[Biomedical research on a concentrate of carotenoids made from the North Atlantic sea cucumber Cucumaria frondosa]. / Mediko-biologicheskie issledovaniia kontsentrata karotinoidov iz severoatlanticheskogo morskogo ogurtsa Cucumaria frondosa.

Possibility of utilizing a carotenoid concentrate (CC) extracted from Cucumaria frondosa of the North Atlantic in foodstuffs and medicinal and prophylactic diet is considered. A complex of experimental studies including physiological, biochemical and morphological examinations has found that addition of CC in physiological doses to a diet of warm-blooded animals during 12 months causes no side effects. Utilization of CC in medicinal and prophylactic dietary nutrition may be beneficial.

[Hygienic substantiation of using new antibiotic preparations, tylosin phosphate and vitagrin as food additives]. / Gigienicheskoe obosnovanie primeneniia v kachestve kormovykh dobavok novykh antibioticheskikh preparatov--tilozon-fosfata i vitagrina.

Hygienic regulation of the use of the agents studied in animal experiments as food additives has been validated with respect to the dose level, regimen of addition and the period of waiting for slaughter. It is recommended that tylosin-phosphate should be included into the animals' ration as a food additive in a dose of 60 mg/kg for a short time (2-3 days), the period of waiting for slaughter being not less than 6-7 days. Addition of vitagrin has been recommended for young growing animals in a dose of 400-500 g/ton of feed. The dose of vitagrin should be reduced to 200-300 g/ton of feed one-two months before slaughter, with a 10-day period of waiting for slaughter.

[Experimental study of the possible use of sodium dehydroacetate as a food additive]. / Eksperimental'noe izuchenie vozmozhnosti ispol'zovaniia natrievoi soli degidratsetovoi kisloty v kachestve pishchevoi dobavki.

The results are presented of toxico-hygienic investigations of dehydroacetic acid sodium salt (DHASS) proposed as a food additive. The compound toxicity values have been assessed, and late results of the preservative influence on the body of experimental animals after its oral intake have been studied. An approximate value of daily intake (AVDI) of the compound has been calculated. It has been shown that DHASS cannot be recommended as a food additive because its technologically effective concentrations are significantly higher than AVDI.