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1.
Ann Surg Treat Res ; 100(5): 291-297, 2021 May.
Article in English | MEDLINE | ID: mdl-34012947

ABSTRACT

PURPOSE: Ruptured abdominal aortic aneurysm (rAAA) is one of the most common aortic emergencies in vascular surgery and is associated with high operative mortality and morbidity rates despite recent treatment advances. We evaluated operative mortality risks for the outcomes of emergency endovascular aneurysm repair (eEVAR) vs. open repair in rAAA. METHODS: Twenty patients underwent eEVAR (n = 12) or open repair (n = 8) for rAAA between 2016 and 2020. We adopted the EVAR first strategy since 2018. Primary endpoints included in-hospital mortality and 1-year survival. The outcome variables were analyzed with Fisher exact, Mann-Whitney test, and linear by linear association. The Kaplan-Meier method was used to estimate survival. RESULTS: There were 13 males (65.0%) and the median age of the study cohort was 78.0 years (range, 49-88 years). In-hospital mortality occurred in 7 patients (35.0%); 5 (50.0%) in the early period and 2 (20.0%) in the later period of this series. According to the procedure type, 4 (50.0%) and 3 (25.0%) in-hospital mortalities occurred in the open repair and eEVAR patients, respectively. In 6 patients (50.0%), eEVAR was performed on unfavorable anatomy. The 1-year survival of eEVAR vs. open repair group was 75% ± 12.5% and 50% ± 17.7%, respectively. On univariate analysis, preoperative high-risk indices, postoperative acute renal failure requiring dialysis, pulmonary complications, and prolonged mechanical ventilation were associated with higher operative mortality. CONCLUSION: The current data showed relatively superior outcomes with eEVAR vs. open repair for rAAA, even in some patients with unfavorable anatomy supporting the feasibility, efficacy, and safety of EVAR first strategy.

2.
Ann Thorac Surg ; 112(3): 803-808, 2021 09.
Article in English | MEDLINE | ID: mdl-33157062

ABSTRACT

BACKGROUND: The edge-to-edge technique (Alfieri stitch) has been widely adopted in mitral valve but not tricuspid valve (TV) repair. We evaluated long-term clinical and hemodynamic outcomes of tricuspid edge-to-edge repair. METHODS: We retrospectively reviewed 237 patients (mean age, 58.4 ± 13.9 years) who had undergone tricuspid edge-to-edge repair from January 2001 to March 2019 in our institution. Tricuspid annuloplasty was performed in 175 patients (73.8%) using ring (91 [38.4%]) or suture (84 [35.4%]) annuloplasty. Concomitant procedures were mitral valve replacement (133 [56.1%]), mitral valve repair (52 [21.9%]), aortic valve replacement (41 [17.3%]), and maze operation (138 [58.2%]). RESULTS: Postoperative echocardiography revealed mild or less tricuspid regurgitation (TR) in 220 patients (92.8%). Early mortality (<30 days) occurred in 9 patients (3.8%), reoperation for bleeding in 16 (6.8%), and low cardiac output syndrome in 15 (6.4%). Freedom from all-cause mortality was 87.2% at 5 years and 80.6% at 10 years. Freedom from moderate or severe TR was 97.1% at 5 years and 84.9% at 10 years. Transtricuspid pressure gradient was 3.8 ± 4.2 mm Hg at discharge and 3.2 ± 5.6 mm Hg at the last follow-up (P = .60). Freedom from significant tricuspid stenosis (transtricuspid pressure gradient ≥5 mm Hg) was 96.4% and 88.4% at 5 and 10 years, respectively. There was 1 early TV reoperation for severe TR on postoperative day 3 (0.4%). Freedom from TV reoperation was 99.1% at 10 years. CONCLUSIONS: Tricuspid edge-to-edge repair showed acceptable long-term clinical and hemodynamic results and is an effective and safe option in TV surgery.


