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1.
J Vasc Surg ; 47(5): 1099-107, 2008 May.
Article in English | MEDLINE | ID: mdl-18242942

ABSTRACT

OBJECTIVE: This study was conducted to determine the efficacy and safety of stent grafts in the treatment of thoracic aortic aneurysms and dissections. METHOD: Our health technology assessment method combined a critical review of the literature with experts' opinions. Several databases, useful Web sites, and the gray literature were searched from January 1995 to December 2004. Some manually retrieved major articles published in 2005 were also included. The draft report was submitted to and discussed by a working group of 12 members nominated by relevant medical societies. The amended report was submitted to a multidisciplinary group of 12 peer reviewers for comment. RESULTS: Endovascular stent grafting (ESG) repair for lesions of the thoracic aorta, including aneurysms, dissections, and aortic isthmus ruptures, is probably beneficial in terms of operative mortality and severe morbidity, with an incidence of paraplegia of 2.1% (range 0%-7%) for ESG vs 5% (range, 3%-15%) for surgery, provided that there is a rigorous medium-term assessment and that anatomic factors are favorable. A proximal neck length of at least 2 cm is needed to insert the stent graft. Indications for ESG in thoracic aortic aneurysm and dissection are similar to those for surgery. Endovascular stent grafting is particularly appropriate in patients with multiple traumas to the thoracic aorta in whom concomitant lesions are a contraindication to open surgery. Endovascular stent graft repair can only be done in public or private centers with expertise in both endovascular and surgical procedures and with adequate technical facilities. Patients should be informed of the advantages and drawbacks of both methods. A multidisciplinary discussion should address risks of converting to open surgery and possible need for a cardiopulmonary bypass. Patients should be monitored annually by computed tomography scan or magnetic resonance imaging and plain radiographs because long-term results are uncertain (possible stent graft deterioration, onset of aortic disease). They should be told of the need for surveillance and possible further treatment. CONCLUSIONS: A prospective registry of all thoracic aorta procedures (endovascular treatment, open surgery, thoracic ESG plus extra-anatomic bypass) needs to be set up. All practitioners and stent graft manufacturers should contribute to this registry. It should include information on patient monitoring in order to (1) select patients who could be treated by ESG repair, (2) assess the feasibility of a randomized controlled study comparing ESG and surgery, (3) assess the medium-term outcome of different devices, and (4) obtain a better understanding of the health economics aspects.


Subject(s)
Aortic Aneurysm, Thoracic/surgery , Aortic Dissection/surgery , Blood Vessel Prosthesis Implantation/instrumentation , Blood Vessel Prosthesis , National Health Programs , Stents , Aortic Dissection/mortality , Aortic Dissection/pathology , Aortic Aneurysm, Thoracic/mortality , Aortic Aneurysm, Thoracic/pathology , Blood Vessel Prosthesis Implantation/adverse effects , France , Humans , Paraplegia/etiology , Patient Selection , Practice Guidelines as Topic , Prosthesis Failure , Registries , Risk Assessment , Treatment Outcome
2.
Presse Med ; 31(17): 775-81, 2002 May 11.
Article in French | MEDLINE | ID: mdl-12148359

ABSTRACT

THE IMPACT FACTOR OF MEDICAL JOURNALS: Is a criterion for the assessment of their activity. Three bibliometrical indicators are published every year: the impact factor, the rapidity of citation index, which reflects the upward slope in increased citations and the duration of their actuality, reflecting the downward slope, after the peak. THE JOURNALS USED TO CALCULATE THESE INDICATORS: Are selected according to their periodicity, conformity to international editorial conventions, presence of a reading committee, of their citation frequency and, for a new journal, the earlier publications of the redaction committee and the authors. THERE ARE SEVERAL BIASES IN THE CALCULATION OF THE IMPACT FACTOR: The choice of the citations is subjective and the non-pertinence of the citations is well known. Several variables may intervene, such as the type of journal and its size, domain concerned, language of the publication, self-citations, coding of the articles depending on their nature, and the choice of the manuscripts published ("hot papers"). The impact factor is an indicator of citations and not of their quality, and can certainly not be used to assess an authors' work.


Subject(s)
Periodicals as Topic/trends , Bibliometrics , France , Language , Periodicals as Topic/standards , Publishing/trends , Reading
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