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1.
Clin J Gastroenterol ; 6(2): 169-72, 2013 Apr.
Article in English | MEDLINE | ID: mdl-26181457

ABSTRACT

Visceral artery aneurysms are rare, with an incidence rate of only 0.01-0.2 % in routine autopsies, and hepatic artery aneurysms account for approximately 20 % of these aneurysms. Despite recent advances in therapeutic techniques and diagnostic tools, the management of visceral artery aneurysms remains clinically challenging. We report a case of hepatic artery aneurysm with liver cirrhosis due to hepatitis C in an 81-year-old woman. A computed tomography scan demonstrated a hepatic artery aneurysm 4.4 cm in diameter. She underwent successful aneurysmectomy with vascular anastomosis. A computed tomography scan on postoperative day 7 demonstrated patent hepatic artery. The patient was followed-up for 1 year after surgery and died owing to progressive liver failure. However, she did not show any hepatic artery problem such as hepatic arterial thrombosis or occlusion. We discuss the risk factors of atherosclerosis in patients with liver cirrhosis, and present an overview of the treatment of hepatic artery aneurysms.

3.
Fukuoka Igaku Zasshi ; 104(12): 539-48, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24693682

ABSTRACT

INTRODUCTION: Surgery remains the treatment of choice for patients with resectable biliary tract cancer, enhancing the chance of cure and increasing long-term survival. Early recurrence, however, is frequent in patients who have undergone curative resection. To date, no randomized controlled trials have assessed adjuvant chemotherapy in patients with biliary tract cancer. The aim of this study was to evaluate the outcomes of surgical management followed by adjuvant chemotherapy in patients with biliary tract cancer. MATERIALS AND METHODS: This study enrolled 100 patients with Union for International Cancer Control (UICC) stages I-IV biliary tract cancer who underwent surgical resection, including 16 who received sequential adjuvant chemotherapy with gemcitabine or S-1. Overall survival (OS), disease-free survival (DFS), and prognostic factors were analyzed. RESULTS: The median duration of follow-up was 12.6 months. Forty-one patients had lymph node metastasis and 81 underwent RO resection. The 1-, 3-, and 5-year OS rates were 80.9%, 48.6%, and 38.3%, respectively, and the 1-, 3-, and 5-year DFS rates were 59.8%, 39.9%, and 24.9%, respectively. Five-year OS rates were similar in patients who did (40.4%) and did not (32.4%) receive adjuvant chemotherapy. The morbidity and mortality rates were 59% and 3%, respectively. Multivariate analysis showed that only lymph node metastasis (p = 0.042) was independently associated with long-term survival. CONCLUSIONS: The presence of lymph node metastasis significantly affected long-term survival, whereas adjuvant chemotherapy did not affect outcomes in our patients with resectable biliary tract cancer.


Subject(s)
Antimetabolites, Antineoplastic/administration & dosage , Biliary Tract Neoplasms/drug therapy , Biliary Tract Neoplasms/surgery , Biliary Tract Surgical Procedures , Deoxycytidine/analogs & derivatives , Oxonic Acid/administration & dosage , Tegafur/administration & dosage , Adult , Aged , Aged, 80 and over , Biliary Tract Neoplasms/mortality , Biliary Tract Neoplasms/pathology , Chemotherapy, Adjuvant , Deoxycytidine/administration & dosage , Disease-Free Survival , Drug Combinations , Female , Humans , Lymphatic Metastasis , Male , Middle Aged , Multivariate Analysis , Time Factors , Treatment Outcome , Gemcitabine
4.
Fukuoka Igaku Zasshi ; 103(11): 226-32, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23397877

ABSTRACT

PURPOSE: Laparoscopic hepatic resection (LHR) is still a challenging and developing surgical modality because of technical difficulty and a lack of training opportunities and experience. In this study, we present the results of our initial experiences of LHR, focusing on technical evolution in the management of LHR. METHODS: Between April 2011 and March 2012, a total of 12 LHRs were performed. The first 5 of these LHRs were performed under laparoscopic assistance (hybrid-LHR), while the last 7 LHRs were performed totally laparoscopically (pure-LHR). Indications for LHR were hepatocellular carcinoma (n = 9) and metastatic liver cancer (n = 3). LHR procedures consisted of partial resection (n = 2), left lateral segmentectomy (n = 2), and left lobectomy (n = 1) in the hybrid-LHR group, and partial resection (n = 4), left lateral segmentectomy (n = 2), and right lobectomy (n = 1) in the pure-LHR group. Operative outcomes were compared between the groups and technical modifications were evaluated. RESULTS: The mean operative time, blood loss, and length of hospital stay in the hybrid- and pure-LHR groups were 3.8 and 6.1 hours, 220 and 611 ml, and 9.4 and 7.4 days, respectively. There were no postoperative complications in both groups. Tumor margins were negative in all cases. CONCLUSIONS: LHR is a feasible and effective procedure for patients with various types of liver tumors, although technical challenges still need to be overcome.