Subject(s)
Tricuspid Valve Insufficiency/surgery , Aged , Cardiac Surgical Procedures/methods , Female , Hemodynamics , Humans , Male , Middle Aged , Retrospective Studies , Time Factors , Treatment Outcome
3.
Korean J Thorac Cardiovasc Surg ; 51(4): 231-240, 2018 Aug.
Article in English | MEDLINE | ID: mdl-30109200

ABSTRACT

BACKGROUND: Analyses of the efficacy and safety of transcatheter aortic valve replacement (TAVR) in most countries have been based on outcomes obtained in accordance with national practice guidelines and monitoring protocols. The purpose of this study is to share our experience regarding the process for establishing guidelines and monitoring protocols for the use of TAVR in Korea, in the hopes that it may be helpful to others undergoing a similar process in their own country. METHODS: The Korean guidelines for TAVR were established on June 1, 2015 in through a tri-party agreement involving the Department of Health and Welfare, the Korean Society of Thoracic and Cardiovascular Surgery and the Korean Society of Cardiology. We agreed to monitor the guidelines transparently and to exchange opinions regarding amendments or continuation of its contents after 3 years of monitoring. RESULTS: The monitoring meetings were not held as regularly as agreed, and monitoring was also made difficult by insufficient and incomplete data. Nevertheless, during the meetings, measures to improve the monitoring process were discussed, and accordingly, an agreement was made to continue the monitoring process, with the aim of completing data collection by 2018. CONCLUSION: Compliance with guidelines is critical for assessing the efficacy and safety of TAVR. Moreover, the TAVR monitoring process must be properly conducted for an accurate evaluation to be made. Any country planning to introduce TAVR may encounter difficulties with regards to the optimal initiation strategy and subsequent monitoring. Nevertheless, continued efforts should be made to persuade the government and the corresponding medical societies to facilitate the optimal application of TAVR.

5.
J Cardiovasc Ultrasound ; 24(1): 79-83, 2016 Mar.
Article in English | MEDLINE | ID: mdl-27081451

ABSTRACT

Stress-induced cardiomyopathy has become a more recognized and reported entity. It can be caused by emotional or physical stress, which causes excessive catecholamine release. Typically, the clinical course is benign with conservative treatment being effective. However, stress-induced cardiomyopathy can be fatal. A 41-year-old female presented with cardiogenic shock followed by sudden back pain. Initial echocardiographic finding showed severely decreased ejection fraction with akinesia at all mid-to-apical walls with relatively preserved basal wall contractility. The coronary artery was intact on coronary angiography. Cardiac resuscitation and extra-corporeal membrane oxygenation was needed to manage the cardiogenic shock. Recovery was complete after 2 weeks.

6.
Biomed Res Int ; 2014: 254187, 2014.
Article in English | MEDLINE | ID: mdl-25110667

ABSTRACT

BACKGROUND: The use of anticoagulant therapy (ACT) in patients with acute infective endocarditis (IE) remains a controversial issue. Our study attempts to estimate the impact of ACT on the occurrence of embolic complications and the usefulness of ACT in the prevention of embolism in IE patients. METHODS: The present authors analyzed 150 patients with left-sided IE. Embolisms including cerebrovascular events (CVE) and the use of ACT were checked at the time of admission and during hospitalization. RESULTS: 57 patients (38.0%) experienced an embolic event. There was no significant difference in the incidence of CVE and in-hospital mortality between patients with and without warfarin use at admission, although warfarin-naïve patients were significantly more likely to have large (>1 cm) and mobile vegetation. In addition, there was no significant difference in the incidence of postadmission embolism and in-hospital death between patients with and without in-hospital ACT. On multivariate logistic regression analysis, ACT at admission was not significantly associated with a lower risk of embolism in patients with IE. CONCLUSIONS: The role of ACT in the prevention of embolism was limited in IE patients undergoing antibiotic therapy, although it seems to reduce the embolic potential of septic vegetation before treatment.


Subject(s)
Anticoagulants/therapeutic use , Embolism/etiology , Embolism/prevention & control , Endocarditis, Bacterial/complications , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Child , Embolism/drug therapy , Female , Hospitalization , Humans , Kaplan-Meier Estimate , Male , Middle Aged , Risk Factors , Time Factors , Young Adult
7.
BMC Neurol ; 14: 30, 2014 Feb 15.
Article in English | MEDLINE | ID: mdl-24528538

