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Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis.
Mazereeuw-Hautier, Juliette; Hoeger, Peter H; Benlahrech, Sarah; Ammour, Amir; Broue, Pierre; Vial, Julie; Ohanessian, Gerard; Léauté-Labrèze, Christine; Labenne, Marc; Vabres, Pierre; Rössler, Jochen; Bodemer, Christine.
J Pediatr ; 157(2): 340-2, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20488455

ABSTRACT

We report the rapid and dramatic efficacy of propranolol in 8 infants with infantile hepatic hemangiomas. The degree of response varied from a significant improvement to a complete resolution of hepatic lesions. Heart failure and hypothyroidism resolved, and hepatomegaly decreased. No side-effects of the drug were noted.


Subject(s)
Hemangioma/drug therapy , Liver Neoplasms/drug therapy , Propranolol/therapeutic use , Skin Neoplasms/drug therapy , Adrenal Cortex Hormones/therapeutic use , Female , Heart Failure/prevention & control , Humans , Infant , Male , Propranolol/pharmacology , Treatment Outcome , Vasodilator Agents/therapeutic use
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