1.
Pol Merkur Lekarski
; 28(168): 470-2, 2010 Jun.
Article
in Polish
| MEDLINE
| ID: mdl-20642107
ABSTRACT
Growth differentiation factor-15 (GDF-15) is a cytokine with cardioprotective properties, which inhibits hypertrophy, cardiac remodeling and apoptosis. Participates in the life and cell death. The concentration of GDF-15 rapidly increases under the influence of ischemia-reperfusion damage to heart muscle, oxidative stress, inflammatory cytokines and pressure overload. In patients with acute coronary syndromes, heart failure and pulmonary embolism provides independent prognostic information, both short-and long-term. It is potentially a new marker of risk stratification in patients with heart disease and therapeutic decision making.
Subject(s)
Growth Differentiation Factor 15/metabolism , Heart Diseases/metabolism , Biomarkers/metabolism , Heart Diseases/diagnosis , Humans , Risk Assessment/methods
2.
Kardiol Pol
; 68(1): 108-10; discussion 111, 2010 Jan.
Article
in Polish
| MEDLINE
| ID: mdl-20131199