ABSTRACT

BACKGROUND: Cerebrovascular complications (CVCs) frequently occur in patients with acute infective endocarditis (IE). The aim of this study is to describe the clinical findings of CVCs and to evaluate the impact of CVCs on long-term mortality in patients with IE. METHODS: We retrospectively analyzed 144 patients who fulfilled the modified Duke's criteria for definite left-sided IE. CVCs were classified into minor (silent cerebral embolism, TIA and stroke with an initial modified Rankin scale ≤ 2) or major (an initial modified Rankin scale ≥ 3) CVCs. Cox proportional hazards model was used for mortality analysis. Hazard ratio (HR) and 95% confidence interval (CI) were obtained. RESULTS: The mean age of the 144 patients (96 males and 48 females) was 49.1 years (range 6-85 years). A CVC was found in 37 (25.7%) patients. Of these, 25 were treated with surgical therapy. The patients who underwent early surgery within 2 weeks after stroke had a statistical trend toward a higher risk of postoperative brain hemorrhage (50% versus 4.8%, P = 0.057 by Fisher exact test). The minor CVC group had a similar risk of death as the no-CVC group (P = 0.803; HR 0.856; CI 0.253-2.894), whereas the major CVC group had a higher mortality (P = 0.013; HR 2.865; CI 1.254-6.548) than the no-CVC group. In the multivariate analysis, major CVC (P = 0.002; HR 3.893; CI 1.649-9.194) was a significant predictor of mortality in IE patients, together with advanced age (P = 0.005; HR 3.138; CI 1.421-6.930) and prosthetic valve IE (P = 0.008; HR 2.819; CI 1.315-6.044). CONCLUSIONS: IE can give rise to various forms of CVC, most frequently, acute ischemic brain lesions. In our study, major CVC was associated with high risk of mortality although total CVC was not significantly related to the risk of death in patients with IE.


Subject(s)
Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/epidemiology , Endocarditis/diagnosis , Endocarditis/epidemiology , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Male , Middle Aged , Retrospective Studies , Time Factors , Young Adult
8.
Korean J Thorac Cardiovasc Surg ; 46(4): 256-64, 2013 Aug.
Article in English | MEDLINE | ID: mdl-24003406

ABSTRACT

BACKGROUND: Surgical treatment of infective endocarditis (IE) remains a challenge, especially in cases of multiple valve surgery. We evaluated the clinical outcomes of native valve IE and compared the outcomes of single valve surgery with those of multiple valve surgery. MATERIALS AND METHODS: From 1997 to 2011, 90 patients underwent surgery for native valve IE; 67 patients with single valve surgery (single valve group) and 23 patients with multiple valve surgery (multiple valve group). The mean follow-up duration was 73.1±47.4 months. RESULTS: The surgical mortality in the total cohort was 4.4%. The overall survival (p=0.913) and valve-related event-free survival (p=0.204) did not differ between the two groups. The independent predictor of postoperative complications was New York Heart Association class (p=0.001). Multiple valve surgery was not a significant predictor of surgical mortality (p=0.225) or late mortality (p=0.936). Uncontrolled infection, urgent or emergency surgery, and postoperative complications were identified as independent predictors of valve-related morbidity, excluding multiple valve surgery (p=0.072). CONCLUSION: In native valve IE, multiple valve surgery as a factor was not an independent predictor of mortality and morbidity. The number of surgically corrected valves in native IE seems to be unrelated to perioperative and long-term outcomes.

9.
Tex Heart Inst J ; 40(3): 343-6, 2013.
Article in English | MEDLINE | ID: mdl-23914036

ABSTRACT

Rupture of an aortic arch aneurysm is a life-threatening condition that requires emergency operation. For rupture of a distal arch aneurysm, we performed--with the patient under total circulatory arrest--an emergency total arch replacement with an elephant-trunk procedure, followed by one-stage antegrade stent-grafting. Prompt institution of cardiopulmonary bypass and total circulatory arrest has the advantage of lessening the risk of overt aortic rupture in this emergency situation.


