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[Binding of LPS to CD14]. / Bindungsmodalitäten von LPS an CD14.

Grunwald, U; Oeser, G; Schröder, H D; Ritscher, D; Schütt, C.

Immun Infekt ; 20(3): 86-7, 1992 Jul.

Article in German | MEDLINE | ID: mdl-1379976

ABSTRACT

The 53 kDa glycoprotein CD14 (cluster of differentiation No. 14, defined by monoclonal antibodies of the 1st Leukocyte Typing Workshop) is expressed on monocyte surfaces and was identified 1990 as an endotoxin receptor (1). The binding of endotoxin to CD14 was mediated by a LPS-binding protein (LBP) present in serum.

Subject(s)

Antigens, CD/metabolism , Antigens, Differentiation, Myelomonocytic/metabolism , Blood Proteins/metabolism , Lipopolysaccharides/metabolism , Monocytes/metabolism , Animals , Antibodies, Monoclonal/metabolism , Humans , Lipopolysaccharide Receptors , Protein Binding , Receptors, Immunologic/metabolism , Species Specificity

ABSTRACT

Subject(s)

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