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1.
Nanotechnology ; 21(49): 495304, 2010 Dec 10.
Article in English | MEDLINE | ID: mdl-21079291

ABSTRACT

It is of great interest and importance to develop new nanofabrication processes to fabricate sub-20 nm structures with sub-2 nm resolution for next-generation nanoelectronic devices. A combination of electron beam lithography (EBL) and a molecular ruler is one of the promising methods to make these fine structures. Here we successfully develop a hybrid method to fabricate sub-20 nm nanogap devices at the desired positions with a complex structure by developing a post-EBL process, which enabled us to avoid damaging the molecular ruler with the high-energy electron beam, and to fully utilize the EBL resolution. It was found that slight etching of the Ti adhesion layer of the parent metal (Pt) by ACT935J solution assisted the removal of molecular rulers, resulting in improved enhancement in the product yield (over 70%) of nanogap devices.

10.
Jikken Dobutsu ; 24(2): 41-4, 1975 Apr.
Article in Japanese | MEDLINE | ID: mdl-1171765

ABSTRACT

Hymenolepis nana (von Siebold, 1852), the dwarf tapeworm causing hymenolepiasis, has been reported to be the common intestinal cestode of rodents and man throughout the world. The authors found spontaneously occurred hymenolepiasis in conventional laboratory hamsters with mass and heavy infections. Some individuals were infected with as many as 188 to 290 worms and in addition, numerous cysticercoids were found in the intestinal villi from the same hamsters. According to the early investigations it is said that there are two ways of infection to rodents. In this study the authors considered a natural autoinfection is to be the case because cysticercoids and immature worms were abundant in the intestines of hamsters. The infection rate of the hamsters was 15% as 6 hamsters were found infected out of 40. All the cases of the heavily infected hamsters showed showed loss of weight and some of them died. Particular damage of the intestinal mucosa was not seen by post-mortem examinations, however, chronic inflammation and destruction of intestinal mucosa caused by the worms observed microscopically (the given pictures). Heavy infection of Hymenolepis nana occurred spontaneously in hamsters has rarely been found in Japan. The case reported here seems to be very peculiar one.


Subject(s)
Animals, Laboratory/parasitology , Cricetinae/parasitology , Hymenolepiasis/veterinary , Rodent Diseases/parasitology , Animals , Female , Intestinal Mucosa/parasitology , Male
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