Subject(s)
Aorta, Thoracic/surgery , Aortic Aneurysm, Thoracic/surgery , Aortic Rupture/surgery , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Aged , Aorta, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Rupture/diagnostic imaging , Aortography/methods , Cardiopulmonary Bypass , Emergencies , Heart Arrest , Humans , Male , Tomography, X-Ray Computed , Treatment Outcome
10.
BMC Neurol ; 13: 46, 2013 May 21.
Article in English | MEDLINE | ID: mdl-23692963

ABSTRACT

BACKGROUND: This study attempts to explore the clinical features, possible mechanisms and prognosis of the neurologic complications in patients with acute aortic dissection (AD). METHODS: Medical records of 278 consecutive patients with AD (165 with type A and 113 with type B dissection) over 11.5 years were retrospectively analyzed for clinical history, CT findings, neurologic complications and outcome. Neurologic complications were classified into early-onset or delayed-onset complications. Independent t-test or Chi-square test (or Fisher exact test) was used for comparing the different groups. Multivariable logistic regression analysis was performed to determine the independent association between variables. RESULTS: The mean age of the included patients (145 male and 133 female) was 59.4 years (range 19-91 years). 41 patients (14.7%) had a neurologic complication, which included 21 with early-onset complication and 23 with delayed-onset complication, including 3 with both. Advanced age and classic type of dissection were independently associated with the neurologic complication in patients with type A dissection. The most frequent manifestation was ischemic stroke (26 patients, 9.4%), followed by hypoxic encephalopathy (9, 3.2%), ischemic neuropathy (5, 1.8%), spinal cord ischemia (5, 1.8%), seizure (2, 0.7%), hoarseness (1, 0.4%) and septic encephalopathy (1, 0.4%). Overall in-hospital mortality was 10.1%, whereas the complicated group had a mortality rate of 43.9%. Renal impairment, pulse deficit, neurologic complication and nonsurgical treatment were independent variables for determining in-hospital mortality in patients with type A dissection. CONCLUSIONS: The dominance of neurologic symptom in the early stage of AD may make its early diagnosis difficult. Besides chest pain and widened mediastinum in chest x-ray, variable neurologic symptoms including left hemiparesis with asymmetric pulse and hypotension may suggest underlying AD.


Subject(s)
Aortic Aneurysm , Aortic Dissection , Nervous System Diseases , Adult , Aged , Aged, 80 and over , Aortic Dissection/complications , Aortic Dissection/epidemiology , Aortic Dissection/mortality , Aortic Aneurysm/complications , Aortic Aneurysm/epidemiology , Aortic Aneurysm/mortality , Female , Humans , Male , Middle Aged , Nervous System Diseases/epidemiology , Nervous System Diseases/etiology , Nervous System Diseases/mortality , Republic of Korea/epidemiology , Retrospective Studies , Young Adult
11.
J Card Surg ; 28(3): 280-4, 2013 May.
Article in English | MEDLINE | ID: mdl-23480627

ABSTRACT

BACKGROUND AND AIM OF THE STUDY: The purpose of this study is to evaluate the long-term outcomes of the button Bentall procedure for the correction of aortic root disease. METHODS: A total of 195 patients who underwent the button Bentall procedure between 1997 and 2010 were studied. The main pathology was annuloaortic ectasia. A mechanical valve was used in 163 patients (83.6%). The median duration of follow-up was 64 months (14133.0 patient-years). RESULTS: There were five operative deaths (2.6%). Late overall mortality was 7.9%. The actuarial overall survival rate was 95.8 ± 1.5% at 5 years, 89.6 ± 3.4% at 10 years, and 75.9 ± 7.3% at 15 years. Multivariate logistic regression analysis identified preoperative poor mobility, cardiopulmonary bypass time, deep hypothermic circulatory arrest (DHCA) use, embolism, and bleeding event as significant independent risk factors for the late overall mortality. At 5, 10, and 15 years, actuarial composite valve graft-related event-free survival was 85.8 ± 2.8%, 75.5 ± 4.4%, and 69.3 ± 7.3%, respectively. Hypertension and concomitant coronary artery bypass graft (CABG) were independent predictors of composite valve graft-related events. Age, concomitant CABG, and DHCA use were associated with bleeding. CONCLUSIONS: Valve-related morbidities, such as embolism and bleeding, determine the long-term overall mortality in aortic root replacement with button Bentall operation, similar to that in routine valve surgery.


