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1.
Eur Rev Med Pharmacol Sci ; 26(23): 9021-9029, 2022 12.
Article in English | MEDLINE | ID: mdl-36524521

ABSTRACT

OBJECTIVE: This study aimed to assess the prevalence, risk factors, culture results, clinical features, visual outcomes, and therapeutic strategies of infectious keratitis after surface ablation (PRK). PATIENTS AND METHODS: This single-center prospective case-series review comprised 6500 eyes of 3400 patients undergoing PRK operation successively at the Ardabil Noor Surgical Center between January 1, 2003, and February 1, 2020. The incidence, risk factors, and clinical course were recorded for these samples. RESULTS: Three clinical and culture-proven cases of infectious keratitis in three eyes of three patients were diagnosed during the study period. Post-operative keratitis was observed in cases 1 and 2 after 3 days and in case 3 after 112 days. The results of cultures were positive in all three cases. The isolated microorganisms were Staphylococcus species in cases 1 and 2 and Candida Albicans in case 3. The final corrected distance visual acuity was 20/25 and 20/20 in cases 1 and 2, respectively, and hand motion in case 3. All three patients had some risk factors such as well-controlled familial Mediterranean fever, mild Meibomian gland dysfunction, and the healthcare environment of the patient's wife in case 1, contact lens manipulation in case 2, and dry eye in case 3. CONCLUSIONS: The prevalence of infectious keratitis after PRK was 0.046%. Infectious keratitis is one of the complications of PRK that can threaten patients' vision. Accordingly, proper preoperative clinical history taking, adequate eye exam and aggressive management can help maintain good eyesight in patients who undergo PRK surgery.


Subject(s)
Eye Infections, Bacterial , Keratitis , Humans , Prevalence , Retrospective Studies , Keratitis/epidemiology , Risk Factors , Anti-Bacterial Agents/therapeutic use
2.
Vaccine ; 22(25-26): 3240-2, 2004 Sep 03.
Article in English | MEDLINE | ID: mdl-15308345

ABSTRACT

During the largest mass campaign for measles-rubella (MR) vaccination 33,000,000 people with an age range of 5-25 years were vaccinated in Iran. Some complications were encountered, including a rare case of optic neuritis. In the past 30 years of medical literature, five cases of optic neuritis have been reported but all of them were developed at least 8 days after vaccination. We are supposed to report the first case of rapid onset optic neuritis in which the complication came out just in few hours in a 16 years old boy.


Subject(s)
Measles Vaccine/adverse effects , Optic Neuritis/etiology , Rubella Vaccine/adverse effects , Adolescent , Humans , Male , Measles Vaccine/immunology , Neuralgia/diagnosis , Neuralgia/etiology , Rheumatic Diseases/diagnosis , Rheumatic Diseases/etiology , Rubella Vaccine/immunology , Vaccines, Combined/adverse effects , Vaccines, Combined/immunology , Vision Disorders/diagnosis , Vision Disorders/etiology , Visual Acuity/physiology
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