RELATIONSHIP OF DERMATOGLYPHICS WITH SPEED OF REACTION AND TYPE OF TEMPERAMENT OF ATHLETICS.

OBJECTIVE: The aim: To establish and practically substantiate the relationship between dermatoglyphic markers and the speed of reaction and type of temperament of track and field athletes. PATIENTS AND METHODS: Materials and methods: Analysis of scientific and methodological literature, survey, dermatoglyphics, methods of mathematical and statistical processing of the received data. RESULTS: Results: Track and field athletes among the population of the Sumy region of Ukraine have a tendency to decrease the number of whorls (p<0.05). Athletes of the sanguine type of temperament are most common (67,6%), and in the control group (among students of a medical university) the phlegmatic type of temperament is most common (68,4%). Also, among the subjects of the main group there is no such temperament as melancholic. We also determined the ATD angle for the palm. It was 37±4.88 in the main group, and 47±3.11 in the control group. This indicates a hereditary predisposition of this trait. The delta index in the control group has lower values (DI=9.5) than in the main group (DI=13.3). CONCLUSION: Conclusions: We established and practically substantiated the relationship between dermatoglyphic markers and reaction speed and temperament type of track and field athletes. Determined the relationship between the anatomical features of the fingers and the speed of mastering movements. For track and field athletes of the population of Ukraine, there were characteristic features of the dermatoglyphic structure: higher values of the deltoid index and genetic markers of the distance between the triradii a and d of the fingers.

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium.

Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium-phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium-phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.

Influence of LYS198ASN polymorphism of endothelin-1 gene on ischemic atherothrombotic stroke characteristics.

OBJECTIVE: The aim: Investigate the effect of Lys198Asn polymorphism of the EDN1 gene on ischemic atherothrombotic stroke characteristics. PATIENTS AND METHODS: Materials and methods: Venous blood of 170 patients with ischemic atherothrombotic stroke (IAS) and 124 patients without cerebrovascular pathology, who made up the control group, used for the study. Lys198Asn (rs5370) polymorphism of the EDN1 gene was determined by the polymerase chain reaction method followed by restriction fragment length analysis. Statistical analysis was performed using SPSS-17.0. The values of Р < 0.05 were considered reliable. RESULTS: Results: An association between the Lys198Asn polymorphism of the EDN1 gene and the IAS development was detected. For Asn/Asn genotype carriers, the risk of IAS developing is 4 times higher than that of homozygotes for the major allele. The association of this polymorphism with the arterial pool, whose atherothrombotic changes lead to the development of IAS, was found in individuals with BMI < 25 kg/m2. Lys198Asn polymorphism also affects the severity of IAS in persons with hypertension and non-smokers. CONCLUSION: Conclusion: The Lys198Asn polymorphism of the EDN1 gene influences some characteristics of ischemic stroke.

[Role of c+70g single nucleotide polymorphism of endothelin receptor a gene in the development of ischemic atherothrombotic stroke].

INTRODUCTION: Endothelial dysfunction is the basic pathogenic development mechanism of ischemic atherothrombotic stroke (IAS). One of the reasons for changes of endothelin structure and properties and its receptor can be genetic polymorphism of their genes. AIM: Study of C+70G polymorphic variant associations of endothelin receptor A gene (EDNRA) with IAS development became the goal of research. MATERIAL AND METHODS: Venous blood of 170 patients with IAS and 124 persons without cerebrovascular pathology was used for the research. The groups did not differ in the ratio of two sexes (P = 0,294 for the ?2-test), but the average age of the first group (76,7 ± 0,93 years) was significantly higher than that of the second one (P < 0,001). Determination of allelic variant of EDNRA gene by C+70G polymorphism was carried out using method of polymerase chain reaction with further analysis of restriction fragment length. RESULTS: As a result of the conducted genotyping, it has been discovered that homozygote correlation by the main allele (CC), heterozygotes (CG) and homozygotes by minor allele (GG) does not differ authentically in patients with IAS and control group (24.1 %, 57.6 %, 8.2 % against 29.0 %, 50.0 %, 21.0 %; ? = 0.426). It is shown that association of the studied genetic marker with the scope of brain damage, localization of atherothrombotic process, course severity, recurrence and neurological manifestations of IAS. CONCLUSIONS: There is no association between the C+70G polymorphism of the EDNRA gene and the development of IAS and its clinical characteristics.