Subject(s)
Aorta/surgery , Aortic Aneurysm/surgery , Aortic Dissection/surgery , Aortic Valve/surgery , Cardiac Surgical Procedures/methods , Cause of Death , Coronary Vessels/surgery , Heart Valve Prosthesis Implantation , Marfan Syndrome/surgery , Postoperative Complications/mortality , Adult , Aged , Aorta, Thoracic/surgery , Cardiopulmonary Bypass , Female , Follow-Up Studies , Hospital Mortality , Humans , Male , Middle Aged
12.
J Card Surg ; 28(2): 102-8, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23356418

ABSTRACT

BACKGROUND: An enlarged left atrium (LA) is a major risk factor for atrial fibrillation (AF) recurrence after a maze operation. METHODS: Between 2000 and 2009, 35 patients underwent circumferential left atrium resection (CLAR), during mitral valve surgery. All patients had continuous AF. RESULTS: Hospital mortalities occurred in two patients (5.7%). Postoperative bleeding occurred in two patients (5.7%). The average follow-up was 64 months. The mean New York Heart Association (NYHA) functional class had significantly decreased to 1.16 ± 0.37 from 2.77 ± 0.65 (p < 0.01). The mean LA dimension and the cardiothoracic ratio had significantly decreased to 52.8 ± 7.9 mm, and 0.55 ± 0.06 from 72.6 ± 11.0 mm, and 0.66 ± 0.11, respectively (p < 0.01). The mean early postoperative LA volume had decreased to 178 ± 68 mL (102-343 mL) from 332 ± 133 mL (124-655 mL) (p < 0.001). These LA volume reductions had been maintained until the last echocardiogram, which was done at an average of 29 months. In patients who underwent the maze procedure, the rate of sinus rhythm restoration was 82.1%, 81.5%, and 74% at three to six months, one year, and the last visit, respectively. CONCLUSION: CLAR significantly reduced the LA volume. CLAR had an additional beneficial effect with the maze procedure of a relative rate of sinus rhythm restoration. To clarify the role of CLAR in marked symptom improvements after mitral valve surgery in patients with a giant LA, well-designed comparative studies are required.


Subject(s)
Cardiomegaly/surgery , Heart Atria/surgery , Adult , Aged , Atrial Fibrillation/etiology , Atrial Fibrillation/mortality , Atrial Fibrillation/surgery , Cardiomegaly/complications , Cardiomegaly/diagnostic imaging , Cardiomegaly/mortality , Female , Follow-Up Studies , Heart Atria/pathology , Hospital Mortality , Humans , Male , Middle Aged , Postoperative Hemorrhage/epidemiology , Retrospective Studies , Treatment Outcome , Ultrasonography
13.
Cerebrovasc Dis ; 33(5): 471-9, 2012.
Article in English | MEDLINE | ID: mdl-22517375

ABSTRACT

BACKGROUND: Cardiac myxomas are rare but are the most common cardiac tumors. This study is based on our clinical experience with cardiac myxomas over a period of 11 years at Sejong General Hospital. We focused on the embolic complications of patients with cardiac myxoma. METHODS: We retrospectively reviewed the medical records of 59 consecutive patients with cardiac myxoma who were treated between January 2000 and March 2011. The myxomas were divided into two types: type 1, with an irregular or villous surface and a soft consistency, and type 2, with a smooth surface and a compact consistency. The 59 investigated patients were classified into the embolic group and the non-embolic group. RESULTS: Cardiac obstructive symptoms, embolic events and constitutional symptoms were observed in 37 (62.7%), 13 (22.0%) and 10 (16.9%) patients, respectively. When the embolic and non-embolic groups were compared, there were no significant differences in vascular risk factors, the ejection fraction, the left atrial diameter or the tumor size. However, type 1 myxomas were significantly more frequent in the embolic group (p = 0.009 by Fisher's exact test). A binary logistic regression analysis showed that type 1 pathology alone was independently associated with myxoma-related embolism (p = 0.008; odds ratio 10.056; 95% confidence interval 1.828-55.337). There were no operative deaths in any of the 59 patients studied. Among the 13 patients with embolism, 11 (84.6%) had brain infarcts. The main patterns of the lesions were multiple lesions (8 out of 11 patients, 72.7%) and lesions in the middle cerebral artery territories (7 out of 11 patients, 63.6%). The other 2 patients were found to have occlusion of the left central retinal artery and left external iliac artery. Additionally, incidental cerebral aneurysms were found in the latter case. There was no recurrence of myxoma or myxoma-related symptoms in the 53 patients receiving outpatient management during the follow-up period (range 2 months to 11 years). CONCLUSIONS: The embolic potential of myxoma was associated with an irregular surface pathology but not with vascular risk factors. Echocardiography should be performed in patients with embolic events, especially when cerebral infarcts with multiple territorial lesions are detected. Surgical resection is a relatively safe and curative procedure for cardiac myxoma.


