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Rev Esp Med Nucl ; 21(1): 17-23, 2002 Feb.
Article in Spanish | MEDLINE | ID: mdl-11820997

ABSTRACT

A pilot study was carried out in the Nuclear Medicine Department of the National Institute of Oncology and Radiobiology to learn the diagnostic efficacy of the 99mTc-HMPAO scintigraphy in the detection of cutaneous melanoma, distant and local metastases, in patients with a confirmed histological diagnosis. The planar and/or SPECT scintigraphy was performed in 17 patients and revealed 90% sensitivity for the detection of the disease. We calculated the tumor/background index in all the images obtained and found a value greater than 1 in every case. Thus, we can affirm that the 99mTc-HMPAO accumulation in tumors was higher than the background in all cases. We recommend that this procedure be considered in the follow up of these patients as a new diagnostic method which is very useful in the determination of the patient stage and prognostic evaluation.


Subject(s)
Melanoma/diagnostic imaging , Neoplasm Metastasis/diagnostic imaging , Neoplasm Recurrence, Local/diagnostic imaging , Radiopharmaceuticals , Skin Neoplasms/diagnostic imaging , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon , Adult , Aged , Aged, 80 and over , False Negative Reactions , False Positive Reactions , Female , Follow-Up Studies , Humans , Male , Melanoma/pathology , Melanoma/surgery , Middle Aged , Pilot Projects , Sensitivity and Specificity , Skin Neoplasms/pathology , Skin Neoplasms/surgery
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