Subject(s)
Hepatectomy/methods , Laparoscopy , Aged , Aged, 80 and over , Carcinoma, Hepatocellular/surgery , Female , Humans , Liver Neoplasms/surgery , Male , Middle Aged
5.
Case Rep Gastroenterol ; 5(2): 487-91, 2011 May.
Article in English | MEDLINE | ID: mdl-21960953

ABSTRACT

Although endoscopic retrograde cholangiopancreatography (ERCP) is an effective modality for the diagnosis and treatment of biliary and pancreatic diseases, it is still related with several severe complications. We report on the case of a female patient who developed liver parenchyma perforation following ERCP. She underwent ERCP with sphincterotomy and extraction of a common bile duct stone. Shortly after ERCP, abdominal distension was identified. Abdominal computed tomography revealed intraabdominal air leakage and leakage of contrast dye penetrating the liver parenchyma into the space around the spleen. Since periampullary perforation related to sphincterotomy could not be denied, she was referred for immediate surgery. Obvious perforation could not be found at surgery. Cholecystectomy, insertion of a T tube into the common bile duct, placement of a duodenostomy tube and drainage of the retroperitoneum were performed. She did well postoperatively and was discharged home on postoperative day 28. In conclusion, as it is well recognized that perforation is one of the most serious complication related to ERCP, liver parenchyma perforation should be suspected as a cause.

6.
Surg Today ; 39(12): 1064-7, 2009.
Article in English | MEDLINE | ID: mdl-19997802

ABSTRACT

Extraskeletal osteosarcoma is an uncommon malignant neoplasm. The origin of osteosarcoma in the pleura is extremely rare, with only four such cases so far documented in the literature to the best of our knowledge. We herein report the case of a 64-year-old Japanese man in whom a left pneumonectomy and pleurectomy were carried out to remove a huge tumor. The pathological examination confirmed a diagnosis of chondroblastic osteosarcoma that had originally arisen from the pleura.


Subject(s)
Osteosarcoma/pathology , Osteosarcoma/therapy , Pleural Neoplasms/pathology , Pleural Neoplasms/therapy , Pneumonectomy/methods , Biopsy, Needle , Chondroblastoma/pathology , Follow-Up Studies , Humans , Immunohistochemistry , Male , Middle Aged , Osteosarcoma/diagnosis , Pleural Neoplasms/diagnosis , Radiography, Thoracic , Radiotherapy, Adjuvant , Rare Diseases , Risk Assessment , Thoracoscopy/methods , Tomography, X-Ray Computed , Treatment Outcome
7.
Ann Vasc Dis ; 2(3): 174-7, 2009.
Article in English | MEDLINE | ID: mdl-23555377

ABSTRACT

We report a case of atypical aortic coarctation with severe calcification of the proximal aorta treated by a new extra-anatomical bypass. This 58-year-old woman with coarctation of the infrarenal aorta had thick circular calcifications of the thoracic aorta and stenosis of the subclavian arteries. To control the progressive claudication, we performed a bypass with an externally supported PTFE graft 6mm in diameter between the right renal artery and the right common iliac artery. Postoperative ankle pressure rose to 84 mmHg (right) and 89 mmHg (left) from zero, and she could walk without pain. Renal function was preserved. Using the proximal anastomosis from the non-diseased aortic branch to avoid the calcified aorta, reno-iliac arterial bypass is a useful alternative for control of ischemic lower limbs.

8.
Surg Today ; 38(1): 72-5, 2008.
Article in English | MEDLINE | ID: mdl-18085370

ABSTRACT

Recent advances in imaging techniques such as dynamic intravenous contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) have enabled us to detect pancreatic cysts, some of which are potentially malignant. As the histopathological diagnosis cannot be confirmed preoperatively, enlarged pancreatic cysts are usually removed surgically. We report a rare case of pancreatic angiomatosis in a 21-year-old woman who presented with vague abdominal pain, a feeling of fullness, and nausea. Abdominal ultrasonography, contrast-enhanced CT, and MRI showed a huge mass in the right upper abdomen. We performed pylorus-preserving pancreato-duodenectomy, and the histopathological examination of the excised specimen revealed that the tumor was angiomatosis, probably originating from parapancreatic fibro-adipose tissue. She is doing well and has no evidence of recurrence 8 years after the operation. A complete surgical excision should be performed as curative treatment for pancreatic angiomatosis, which is an extremely rare disease when not associated with Von Hippel-Lindau syndrome.


Subject(s)
Angiomatosis/diagnosis , Pancreatic Diseases/diagnosis , Adult , Angiomatosis/surgery , Diagnosis, Differential , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Pancreatectomy/methods , Pancreatic Diseases/surgery , Tomography, X-Ray Computed
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