Subject(s)
Embolism/etiology , Heart Neoplasms/complications , Myxoma/complications , Adult , Age Factors , Aged , Arterial Occlusive Diseases/epidemiology , Arterial Occlusive Diseases/etiology , Atrial Fibrillation/complications , Atrial Fibrillation/epidemiology , Cardiac Surgical Procedures/statistics & numerical data , Cerebral Infarction/epidemiology , Cerebral Infarction/etiology , Chest Pain/epidemiology , Chest Pain/etiology , Coronary Angiography , Embolism/epidemiology , Female , Heart Neoplasms/epidemiology , Heart Neoplasms/surgery , Humans , Hypertension/complications , Hypertension/epidemiology , Male , Middle Aged , Myxoma/epidemiology , Myxoma/surgery , Regression Analysis , Republic of Korea/epidemiology , Sex Factors , Smoking/adverse effects , Smoking/epidemiology , Stroke/pathology , Tomography, X-Ray Computed , Treatment Outcome
14.
Int J Cardiovasc Imaging ; 27(5): 639-45, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21503705

ABSTRACT

The purpose of this study was to examine the incidence of pulmonary embolism (PE) after a coronary artery bypass graft (CABG) using 64-slice multidetector CT (MDCT), and to determine the correlations between the occurrence of a PE and the clinical or surgical parameters. Three hundred and twenty-six consecutive patients, who underwent coronary CT angiography using 64-slice MDCT to assess the graft patency after CABG, were enrolled in this study. Additional axial CT images, which were reconstructed by adopting a large field of view and thinner image slices, were reviewed for the presence of PE. The relationship between the occurrence of a PE and the type of surgery (off-pump CABG versus conventional CABG), number of target vessels, use of a saphenous vein graft, and length of stay in the intensive care unit (ICU) were evaluated. PE was detected on the CT images of 33 patients (10.1%), which involved the lobar or more proximal arteries in seven patients and the segmental or subsegmental arteries in 26. PE occurred more frequently after off-pump CABG (16.5%, 14/85) than after conventional CABG (7.9%, 19/241) (P = 0.024). Patients with PE were older (67 years vs. 62.7 years) and had longer stays in the ICU (5.6 days vs. 3.8 days) than those without (P = 0.013 and P = 0.007, respectively). No significant difference was observed in the number of target vessels and use of a saphenous vein graft between patients with and without an embolism. In a multi-variable analysis, the age of the patient, surgical methods, and ICU stay were independent predictors for the occurrence of PE (P = 0.013, P = 0.017, and P = 0.005, respectively). MDCT helps detect PE in patients after CABG. It is encountered more frequently after off-pump CABG than after conventional CABG and in older patients with longer ICU stays.


Subject(s)
Coronary Angiography/methods , Coronary Artery Bypass/adverse effects , Pulmonary Embolism/diagnostic imaging , Tomography, X-Ray Computed , Adult , Age Factors , Aged , Aged, 80 and over , Chi-Square Distribution , Coronary Artery Bypass, Off-Pump/adverse effects , Female , Humans , Incidence , Intensive Care Units , Length of Stay , Logistic Models , Male , Middle Aged , Predictive Value of Tests , Pulmonary Embolism/epidemiology , Pulmonary Embolism/etiology , Republic of Korea/epidemiology , Retrospective Studies , Risk Assessment , Risk Factors , Time Factors , Treatment Outcome , Vascular Patency
15.
Korean J Thorac Cardiovasc Surg ; 44(3): 236-9, 2011 Jun.
Article in English | MEDLINE | ID: mdl-22263158

ABSTRACT

Indication for extracorporeal membrane oxygenation (ECMO) has been extended as the experience of ECMO in various clinical settings accumulates and the outcome after ECMO installation improves. We report two cases of successful mitral valve surgery for severe ischemic mitral regurgitation in patients on ECMO support for cardiogenic shock which developed upon coronary angiography.

