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Malawi Med J ; 30(4): 298-301, 2018 Dec.
Article in English | MEDLINE | ID: mdl-31798811

ABSTRACT

Acute Megakaryoblastic Leukaemia (AML, M7) is a rare type of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts. It accounted for 1.2% of newly diagnosed AML according to Eastern Cooperative Oncology Group (ECOG) trials between 1984 and 1997. Patients may present with a broad variety of symptoms including low-grade fever, easy bruising, and life-threatening conditions. We report a rare case of AML, M7 in a 19-year-old lady who presented with weakness and fatigue. She was diagnosed as a case of AML, M7 on the basis of peripheral blood finding, bone marrow examination report, radiological findings and immunophenotyping.


Subject(s)
Leukemia, Megakaryoblastic, Acute/diagnosis , Anemia/diagnosis , Anemia/therapy , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Antibiotics, Antineoplastic/therapeutic use , Blood Transfusion , Cytarabine/therapeutic use , Daunorubicin/therapeutic use , Fatigue/etiology , Female , Humans , Immunophenotyping , Leukemia, Megakaryoblastic, Acute/drug therapy , Leukemia, Megakaryoblastic, Acute/immunology , Leukemia, Megakaryoblastic, Acute/pathology , Lost to Follow-Up , Muscle Weakness/etiology , Thrombocytopenia/diagnosis , Thrombocytopenia/therapy , Young Adult
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