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Ter Arkh ; 87(11): 99-102, 2015.
Article in Russian | MEDLINE | ID: mdl-26821425

ABSTRACT

Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.


Subject(s)
Antifungal Agents/therapeutic use , Hyponatremia , Leukemia, Lymphocytic, Chronic, B-Cell , Meningitis, Cryptococcal/drug therapy , Aged , Amphotericin B/therapeutic use , Comorbidity , Fluconazole/therapeutic use , Humans , Hyponatremia/epidemiology , Leukemia, Lymphocytic, Chronic, B-Cell/epidemiology , Male , Meningitis, Cryptococcal/epidemiology , Syndrome
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