16.
J Korean Med Sci ; 24(5): 818-23, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19794977

ABSTRACT

Triple valve surgery is usually complex and carries a reported operative mortality of 13% and 10-yr survival of 61%. We examined surgical results based on our hospital's experience. A total of 160 consecutive patients underwent triple valve surgery from 1990 to 2006. The most common aortic and mitral valve disease was rheumatic disease (82%). The most common tricuspid valve disease was functional regurgitation (80%). Seventy-four percent of the patients were in New York Heart Association (NYHA) class III and IV. Univariate and multivariable analyses were performed to identify predictors of early and late survival. Operative mortality was 6.9% (n=11). Univariate factors associated with mortality included old age, preoperative renal failure, postoperative renal failure, pulmonary complications, and stroke. Of them, postoperative renal failure and stroke were associated with mortality on multivariable analysis. Otherwise, neither tricuspid valve replacement nor reoperation were statistically associated with late mortality. Survival at 5 and 10 yr was 87% and 84%, respectively. Ninety-two percent of the patients were in NYHA class I and II at their most recent follow-up. Ten-year freedom from prosthetic valve endocarditis was 97%; from anticoagulation-related hemorrhage, 82%; from thromboembolism, 89%; and from reoperation, 84%. Postoperative renal failure and stroke were significantly related with operative mortality. Triple valve surgery, regardless of reoperation and tricuspid valve replacement, results in acceptable long-term survival.


Subject(s)
Aortic Valve/surgery , Heart Valve Diseases/surgery , Heart Valve Prosthesis Implantation/methods , Mitral Valve/surgery , Tricuspid Valve/surgery , Adult , Aged , Anticoagulants/adverse effects , Anticoagulants/therapeutic use , Female , Heart Valve Diseases/complications , Heart Valve Diseases/mortality , Hemorrhage/chemically induced , Hemorrhage/epidemiology , Humans , Intraoperative Complications/mortality , Male , Middle Aged , Postoperative Complications/mortality , Renal Insufficiency/etiology , Reoperation , Risk Factors , Severity of Illness Index , Stroke/etiology , Survival Analysis , Thromboembolism/epidemiology
17.
Eur J Cardiothorac Surg ; 36(6): 1006-10, 2009 Dec.
Article in English | MEDLINE | ID: mdl-19643622

ABSTRACT

BACKGROUND: We evaluated the efficacy of a well-prepared left internal thoracic artery (LITA) auto Y graft for simultaneous left anterior descending artery (LAD) and diagonal artery (DA) re-vascularisation in selected patients for the reduction of the number of required grafts and improved graft patency, while limiting technical problems. METHODS: Twenty well-controlled diabetic patients, mean age 62.8+/-8.3, 17 males and three females, underwent isolated elective off-pump coronary artery bypass grafting using the LITA auto Y graft from July 2003 to August 2004. RESULTS: In-hospital data and angiographic results at 6 months after the surgery showed that there was no early mortality, early graft failure and major morbidity except for two cases of superficial wound infection. The 3-year follow-up results including angiographic findings (mean of 37+/-3.3-month follow-up) demonstrated that all patients are alive and have excellent graft patency in both the LAD and DA. Only two cases required right coronary artery (RCA) stenting during the follow-up period. Compared with our previous routine LITA composite Y graft technique, it is assumed that LITA auto Y graft technique may reduce the number of mobilised conduits or avoided sequential anastomosis. CONCLUSIONS: This small study showed that our technique is technically feasible and may be safely performed to the selective patients. The LITA auto Y graft might be an additional surgical option, in terms of not only preserving the other grafts and maintaining patency in the LAD area bypass, but also preventing the need for sequential anastomoses.


