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2.
ACS Appl Mater Interfaces ; 12(1): 1698-1706, 2020 Jan 08.
Article in English | MEDLINE | ID: mdl-31825585

ABSTRACT

Wearable pressure sensors have been attracting great attention for a variety of practical applications, including electronic skin, smart textiles, and healthcare devices. However, it is still challenging to realize wearable pressure sensors with sufficient sensitivity and low hysteresis under small mechanical stimuli. Herein, we introduce simple, cost-effective, and sensitive capacitive pressure sensor based on porous Ecoflex-multiwalled carbon nanotube composite (PEMC) structures, which leads to enhancing the sensitivity (6.42 and 1.72 kPa-1 in a range of 0-2 and 2-10 kPa, respectively) due to a synergetic effect of the porous elastomer and percolation of carbon nanotube fillers. The PEMC structure shows excellent mechanical deformability and compliance for an effective integration with practical wearable devices. Also, the PEMC-based pressure sensor shows not only the long-term stability, low-hysteresis, and fast response under dynamic loading but also the high robustness against temperature and humidity changes. Finally, we demonstrate a prosthetic robot finger integrated with a PEMC-based pressure sensor and an actuator as well as a healthcare wristband capable of continuously monitoring blood pressure and heart rate.


Subject(s)
Biosensing Techniques , Blood Pressure Determination/instrumentation , Monitoring, Physiologic , Nanotubes, Carbon/chemistry , Elastomers/chemistry , Humans , Mechanical Phenomena , Porosity , Textiles , Wearable Electronic Devices
3.
Adv Healthc Mater ; 8(22): e1900978, 2019 11.
Article in English | MEDLINE | ID: mdl-31596545

ABSTRACT

Wearable pressure sensors capable of sensitive, precise, and continuous measurement of physiological and physical signals have great potential for the monitoring of health status and the early diagnosis of diseases. This work introduces a 3D-printed rigid microbump-integrated liquid metal-based soft pressure sensor (3D-BLiPS) for wearable and health-monitoring applications. Using a 3D-printed master mold based on multimaterial fused deposition modeling, the fabrication of a liquid metal microchannel and the integration of a rigid microbump array above the microchannel are achieved in a one-step, direct process. The microbump array enhances the sensitivity of the pressure sensor (0.158 kPa-1 ) by locally concentrating the deformation of the microchannel with negligible hysteresis and a stable signal response under cyclic loading. The 3D-BLiPS also demonstrates excellent robustness to 10 000 cycles of multidirectional stretching/bending, changes in temperature, and immersion in water. Finally, these characteristics are suitable for a wide range of applications in health monitoring systems, including a wristband for the continuous monitoring of the epidermal pulse rate for cuffless blood pressure estimation and a wireless wearable device for the monitoring of body pressure using a multiple pressure sensor array for the prevention of pressure ulcers.


Subject(s)
Printing, Three-Dimensional , Wearable Electronic Devices , Pressure , Temperature , Wireless Technology
4.
Korean J Intern Med ; 20(2): 141-5, 2005 Jun.
Article in English | MEDLINE | ID: mdl-16134769

ABSTRACT

BACKGROUND: Hypertension is an important risk factor for sudden cardiac death, of which the incidence increases with increases in blood pressure. Prolonged QT dispersion has been identified to indicate increased risk of life-threatening ventricular arrhythmia and sudden cardiac death. In this study, QT dispersion was investigated in hypertensive patients during the strain phase of the Valsalva maneuver. METHODS: The study population included 75 subjects: 25 with normal blood pressure (Control), 25 with stage I hypertension (Group A), and 25 with stage II hypertension (Group B). Electrocardiography for QT dispersion was recorded at 25 mm/sec paper speeds before and during the Valsalva maneuver. RESULTS: The patients in Group B were significantly older than the controls (p<0.05). Differences in sex, smoking, diabetes, angina, and hyperlipidemia were not statistically significant between the three groups. The basal QT dispersion was 25.3 +/- 18.3 ms in the controls, 39.0 +/- 17.8 ms in Group A, and 36.8 +/- 18.8 ms in Group B. The QT dispersion was significantly higher in group A patients than the controls (p<0.05). In Group B only, a significant increase in QT dispersion was observed during the Valsalva maneuver, compared to conditions prior to the Valsalva maneuver (p<0.05). CONCLUSION: The conditions that increase intrathoracic pressure may increase QT dispersion and severe hypertensive patients should avoid these conditions.


Subject(s)
Electrocardiography , Hypertension/physiopathology , Valsalva Maneuver/physiology , Blood Pressure/physiology , Female , Humans , Hypertension/diagnosis , Male , Middle Aged , Retrospective Studies , Risk Factors
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