[The prevention and treatment of nausea and vomiting during cancer chemotherapy]. / Profilaktyka ta likuvannia nudoty i bliuvannia pry khimioterapiï raku.

From the point of view of patients nausea and vomiting is a very important side effect of chemotherapy. The above events can be successfully controlled with modern antiemetic therapy. Use of high doses of metoclopramide in combination with dexamethasone and lorazepame is one of the routine means of administration of chemotherapeutic treatments with the benefit being derived in 30 to 70% of patients. Introduction into the clinical practice of a new group of medicines such as antagonists of receptors to serotonin (5-HT3-blockers) opens up good prospects for the nausea and vomiting prophylaxis and treatment in chemotherapy of cancer.