smooth objects and point out that the spatial frequency domain calculation may suffer from a large error in amplitude of 50% in the case of rough objects. The comparison demonstrates that the concepts of point-spread function and f-number should be applied with careful consideration in coherent millimeter wave imaging systems. In the case of indoor applications, the near-field effect should be considered, and this is included in the spatial domain calculation.

Study of active millimeter-wave image speckle reduction by Hadamard phase pattern illumination.

Active millimeter-wave images typically exhibit characteristic speckle noise, due to the coherence of artificial millimeter-wave sources. We study the Hadamard speckle contrast reduction (SCR) technique, which has been successfully used in laser projection systems, in the context of millimeter-wave imaging. We show the impact of Hadamard pattern order and size and of image and pattern resolution on speckle reduction efficiency. Practical limitations of Hadamard pattern implementations and their effect on speckle reduction efficiency are also discussed.