Morphological peculiarities of the autonomic nervous system in the thoracic region.

BACKGROUND: The aim of the work is to define the morphological peculiarities of the autonomic nervous system (ANS) in the thoracic region. MATERIAL AND METHODS: An anatomical study was performed on 20 cadavers, 17 men and 3 women. We studied cadavers within 24 h of death. We observed the vertebral and prevertebral section of the truncus sympathicus, their morphological peculiarities depending on the type of ANS. To show the intimate relationship of both systems, we also focused on the details of the structure related to the connections of the ANS with the spinal nervous system. RESULTS: In the thoracic region, the segmental arrangement of the truncus sympathicus ganglia prevailed in 16 (80%) cases. Rami communicantes gave anastomoses to spinal nerves. Small ganglia were observed on the rami communicantes to the spinal nerves. In the case of the concentrated type, in 4 cases (20%), we observed a reduction in the number of ganglia, as well as the absence of small ganglia on the connecting branches. Connections between n. vagus and sympathetic branches were poorly developed. We observed right-left asymmetry and differences in the formation of ganglia and anastomoses in the truncus sympathicus in the vertebral and prevertebral section. Variations of distance of n. splanchnicus major were observed in 16 cases (80%). CONCLUSION: This study allowed us to identify and describe the morphological peculiarities of the thoracic ANS. The variations were numerous; their preoperative diagnosis is difficult to impossible. The knowledge gained can be helpful in clarifying clinical signs and symptoms.

Unusual mechanism of injury in a case of suicide by the jump from height.

Investigation of fatal cases of falls from height as well as jumps from height in suicidal ideation makes up an integral part of forensic practice. In Slovakia, a method of suicide by jumping from height is after hanging the second most chosen method of ending life. In about one third of the cases, the influence of addictive substances is determined. The basic mechanism of injury is a sudden deceleration of body movement when hitting a solid surface. Several factors influence the nature, localization, severity, and frequency of injuries. In most cases, there occur multiple injuries to the skeleton and internal organs caused by blunt objects. The authors demonstrate the case of an unusual mechanism of injury in a 55-year-old man who committed suicide by jumping from the seventh floor of a block of flats. A stepped fall from height resulted in the through knee amputation of both legs by hitting posterior thigh area and knee joints on the railing of the terrace of the block of flats on the ground floor level. The body was found in the basement. In contact with the railing, the mans trousers and pants were pulled off. The autopsy determined the immediate cause of death as polytrauma. Additional toxicological-chemical examination of blood and urine samples collected at autopsy revealed ethanol at the concentration within the extent of laboratory error, caffeine, and nicotine in toxicologically insignificant concentrations and traces of acetone. Motivation of mans suicide remains unknown.

[Parallel investigations of blood and alveolar air in the diagnosis of lethal carbon monoxide poisoning]. / Súbezné vysetrovanie krvi a alveolárneho vzduchu v diagnostike letálnych intoxikácií oxidom uholnatým.

Carbon monoxide poisonings are the most frequent among fatal gas and volatile substances intoxications. The authors present diagnostic options of fatal carbon monoxide poisoning by parallel blood investigations for the content of karbonylhaemoglobin and determining of the concentration of carbon monoxide in the alveolar air. The analysis of 160 cases of lethal poisonings with carbon monoxide over a period of 20 years was carried out. The cases were divided into subgroups according to the place of death to poisonings in flats, garages, bathrooms, in fires, road traffic accidents and mining accidents. Tabular cases were divided into poisonings with a dominant share of carbon monoxide; the lethal concentration (0.075 % volume percentage or more) in the alveolar air was found in 75 % of cases. By pairs of victims different concentrations of carbon monoxide in the alveolar air were found. It confirms the fact that the course of intoxication and time of death also depends on the state of health of an individual. In 25 % of cases composite action with other toxic substances and factors (cyanide ions, ethanol, carbon dioxide, smoke inhalation solids, burns etc.) was detected. The obtained results point to an important and irreplaceable role of the toxicological - chemical analysis of the alveolar air in the context of additional laboratory investigations at autopsy in the diagnosis of fatal carbon monoxide poisoning. Investigation of the alveolar air should be the standard methodological procedure in the diagnosis of fatal poisonings by gases and volatile substances.

[Addictive substances in fatal cases of fall/jump from height]. / Návykové látky vo fatálnych prípadoch pádov/skokov z výsky.

The aim of the study is to analyse causes of fatal cases of falls from height focusing on the occurrence of addictive substances. The authors performed a retrospective analysis of cases dealing with falls/jumps autopsied at the Institutes of Forensic Medicine in Bratislava in the years 2005-2014 accounting for a catchment area with approximately 1.2 m population. Selection criteria were met in 360 cases, i.e. approximately 4 % of all cases autopsied. There were 68 % of men and 32 % of women involved. The age interval ranged from 10 up to 93 years (mean age 50 years). Addictive substances were found in a total of 32 % of cases, ethanol alone in 22 % of cases. The cases were divided into groups according to the cause as follows: accidental falls (24%) also involving occupational accidents (11 %), jumps in suicidal ideation (63 %) and cases with the unspecified cause of falling (13 %). Most of the cases with detected addictive substances were in the group of suicidal jumps (35 %). In this group, 32 % of patients were treated for psychiatric disorders. The most common diagnosis was a depressive disorder and schizophrenia. In the group of occupational accidents, ethanol was found in 25 % of cases. The results of the study show that it is essential to pay more attention to psychiatric patients as not even regular psychiatric care and treatment can always prevent suicide. Accordingly, there is a need to strictly monitor the ban on alcohol consumption at work and the observance of safety regulations for working at heights, and thus to minimise the occurrence of falls with fatal outcomes.