ABSTRACT
PURPOSE: To investigate complications in the posterior segment after transscleral suturing of the posterior chamber in intraocular lens (PC-IOL) implantation. METHODS: Preoperative clinical characteristics and clinical course were analyzed in 13 eyes of 13 patients who underwent vitreous surgery for either suprachoroidal hemorrhage or rhegmatogenous retinal detachment after transscleral suturing in PC-IOL implantation. RESULTS: Preoperative low intraocular pressure (IOP) was found in 3 of 6 eyes with suprachoroidal hemorrhage (50%) and longer axial length in 3 eyes (50%). Retinal reattachment was achieved in 4 eyes (67%) and final vision was more than 0.1 in 3 eyes (50%). In 7 eyes of retinal detachment, retinal tear was undetected preoperatively in 3 eyes (43%), and retinal breaks were located in the superior quadrant in 5 eyes (71%), similar to the characteristics of aphakic retinal detachment. The retina was reattached in all eyes and vision improved to more than 2 Snellen lines in 6 eyes(86%). CONCLUSION: Low IOP caused by leakage from the scleral wound was a potential risk for developing suprachoroidal hemorrhage after transscleral suturing in PC-IOL implantation. A complete closure of the wounds may prevent suprachoroidal hemorrhage. Collapse and incarceration of the peripheral vitreous may cause retinal detachment and complete removal of the peripheral vitreous may prevent retinal detachment.
Subject(s)
Choroid Hemorrhage/etiology , Lens Implantation, Intraocular/adverse effects , Postoperative Complications/etiology , Retinal Detachment/etiology , Sutures/adverse effects , Aged , Aged, 80 and over , Choroid Hemorrhage/pathology , Female , Humans , Male , Middle Aged , Retinal Detachment/pathology , Sclera/surgeryABSTRACT
AIM: To evaluate the influence of topically administered latanoprost, a prostaglandin F(2alpha) analog, on the corneal epithelial barrier function. PATIENTS AND METHODS: Twenty-four patients suffering from a glaucoma were enrolled. Ten patients without prior topical antiglaucoma medication received topical latanoprost (0.005%, once daily) for 30 days (monotherapy group); 14 patients receiving topical antiglaucoma medication also received latanoprost (0.005%, once daily) for 180 days (combination treatment group). Before and 30 days after treatment (monotherapy group) and before and 30 and 180 days after treatment (combination group), the corneal epithelial barrier function was measured by a fluorophotometric technique. RESULTS: The fluorescein uptakes in the monotherapy group were 54.6 +/- (SE) 7.5 and 57.1 +/- 11.0 ng/ml before and 30 days after treatment, respectively (p = 0.81). In the combination group, the uptakes were 101.0 +/- 18.3 and 118.9 +/- 25.9 ng/ml (p = 0.38) and 93.4 +/- 17.5 ng/ml (p = 0.58) before and 30 and 180 days after treatment, respectively. CONCLUSION: The corneal epithelial barrier function remained intact following the instillation of latanoprost in both groups.