Subject(s)
Coronary Artery Bypass, Off-Pump/methods , Internal Mammary-Coronary Artery Anastomosis/methods , Aged , Coronary Angiography , Coronary Stenosis/surgery , Diabetic Angiopathies/surgery , Female , Follow-Up Studies , Humans , Male , Middle Aged , Treatment Outcome , Vascular Patency
18.
Eur J Cardiothorac Surg ; 33(3): 341-8, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18255308

ABSTRACT

OBJECTIVE: Radial arteries are gaining widespread acceptance as complementary arterial conduits for surgical myocardial revascularization, but there are limited reports about its angiographic patency compared with that of the internal thoracic artery or saphenous vein according to the degree of native coronary stenosis. Therefore, we tried to evaluate the mid-term angiographic results of the radial artery graft patency focusing on the native coronary stenotic status in a prospective manner. METHODS: From March 2000 to September 2006, a total of 488 patients underwent coronary artery bypass grafting using radial artery graft at our institution. From this group, 123 patients (mean age of 59.02+/-8.9 years (range 34-73 years)) were enrolled in the present study, and underwent a postoperative angiography after surgery (mean 32 months). The angiograms were assessed visually and quantitatively. RESULTS: A total of 382 distal anastomoses were performed and 352 anastomosis remained patent (92.1%). Left internal thoracic artery showed the most excellent patency in all of the conduits (128/129, 99.2%). Overall the radial artery graft patency was 92% (160/174). In the univariate analysis, patency was significantly worse for targets of the right coronary system (left coronary system 129/135, 94.4% vs right coronary system 31/39, 79.4%. p<0.05) and the radial artery graft showed a higher patency rate in the case of a severe stenotic lesion that preoperatively revealed more than 90% stenosis (defined as critical stenotic lesion) than in the case of a less severe lesion (50%

Subject(s)
Coronary Artery Bypass/methods , Coronary Disease/surgery , Coronary Stenosis/diagnostic imaging , Mammary Arteries/surgery , Radial Artery/transplantation , Vascular Patency , Adult , Aged , Coronary Angiography , Coronary Disease/diagnostic imaging , Female , Humans , Male , Mammary Arteries/diagnostic imaging , Middle Aged , Prospective Studies , Treatment Outcome
19.
Interact Cardiovasc Thorac Surg ; 4(2): 130-4, 2005 Apr.
Article in English | MEDLINE | ID: mdl-17670373

ABSTRACT

This study evaluated the mid-term results of the modified maze procedure using cryoablation for treating atrial fibrillation associated with rheumatic mitral valve disease. Between March 2000 and February 2004, 177 consecutive patients underwent the modified maze procedure using cryoablation concomitant with mitral valve surgery, were divided into the modified Cox-Maze III (group CM, n=88), modified Kosakai-Maze (group KM, n=63) and left atrial maze (group LA, n=26) procedures. Postoperative and follow-up results were analyzed and compared between the groups, with a mean follow-up time of 22.4+/-15.1 months. There were three hospital deaths (1.7%). The operative time was significantly longer in the group CM than the KM or LA groups, respectively. One late death developed in the CM group. At last follow-up, 139 patients had sinus rhythm (79.9%), which was regained in 67 CM (77.9%), 50 KM (80.7%) and 22 (84.6%) LA group (P=0.743) patients. Freedom from stroke at 4 years was 84.6% in the CM, 95.0% in the KM, and 92.9% in the LA (P=0.916) groups. There were no significant differences in the sinus conversion or stroke rate between patients with the left atrial appendage preserved and those with it excised or obliterated. The modified maze procedure using cryoablation is safe and effective, with an acceptable sinus conversion rate and clinical improvement.

20.
Ann Thorac Surg ; 78(3): 1081-2, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15337057

ABSTRACT

We present the case of a Cabrol-type proximal anastomosis technique in off-pump coronary artery bypass. The patient was a 64-year-old man with significant stenoses on the left main, left anterior descending, and proximal right coronary artery. The obtuse marginal and right coronary arteries were anastomosed with both ends of a radial artery. For the proximal anastomosis during this procedure, we applied the Cabrol-type looping interposition technique. In selected patients, we suggest that this technique allows the effective use of graft length and can reduce a number of ascending aortic manipulations.


Subject(s)
Coronary Artery Bypass/methods , Coronary Disease/surgery , Radial Artery/transplantation , Anastomosis, Surgical/methods , Angina, Unstable/etiology , Coronary Angiography , Coronary Disease/complications , Coronary Disease/diagnostic imaging , Follow-Up Studies , Humans , Male , Middle Aged
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