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2.
J Osaka Univ Dent Sch ; 29: 117-22, 1989 Dec.
Article in English | MEDLINE | ID: mdl-2577382

ABSTRACT

The cellular immunity of peripheral blood was analyzed to evaluate the efficacy of OK-432 between 3 groups of patients with oromaxillary squamous cell cancer, which were composed of 14 patients in the pretreatment stage, 8 patients who were free from cancer more than one year after the last cancer therapy and had been continuously treated with OK-432, and 14 patients who had undertaken cancer therapy without OK-432 and were also free from cancer for at least one year. As parameters of cellular immunity, leucocyte counts, percent composition of T-cells, percent compositions of T-lymphocyte subsets (OKIal+, OKT3+, OKT4+, and OKT8+) and the ratio of OKT4+ and OKT8+, PPD skin test, and lymphocytic blastogenesis induced by PHA and Con-A, were examined. The results showed no significant difference between the patients treated with and without OK-432. Nor was there any significant difference between the pretreatment group and the posttreatment groups with and without OK-432 treatments in any of the examined immunologic parameters.


Subject(s)
Carcinoma, Squamous Cell/therapy , Immunity, Cellular/drug effects , Jaw Neoplasms/therapy , Mouth Neoplasms/therapy , Picibanil/therapeutic use , Adult , Aged , CD4-Positive T-Lymphocytes/drug effects , Carcinoma, Squamous Cell/immunology , Female , Humans , Immunotherapy , Jaw Neoplasms/immunology , Leukocyte Count/drug effects , Lymphocyte Activation/drug effects , Male , Middle Aged , Mouth Neoplasms/immunology , T-Lymphocytes, Regulatory/drug effects
3.
J Oral Maxillofac Surg ; 47(9): 907-12, 1989 Sep.
Article in English | MEDLINE | ID: mdl-2668468

ABSTRACT

Ultrasound examination for sialolithiasis was carried out in ten cases, and the findings were compared with those from sialography. Salivary stones were recognized as high-level reverberation echoes accompanied by posterior acoustic shadows in eight cases, whereas in the remaining two they appeared only as hyperechoic masses. In a case of sialolithiasis of the parotid gland that was difficult to detect by simple radiographic examination, a salivary stone was detected by both sialographic and ultrasonographic examination. Clearly separated salivary stones were also easily detected in each case by the ultrasonographic method, but multiple, gathered calculi were not precisely detected. The smallest sialolith that could be detected was approximately 2 x 3 mm in size. The rate of detection of salivary stones by using the ultrasonographic method was as high as that from using sialography. Because the examination is simple and noninvasive, its use to evaluate sialolithiasis is probably indicated more frequently, especially when there is acute infection in the gland.


Subject(s)
Salivary Gland Calculi/diagnosis , Salivary Glands/pathology , Ultrasonography , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Male , Salivary Gland Calculi/diagnostic imaging , Sialography
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